Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:cholesterol esterification
go back to main search page
Accession:GO:0034435 term browser browse the term
Definition:A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.


show annotations for term's descendants           Sort by:
 
cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LCAT lecithin-cholesterol acyltransferase involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 6:28,550,356...28,553,561
Ensembl chr 6:28,550,357...28,553,567
JBrowse link
G SOAT1 sterol O-acyltransferase 1 involved_in IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 9:121,045,211...121,112,393
Ensembl chr 9:121,045,232...121,113,693
JBrowse link
G SOAT2 sterol O-acyltransferase 2 involved_in IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 5:18,358,941...18,371,262
Ensembl chr 5:18,358,673...18,371,264
JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 involved_in ISO (MGI:5295922|PMID:21767660) CACAO PMID:21767660 MGI:5295922 NCBI chr 2:116,235,821...116,257,143
Ensembl chr 2:116,235,816...116,257,041
JBrowse link
negative regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484)
PMID:24201375
ARUK-UCL PMID:21810484 PMID:24201375 RGD:14697729
positive regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,672,428
JBrowse link
G AGTR1 angiotensin II receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:88,934,873...88,980,317
Ensembl chr13:88,934,868...88,983,131
JBrowse link
G APOA1 apolipoprotein A1 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,393...44,218,978
JBrowse link
G APOA2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:89,237,514...89,239,126
Ensembl chr 4:89,237,511...89,240,320
JBrowse link
G APOA4 apolipoprotein A4 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 9:44,201,587...44,204,072
Ensembl chr 9:44,201,508...44,204,206
JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,259...51,377,794
JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:116,235,821...116,257,143
Ensembl chr 2:116,235,816...116,257,041
JBrowse link
regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:15238223)
(PMID:24201375)
UniProt
ARUK-UCL
PMID:15238223 PMID:24201375
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852) BHF-UCL PMID:16556852 MGI:3852307 NCBI chr13:205,561,897...205,628,428
Ensembl chr13:205,561,951...205,628,425
JBrowse link
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:6,674,045...6,680,067
Ensembl chr 9:6,672,475...6,680,053
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16573
    metabolic process 10410
      cellular metabolic process 9486
        cellular lipid metabolic process 920
          lipid modification 211
            steroid esterification 13
              sterol esterification 13
                cholesterol esterification 13
                  negative regulation of cholesterol esterification 1
                  positive regulation of cholesterol esterification 7
                  regulation of cholesterol esterification + 10
Path 2
Term Annotations click to browse term
  biological_process 16573
    metabolic process 10410
      primary metabolic process 9286
        lipid metabolic process 1221
          cellular lipid metabolic process 920
            lipid modification 211
              steroid esterification 13
                sterol esterification 13
                  cholesterol esterification 13
                    negative regulation of cholesterol esterification 1
                    positive regulation of cholesterol esterification 7
                    regulation of cholesterol esterification + 10
paths to the root