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ONTOLOGY REPORT - ANNOTATIONS

Term:plasma lipoprotein particle clearance
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Accession:GO:0034381 term browser browse the term
Definition:The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
Synonyms:exact_synonym: lipoprotein particle clearance


show annotations for term's descendants           Sort by:
plasma lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule involved_in IMP (MGI:2447499|PMID:12376530) BHF-UCL PMID:12376530 MGI:2447499 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in IDA (MGI:5902678|PMID:22383525) ARUK-UCL PMID:22383525 MGI:5902678 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215 		JBrowse link
G Msr1 macrophage scavenger receptor 1 involved_in IMP
IBA		 (MGI:2447499|PMID:12376530) BHF-UCL
GO_Central		 PMID:12376530 GO_REF:0000033 MGI:2447499 NCBI chr 8:39,996,284...40,095,790
Ensembl chr 8:40,034,726...40,095,714 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158 		JBrowse link
chylomicron remnant clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C-I involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:19,423,405...19,426,584
Ensembl chr 7:19,423,406...19,426,585 		JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:19,405,504...19,411,866
Ensembl chr 7:19,405,504...19,411,866 		JBrowse link
G Apoc2l apolipoprotein C2 like involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:19,405,504...19,415,385
Ensembl chr 7:19,405,509...19,415,348 		JBrowse link
G Apoc3 apolipoprotein C-III involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934 		JBrowse link
G Apoe apolipoprotein E involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Lipc lipase, hepatic involved_in ISO RGD
MGI		 PMID:8192680 GO_REF:0000096 MGI:4417868 RGD:2308768 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508 		JBrowse link
G Lmf1 lipase maturation factor 1 acts_upstream_of_or_within IMP (PMID:6857276) MGI PMID:6857276 NCBI chr17:25,798,143...25,886,381
Ensembl chr17:25,798,059...25,881,800 		JBrowse link
high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A-II involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948 		JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:19,405,504...19,411,866
Ensembl chr 7:19,405,504...19,411,866 		JBrowse link
G Apoc2l apolipoprotein C2 like involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:19,405,504...19,415,385
Ensembl chr 7:19,405,509...19,415,348 		JBrowse link
G Apoe apolipoprotein E involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Apom apolipoprotein M involved_in IMP
IBA		 (MGI:3575626|PMID:15793583) BHF-UCL
GO_Central		 PMID:15793583 GO_REF:0000033 MGI:3575626 NCBI chr17:35,347,973...35,350,777
Ensembl chr17:35,347,973...35,351,026 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in IGI (MGI:5896906|PMID:25524771) BHF-UCL PMID:25524771 MGI:5896906 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in ISS
ISO		 (MGI:894255|PMID:9211901) BHF-UCL
MGI		 PMID:9211901 GO_REF:0000119 MGI:4834177 MGI:894255 NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158 		JBrowse link
intermediate-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Apob apolipoprotein B involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835 		JBrowse link
G Cd36 CD36 molecule involved_in IMP
IBA
ISO		 (MGI:3836139|PMID:10772654) BHF-UCL
GO_Central
MGI		 PMID:10772654 GO_REF:0000033 GO_REF:0000119 MGI:3836139 MGI:4834177 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G Commd1 COMM domain containing 1 acts_upstream_of_or_within IMP (PMID:26965651) MGI PMID:26965651 NCBI chr11:22,849,728...22,934,539
Ensembl chr11:22,846,136...22,932,382 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 involved_in IMP (MGI:3784112|PMID:18175806) BHF-UCL PMID:18175806 MGI:3784112 NCBI chr 7:98,802,870...98,831,920
Ensembl chr 7:98,802,865...98,831,926 		JBrowse link
G Ehd1 EH-domain containing 1 involved_in IMP (MGI:3711403|PMID:17451652) BHF-UCL PMID:17451652 MGI:3711403 NCBI chr19:6,326,926...6,350,126
Ensembl chr19:6,326,755...6,350,126 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in
acts_upstream_of_or_within		 IMP
IDA
ISO		 (MGI:3784112|PMID:18175806)
(PMID:26965651)		 BHF-UCL
MGI		 PMID:18175806 PMID:26965651 GO_REF:0000119 MGI:3784112 MGI:4834177 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:134,468,865...134,495,342
Ensembl chr 4:134,468,865...134,495,335 		JBrowse link
G Lipc lipase, hepatic involved_in ISO RGD
MGI		 PMID:8071607 GO_REF:0000096 MGI:4417868 RGD:2308769 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in IMP (MGI:3784112|PMID:18175806) BHF-UCL PMID:18175806 MGI:3784112 NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158 		JBrowse link
