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ONTOLOGY REPORT - ANNOTATIONS


Term:Pwp2p-containing subcomplex of 90S preribosome
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Accession:GO:0034388 term browser browse the term
Definition:A protein complex that forms a subcomplex of the 90S preribosome and can interact directly with the 5' External Transcribed Spacer (ETS) of the full length pre-rRNA transcript. In S. cerevisiae, it sediments at 25-30 S and is composed of Pwp2p, Dip2p, Utp21p, Utp13p, Utp18p, and Utp6p.
Comment:Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.
Synonyms:exact_synonym: 25-30 S subcomplex of 90S preribosome;   UTP-B complex


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Pwp2p-containing subcomplex of 90S preribosome term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pwp2 PWP2, small subunit processome component IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:11,228,892...11,243,204
Ensembl chr20:11,228,844...11,243,205
JBrowse link
G Utp18 UTP18 small subunit processome component IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:81,560,929...81,588,156
Ensembl chr10:81,562,409...81,587,858
JBrowse link
G Utp6 UTP6 small subunit processome component IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:67,255,177...67,285,754
Ensembl chr10:67,257,161...67,285,617
JBrowse link
G Wdr3 WD repeat domain 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:202,447,749...202,470,398
Ensembl chr 2:202,447,745...202,470,399
JBrowse link
G Wdr36 WD repeat domain 36 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:25,637,475...25,665,801
Ensembl chr18:25,637,588...25,665,639
JBrowse link

Term paths to the root
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  cellular_component 20609
    protein-containing complex 6093
      Pwp2p-containing subcomplex of 90S preribosome 5
Path 2
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  cellular_component 20609
    cellular anatomical entity 20358
      intracellular anatomical structure 14706
        intracellular organelle 12912
          intracellular membrane-bounded organelle 10704
            nucleus 7183
              nuclear lumen 4262
                nucleolus 938
                  Pwp2p-containing subcomplex of 90S preribosome 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.