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ONTOLOGY REPORT - ANNOTATIONS


Term:cholesterol esterification
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Accession:GO:0034435 term browser browse the term
Definition:A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.


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cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lcat lecithin cholesterol acyltransferase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:105,939,551...105,943,402
Ensembl chr 8:105,939,551...105,943,382
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 involved_in IMP (MGI:1889921|PMID:10899171) UniProt PMID:10899171 MGI:1889921 NCBI chr19:44,394,450...44,407,709
Ensembl chr19:44,394,455...44,407,879
JBrowse link
G Soat1 sterol O-acyltransferase 1 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 1:156,428,108...156,474,328
Ensembl chr 1:156,424,525...156,474,331
JBrowse link
G Soat2 sterol O-acyltransferase 2 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr15:102,150,415...102,163,469
Ensembl chr15:102,150,526...102,163,469
JBrowse link
G Stard4 StAR-related lipid transfer (START) domain containing 4 involved_in IDA (MGI:5295922|PMID:21767660) CACAO PMID:21767660 MGI:5295922 NCBI chr18:33,199,138...33,213,862
Ensembl chr18:33,199,355...33,213,862
JBrowse link
negative regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP-binding cassette, sub-family A (ABC1), member 2 acts_upstream_of ISO MGI GO_REF:0000096 MGI:4417868 MGI:4834177 NCBI chr 2:25,428,599...25,448,544
Ensembl chr 2:25,428,703...25,448,540
JBrowse link
positive regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:124,556,587...124,569,706
Ensembl chr 8:124,556,534...124,569,706
JBrowse link
G Agtr1a angiotensin II receptor, type 1a involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:30,336,356...30,382,867
Ensembl chr13:30,336,441...30,382,867
JBrowse link
G Agtr1b angiotensin II receptor, type 1b involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:20,314,473...20,367,177
Ensembl chr 3:20,314,473...20,367,177
JBrowse link
G Apoa1 apolipoprotein A-I involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 9:46,228,630...46,230,469
Ensembl chr 9:46,228,580...46,230,466
JBrowse link
G Apoa2 apolipoprotein A-II involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:171,221,564...171,226,379
Ensembl chr 1:171,225,054...171,226,379
JBrowse link
G Apoa4 apolipoprotein A-IV involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 9:46,240,844...46,243,458
Ensembl chr 9:46,240,696...46,243,459
JBrowse link
G Apoa5 apolipoprotein A-V involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:46,268,608...46,271,921
Ensembl chr 9:46,268,633...46,271,919
JBrowse link
G Apoe apolipoprotein E involved_in IMP
ISO
(MGI:3850619|PMID:15654758) BHF-UCL
MGI
PMID:15654758 GO_REF:0000096 MGI:3850619 MGI:4834177 NCBI chr 7:19,696,244...19,701,310
Ensembl chr 7:19,696,109...19,699,188
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 involved_in TAS (MGI:1927704|PMID:11090130) BHF-UCL PMID:11090130 MGI:1927704 NCBI chr19:44,394,450...44,407,709
Ensembl chr19:44,394,455...44,407,879
JBrowse link
G Stard4 StAR-related lipid transfer (START) domain containing 4 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr18:33,199,138...33,213,862
Ensembl chr18:33,199,355...33,213,862
JBrowse link
regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP-binding cassette, sub-family A (ABC1), member 2 acts_upstream_of ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:25,428,599...25,448,544
Ensembl chr 2:25,428,703...25,448,540
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in IMP (MGI:3852307|PMID:16556852) BHF-UCL PMID:16556852 MGI:3852307 NCBI chr17:31,057,694...31,117,984
Ensembl chr17:31,057,675...31,117,988
JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:101,905,837...101,911,903
Ensembl chr 7:101,905,904...101,926,675
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28616
    metabolic process 11239
      cellular metabolic process 10124
        cellular lipid metabolic process 1028
          lipid modification 221
            steroid esterification 16
              sterol esterification 16
                cholesterol esterification 16
                  negative regulation of cholesterol esterification 1
                  positive regulation of cholesterol esterification 10
                  regulation of cholesterol esterification + 13
Path 2
Term Annotations click to browse term
  biological_process 28616
    metabolic process 11239
      primary metabolic process 9930
        lipid metabolic process 1384
          cellular lipid metabolic process 1028
            lipid modification 221
              steroid esterification 16
                sterol esterification 16
                  cholesterol esterification 16
                    negative regulation of cholesterol esterification 1
                    positive regulation of cholesterol esterification 10
                    regulation of cholesterol esterification + 13
paths to the root