G Washc1 WASH complex subunit 1 acts_upstream_of_or_within IMP (PMID:26965651) MGI PMID:26965651 NCBI chr17:66,418,524...66,427,498
Ensembl chr17:66,418,540...66,427,498 		JBrowse link
negative regulation of high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc3 apolipoprotein C-III involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934 		JBrowse link
G Mir185 microRNA 185 involved_in ISO (PMID:23459944) BHF-UCL PMID:23459944 NCBI chr16:18,145,265...18,145,329
Ensembl chr16:18,145,265...18,145,329 		JBrowse link
G Mir223 microRNA 223 involved_in ISO (PMID:23459944) BHF-UCL PMID:23459944 NCBI chr  X:95,286,423...95,286,532
Ensembl chr  X:95,286,423...95,286,532 		JBrowse link
G Mir96 microRNA 96 involved_in ISO (PMID:23459944) BHF-UCL PMID:23459944 NCBI chr 6:30,169,445...30,169,550
Ensembl chr 6:30,169,445...30,169,550 		JBrowse link
negative regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP-binding cassette, sub-family C member 8 involved_in ISO RGD
MGI		 PMID:23828271 GO_REF:0000096 MGI:4417868 RGD:12792253 NCBI chr 7:45,753,952...45,829,441
Ensembl chr 7:45,753,947...45,829,457 		JBrowse link
G Apoc3 apolipoprotein C-III involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934 		JBrowse link
G Csk c-src tyrosine kinase involved_in ISO RGD
MGI		 PMID:10884975 GO_REF:0000096 MGI:4417868 RGD:5134370 NCBI chr 9:57,533,929...57,560,758
Ensembl chr 9:57,533,929...57,560,914 		JBrowse link
G Il19 interleukin 19 involved_in IMP (MGI:6102526|PMID:28257760) BHF-UCL PMID:28257760 MGI:6102526 NCBI chr 1:130,860,393...130,873,194
Ensembl chr 1:130,860,393...130,867,852 		JBrowse link
G Khsrp KH-type splicing regulatory protein involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:57,328,049...57,338,507
Ensembl chr17:57,328,051...57,338,522 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215 		JBrowse link
G Mir133a-1 microRNA 133a-1 involved_in ISO (PMID:28257760) BHF-UCL PMID:28257760 NCBI chr18:10,782,909...10,782,976
Ensembl chr18:10,782,909...10,782,976 		JBrowse link
G Mir133a-2 microRNA 133a-2 involved_in ISO (PMID:28257760) BHF-UCL PMID:28257760 NCBI chr 2:180,040,172...180,040,275
Ensembl chr 2:180,040,172...180,040,275 		JBrowse link
G Mir148a microRNA 148a involved_in ISO (PMID:26437365) BHF-UCL PMID:26437365 NCBI chr 6:51,246,792...51,246,890
Ensembl chr 6:51,246,792...51,246,890 		JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:23285084) ARUK-UCL PMID:23285084 NCBI chr14:115,281,103...115,281,186
Ensembl chr14:115,281,103...115,281,186 		JBrowse link
G Mir185 microRNA 185 acts_upstream_of
involved_in		 ISO (PMID:24296663)
(PMID:26523989)		 BHF-UCL PMID:24296663 PMID:26523989 NCBI chr16:18,145,265...18,145,329
Ensembl chr16:18,145,265...18,145,329 		JBrowse link
G Mir199a-1 microRNA 199a-1 involved_in ISO (PMID:26163491) BHF-UCL PMID:26163491 NCBI chr 9:21,407,791...21,407,860
Ensembl chr 9:21,407,791...21,407,860 		JBrowse link
G Mir199a-2 microRNA 199a-2 involved_in ISO (PMID:26163491) BHF-UCL PMID:26163491 NCBI chr 1:162,045,383...162,045,492
Ensembl chr 1:162,045,383...162,045,492 		JBrowse link
G Mir27a microRNA 27a involved_in ISO (PMID:26318398) BHF-UCL PMID:26318398 NCBI chr 8:84,935,301...84,935,387
Ensembl chr 8:84,935,301...84,935,387 		JBrowse link
G Mir27b microRNA 27b involved_in ISO (PMID:26520906) BHF-UCL PMID:26520906 NCBI chr13:63,448,526...63,448,598
Ensembl chr13:63,448,526...63,448,598 		JBrowse link
G Mylip myosin regulatory light chain interacting protein involved_in IDA (MGI:3849777|PMID:19520913) BHF-UCL PMID:19520913 MGI:3849777 NCBI chr13:45,543,197...45,565,498
Ensembl chr13:45,543,218...45,565,498 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:106,299,531...106,321,522
Ensembl chr 4:106,299,526...106,321,526 		JBrowse link
negative regulation of very-low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C-I involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 7:19,423,405...19,426,584
Ensembl chr 7:19,423,406...19,426,585 		JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:19,405,504...19,411,866
Ensembl chr 7:19,405,504...19,411,866 		JBrowse link
G Apoc2l apolipoprotein C2 like involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:19,405,504...19,415,385
Ensembl chr 7:19,405,509...19,415,348 		JBrowse link
G Apoc3 apolipoprotein C-III involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934 		JBrowse link
G Lrpap1 low density lipoprotein receptor-related protein associated protein 1 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 5:35,248,834...35,263,043
Ensembl chr 5:35,248,845...35,263,110 		JBrowse link
