Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer VCMap
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:cholesterol esterification
go back to main search page
Accession:GO:0034435 term browser browse the term
Definition:A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.


show annotations for term's descendants           Sort by:
 
cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lcat lecithin cholesterol acyltransferase involved_in ISS
ISO		 GO_REF:0000024
(PMID:24620755), (PMID:26195816), (PMID:3458198), (PMID:4335615)		 UniProt
RGD		 PMID:3458198 PMID:4335615 PMID:24620755 PMID:26195816 GO_REF:0000024 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231 		JBrowse link
G Scd stearoyl-CoA desaturase involved_in ISO (MGI:1889921|PMID:10899171) RGD PMID:10899171 MGI:1889921 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Soat1 sterol O-acyltransferase 1 involved_in ISO
IBA
ISS
IEA		 (PMID:16647063), (PMID:32433613), (PMID:32433614), (PMID:8407899)
(PMID:32433613), (PMID:32433614)
PMID:21873635
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:8407899 PMID:16647063 PMID:32433613 PMID:32433614 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr13:68,552,274...68,597,529
Ensembl chr13:68,552,317...68,597,494 		JBrowse link
G Soat2 sterol O-acyltransferase 2 involved_in ISS
ISO
IBA
IEA		 GO_REF:0000024
(PMID:11294643)
PMID:21873635
GO_REF:0000107
(PMID:11294643), (PMID:16647063)		 UniProt
RGD
Ensembl		 PMID:11294643 PMID:16647063 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 7:133,281,818...133,294,915
Ensembl chr 7:133,281,818...133,294,915 		JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 involved_in ISO (MGI:5295922|PMID:21767660) RGD PMID:21767660 MGI:5295922 NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024 		JBrowse link
negative regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484) RGD PMID:21810484 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
positive regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO (PMID:18971559) RGD PMID:18971559 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a involved_in ISO (PMID:18971559) RGD PMID:18971559 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Apoa1 apolipoprotein A1 involved_in IBA
ISO		 PMID:21873635
(PMID:4335615)		 RGD PMID:4335615 PMID:21873635 RGD:13792537 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:14967812) RGD PMID:14967812 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Apoa4 apolipoprotein A4 involved_in ISO
IBA		 (PMID:1935934)
PMID:21873635		 RGD PMID:1935934 PMID:21873635 RGD:13792537 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Apoa5 apolipoprotein A5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816 		JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:15654758)
(MGI:3850619|PMID:15654758)		 RGD PMID:15654758 MGI:3850619 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 involved_in ISO (PMID:18403318) RGD PMID:18403318 NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024 		JBrowse link
regulation of cholesterol esterification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15238223)
(PMID:15238223), (PMID:24201375)		 UniProt
Ensembl
RGD		 PMID:15238223 PMID:24201375 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852) RGD PMID:16556852 MGI:3852307 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948 		JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20544018)		 UniProt
RGD		 PMID:20544018 GO_REF:0000024 NCBI chr 1:156,272,116...156,277,687
Ensembl chr 1:156,272,064...156,291,179 		JBrowse link
G LOC100361543 RhoA activator C11orf59-like involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:34,637,461...34,638,516
Ensembl chr  X:34,637,459...34,638,516 		JBrowse link
G Mir27a microRNA 27a involved_in ISO (PMID:24608080) RGD PMID:24608080 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Mir27b microRNA 27b involved_in ISO (PMID:24608080) RGD PMID:24608080 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18872
    metabolic process 11588
      cellular metabolic process 9824
        cellular lipid metabolic process 1050
          lipid modification 233
            steroid esterification 18
              sterol esterification 18
                cholesterol esterification 18
                  negative regulation of cholesterol esterification 1
                  positive regulation of cholesterol esterification 8
                  regulation of cholesterol esterification + 14
Path 2
Term Annotations click to browse term
  biological_process 18872
    metabolic process 11588
      primary metabolic process 10391
        lipid metabolic process 1430
          cellular lipid metabolic process 1050
            lipid modification 233
              steroid esterification 18
                sterol esterification 18
                  cholesterol esterification 18
                    negative regulation of cholesterol esterification 1
                    positive regulation of cholesterol esterification 8
                    regulation of cholesterol esterification + 14
paths to the root