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ONTOLOGY REPORT - ANNOTATIONS


Term:steroid esterification
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Accession:GO:0034433 term browser browse the term
Definition:A lipid modification process in which a steroid ester is formed by the combination of a carboxylic acid (often a fatty acid) and a steroid molecule (e.g. cholesterol).


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cholesterol esterification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LCAT lecithin-cholesterol acyltransferase ISO (PMID:24620755), (PMID:26195816), (PMID:3458198), (PMID:4335615) UniProt PMID:3458198, PMID:4335615, PMID:24620755, PMID:26195816 NCBI chr16:48,278,137...48,285,305
Ensembl chr16:67,668,646...67,673,127
JBrowse link
G SOAT1 sterol O-acyltransferase 1 ISO (PMID:8407899)
(PMID:16647063), (PMID:32433613), (PMID:32433614)
BHF-UCL PMID:8407899, PMID:16647063, PMID:32433613, PMID:32433614 NCBI chr 1:154,776,305...154,840,594
Ensembl chr 1:158,464,886...158,524,909
JBrowse link
G SOAT2 sterol O-acyltransferase 2 ISO (PMID:11294643), (PMID:16647063) UniProt PMID:11294643, PMID:16647063 NCBI chr12:35,632,018...35,653,227
Ensembl chr12:36,413,954...36,434,074
JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 ISO (MGI:MGI:5295922|PMID:21767660) CACAO PMID:21767660 MGI:MGI:5295922 NCBI chr 5:106,855,990...106,873,384
Ensembl chr 5:112,657,516...112,675,165
JBrowse link
negative regulation of cholesterol esterification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 ISO PMID:24201375
(PMID:21810484)
ARUK-UCL PMID:21810484, PMID:24201375 RGD:14697729 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776
JBrowse link
positive regulation of cholesterol esterification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO (PMID:18971559) BHF-UCL PMID:18971559 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044
JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO (PMID:18971559) BHF-UCL PMID:18971559 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380
JBrowse link
G APOA1 apolipoprotein A1 ISO (PMID:4335615) BHF-UCL PMID:4335615 NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122
JBrowse link
G APOA2 apolipoprotein A2 ISO (PMID:14967812) BHF-UCL PMID:14967812 NCBI chr 1:136,634,754...136,636,122 JBrowse link
G APOA4 apolipoprotein A4 ISO (PMID:1935934) BHF-UCL PMID:1935934 NCBI chr11:111,659,186...111,661,790
Ensembl chr11:115,591,788...115,594,382
JBrowse link
G APOE apolipoprotein E ISO (PMID:15654758)
(MGI:MGI:3850619|PMID:15654758)
BHF-UCL PMID:15654758 MGI:MGI:3850619 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490
JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 ISO (PMID:18403318) BHF-UCL PMID:18403318 NCBI chr 5:106,855,990...106,873,384
Ensembl chr 5:112,657,516...112,675,165
JBrowse link
regulation of cholesterol esterification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 ISO (PMID:24201375) ARUK-UCL PMID:24201375 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776
JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 ISO (MGI:MGI:3852307|PMID:16556852) BHF-UCL PMID:16556852 MGI:MGI:3852307 NCBI chr21:28,534,697...28,619,590 JBrowse link
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 ISO (PMID:20544018) UniProtKB PMID:20544018 NCBI chr11:67,177,580...67,183,631
Ensembl chr11:70,390,141...70,407,246
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12529
    metabolic process 7962
      cellular metabolic process 7310
        cellular lipid metabolic process 761
          lipid modification 173
            steroid esterification 13
              sterol esterification + 13
Path 2
Term Annotations click to browse term
  biological_process 12529
    metabolic process 7962
      primary metabolic process 7030
        lipid metabolic process 985
          cellular lipid metabolic process 761
            lipid modification 173
              steroid esterification 13
                sterol esterification + 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.