oxidised low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
positive regulation of chylomicron remnant clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpihbp1 GPI-anchored HDL-binding protein 1 involved_in IMP (MGI:3770110|PMID:17403372) BHF-UCL PMID:17403372 MGI:3770110 NCBI chr15:75,468,479...75,470,062
Ensembl chr15:75,468,477...75,471,330 		JBrowse link
positive regulation of high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IMP (MGI:3617276|PMID:16219662) UniProt PMID:16219662 MGI:3617276 NCBI chr13:25,127,135...25,175,919
Ensembl chr13:25,127,135...25,176,484 		JBrowse link
G Lipg lipase, endothelial involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr18:75,072,393...75,095,380
Ensembl chr18:75,072,393...75,094,334 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in IMP (MGI:6342648|PMID:31257031) ARUK-UCL PMID:31257031 MGI:6342648 NCBI chr17:48,653,429...48,659,304
Ensembl chr17:48,653,429...48,661,175 		JBrowse link
positive regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in IMP (MGI:5446858|PMID:22848640) BHF-UCL PMID:22848640 MGI:5446858 NCBI chr 9:69,360,978...69,399,074
Ensembl chr 9:69,360,902...69,399,077 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:134,468,865...134,495,342
Ensembl chr 4:134,468,865...134,495,335 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in IMP (MGI:6342648|PMID:31257031) ARUK-UCL PMID:31257031 MGI:6342648 NCBI chr17:48,653,429...48,659,304
Ensembl chr17:48,653,429...48,661,175 		JBrowse link
regulation of chylomicron remnant clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1g carboxylesterase 1G acts_upstream_of_or_within IMP (PMID:23145182) MGI PMID:23145182 NCBI chr 8:94,028,997...94,063,837
Ensembl chr 8:94,028,997...94,063,936 		JBrowse link
regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnpy2 canopy FGF signaling regulator 2 acts_upstream_of IMP (MGI:5427047|PMID:22378787) BHF-UCL PMID:22378787 MGI:5427047 NCBI chr10:128,157,972...128,163,056
Ensembl chr10:128,158,328...128,163,422 		JBrowse link
G Crp C-reactive protein, pentraxin-related involved_in ISO RGD
MGI		 PMID:8305421 GO_REF:0000096 MGI:4417868 RGD:9586002 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K acts_upstream_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:58,538,946...58,551,157
Ensembl chr13:58,538,956...58,551,157 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447 		JBrowse link
triglyceride-rich lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IMP
ISO		 (MGI:5514108|PMID:23676495) UniProt
MGI		 PMID:23676495 GO_REF:0000119 MGI:4834177 MGI:5514108 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Lipa lysosomal acid lipase A acts_upstream_of_or_within IMP (PMID:33357458) MGI PMID:33357458 NCBI chr19:34,469,716...34,504,874
Ensembl chr19:34,469,718...34,504,874 		JBrowse link
very-low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C-I involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 7:19,423,405...19,426,584
Ensembl chr 7:19,423,406...19,426,585 		JBrowse link
G Apoe apolipoprotein E involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Vldlr very low density lipoprotein receptor involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr19:27,190,070...27,231,631
Ensembl chr19:27,193,884...27,231,631 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    multicellular organismal process 8901
      plasma lipoprotein particle clearance 50
        high-density lipoprotein particle clearance + 14
        low-density lipoprotein particle clearance + 33
        negative regulation of lipoprotein particle clearance + 23
        oxidised low-density lipoprotein particle clearance 1
        positive regulation of lipoprotein particle clearance + 6
        regulation of lipoprotein particle clearance + 34
        triglyceride-rich lipoprotein particle clearance + 10
        very-low-density lipoprotein particle clearance + 7
Path 2
Term Annotations click to browse term
  biological_process 28573
    biological regulation 13112
      regulation of biological process 12722
        regulation of plasma lipoprotein particle levels 83
          plasma lipoprotein particle clearance 50
            high-density lipoprotein particle clearance + 14
            low-density lipoprotein particle clearance + 33
            negative regulation of lipoprotein particle clearance + 23
            oxidised low-density lipoprotein particle clearance 1
            positive regulation of lipoprotein particle clearance + 6
            regulation of lipoprotein particle clearance + 34
            triglyceride-rich lipoprotein particle clearance + 10
            very-low-density lipoprotein particle clearance + 7
paths to the root