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ONTOLOGY REPORT - ANNOTATIONS


Term:high-density lipoprotein particle clearance
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Accession:GO:0034384 term browser browse the term
Definition:The process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
Synonyms:exact_synonym: HDL clearance



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high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in IC (PMID:12651854) BHF-UCL PMID:12651854 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
JBrowse link
G APOA2 apolipoprotein A2 involved_in IDA (PMID:10764676) BHF-UCL PMID:10764676 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631
JBrowse link
G APOC2 apolipoprotein C2 involved_in IMP
IEA
(PMID:15778093) BHF-UCL
TreeGrafter
PMID:15778093 GO_REF:0000118 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,946,035...44,949,565
JBrowse link
G APOE apolipoprotein E involved_in IDA (PMID:210175) BHF-UCL PMID:210175 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G APOM apolipoprotein M involved_in IEA
IBA
ISS
(PMID:15793583) Ensembl
TreeGrafter
GO_Central
BHF-UCL
PMID:15793583 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:31,652,404...31,658,210
Ensembl chr 6:31,652,416...31,658,210
JBrowse link
G LDLR low density lipoprotein receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820
JBrowse link
G SCARB1 scavenger receptor class B member 1 involved_in IDA (PMID:23459944), (PMID:9211901) BHF-UCL PMID:9211901 PMID:23459944 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
JBrowse link
negative regulation of high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC3 apolipoprotein C3 involved_in IMP
IBA
IEA
(PMID:15778093) BHF-UCL
GO_Central
TreeGrafter
PMID:15778093 GO_REF:0000033 GO_REF:0000118 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072
JBrowse link
G MIR185 microRNA 185 involved_in IDA (PMID:23459944) BHF-UCL PMID:23459944 NCBI chr22:20,033,139...20,033,220
Ensembl chr22:20,033,139...20,033,220
JBrowse link
G MIR223 microRNA 223 involved_in IDA (PMID:23459944) BHF-UCL PMID:23459944 NCBI chr  X:66,018,870...66,018,979
Ensembl chr  X:66,018,870...66,018,979
JBrowse link
G MIR96 microRNA 96 involved_in IDA (PMID:23459944) BHF-UCL PMID:23459944 NCBI chr 7:129,774,692...129,774,769
Ensembl chr 7:129,774,692...129,774,769
JBrowse link
positive regulation of high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:24,423,969...24,495,287
Ensembl chr 6:24,424,565...24,495,205
JBrowse link
G LIPG lipase G, endothelial type involved_in IMP (PMID:19136670) BHF-UCL PMID:19136670 NCBI chr18:49,561,479...49,599,185
Ensembl chr18:49,560,699...49,599,185
JBrowse link
G MIR144 microRNA 144 involved_in ISS (PMID:23519695) BHF-UCL PMID:23519695 NCBI chr17:28,861,533...28,861,618
Ensembl chr17:28,861,533...28,861,618
JBrowse link
G MIR302A microRNA 302a involved_in ISS (PMID:25524771) BHF-UCL PMID:25524771 NCBI chr 4:112,648,183...112,648,251
Ensembl chr 4:112,648,183...112,648,251
JBrowse link
G MIR33A microRNA 33a involved_in ISS (PMID:20466885) BHF-UCL PMID:20466885 NCBI chr22:41,900,944...41,901,012
Ensembl chr22:41,900,944...41,901,012
JBrowse link
G MIR33B microRNA 33b involved_in IMP (PMID:24931346) BHF-UCL PMID:24931346 NCBI chr17:17,813,836...17,813,931
Ensembl chr17:17,813,836...17,813,931
JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA
ISS
Ensembl
ARUK-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    multicellular organismal process 8456
      plasma lipoprotein particle clearance 62
        high-density lipoprotein particle clearance 18
          negative regulation of high-density lipoprotein particle clearance 4
          positive regulation of high-density lipoprotein particle clearance 7
          regulation of high-density lipoprotein particle clearance + 11
Path 2
Term Annotations click to browse term
  biological_process 19669
    biological regulation 13397
      regulation of biological process 13016
        regulation of plasma lipoprotein particle levels 104
          plasma lipoprotein particle clearance 62
            high-density lipoprotein particle clearance 18
              negative regulation of high-density lipoprotein particle clearance 4
              positive regulation of high-density lipoprotein particle clearance 7
              regulation of high-density lipoprotein particle clearance + 11
paths to the root