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ONTOLOGY REPORT - ANNOTATIONS


Term:plasma lipoprotein particle clearance
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Accession:GO:0034381 term browser browse the term
Definition:The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
Synonyms:exact_synonym: lipoprotein particle clearance


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plasma lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule (CD36 blood group) involved_in ISO (MGI:2447499|PMID:12376530) BHF-UCL PMID:12376530 MGI:2447499 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313
JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO (MGI:5902678|PMID:22383525) ARUK-UCL PMID:22383525 MGI:5902678 NCBI chrNW_004955495:2,114,702...2,135,584
Ensembl chrNW_004955495:2,114,434...2,138,056
JBrowse link
G Msr1 macrophage scavenger receptor 1 involved_in ISO (MGI:2447499|PMID:12376530) BHF-UCL PMID:12376530 MGI:2447499 NCBI chrNW_004955463:1,197,086...1,263,943
Ensembl chrNW_004955463:1,197,022...1,264,765
JBrowse link
chylomicron remnant clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:4020294) BHF-UCL PMID:4020294 NCBI chrNW_004955555:2,005,962...2,007,239 JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO (PMID:4020294) BHF-UCL PMID:4020294 NCBI chrNW_004955555:2,019,547...2,021,543
Ensembl chrNW_004955555:2,016,217...2,021,830
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:4020294) BHF-UCL PMID:4020294 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015
JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:7175379)
(PMID:1911868), (PMID:7683668)
BHF-UCL
UniProt
PMID:1911868 PMID:7175379 PMID:7683668 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888
JBrowse link
G Lipc lipase C, hepatic type ISO RGD PMID:8192680 RGD:2308768 NCBI chrNW_004955450:15,947,869...16,062,449
Ensembl chrNW_004955450:15,948,187...16,048,766
JBrowse link
G Lmf1 lipase maturation factor 1 acts_upstream_of_or_within ISO (PMID:6857276) MGI PMID:6857276 NCBI chrNW_004955442:16,250,131...16,360,907
Ensembl chrNW_004955442:16,245,081...16,360,846
JBrowse link
high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:10764676) BHF-UCL PMID:10764676 NCBI chrNW_004955468:12,977,956...12,979,282
Ensembl chrNW_004955468:12,977,956...12,979,753
JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO (PMID:15778093) BHF-UCL PMID:15778093 NCBI chrNW_004955555:2,019,547...2,021,543
Ensembl chrNW_004955555:2,016,217...2,021,830
JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:210175) BHF-UCL PMID:210175 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888
JBrowse link
G Apom apolipoprotein M involved_in ISO (MGI:3575626|PMID:15793583) BHF-UCL PMID:15793583 MGI:3575626 NCBI chrNW_004955437:190,609...192,781
Ensembl chrNW_004955437:190,609...197,342
JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO (MGI:5896906|PMID:25524771) BHF-UCL PMID:25524771 MGI:5896906 NCBI chrNW_004955495:2,114,702...2,135,584
Ensembl chrNW_004955495:2,114,434...2,138,056
JBrowse link
G Scarb1 scavenger receptor class B member 1 involved_in ISO (PMID:23459944), (PMID:9211901) BHF-UCL PMID:9211901 PMID:23459944 NCBI chrNW_004955482:4,813,502...4,836,479
Ensembl chrNW_004955482:4,813,955...4,837,392
JBrowse link
intermediate-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:1917954) UniProt PMID:1917954 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888
JBrowse link
low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO (PMID:11222466) BHF-UCL PMID:11222466 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402
JBrowse link
G Apob apolipoprotein B involved_in ISO (PMID:15797858), (PMID:2563166) BHF-UCL PMID:2563166 PMID:15797858 NCBI chrNW_004955469:3,437,422...3,478,408
Ensembl chrNW_004955469:3,436,450...3,478,424
JBrowse link
G Cd36 CD36 molecule (CD36 blood group) involved_in ISO (PMID:10772654)
(MGI:3836139|PMID:10772654)
BHF-UCL PMID:10772654 MGI:3836139 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313
JBrowse link
G Commd1 copper metabolism domain containing 1 acts_upstream_of_or_within ISO (PMID:26965651) MGI PMID:26965651 NCBI chrNW_004955424:21,962,837...22,067,745
Ensembl chrNW_004955424:21,927,079...22,050,371
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 involved_in ISO (MGI:3784112|PMID:18175806) BHF-UCL PMID:18175806 MGI:3784112 NCBI chrNW_004955414:16,059,781...16,089,727
Ensembl chrNW_004955414:16,059,781...16,089,727
JBrowse link
G Ehd1 EH domain containing 1 involved_in ISO (MGI:3711403|PMID:17451652) BHF-UCL PMID:17451652 MGI:3711403 NCBI chrNW_004955422:20,302,409...20,324,591
Ensembl chrNW_004955422:20,302,655...20,324,591
JBrowse link
G Ldlr low density lipoprotein receptor involved_in
acts_upstream_of_or_within
ISO (PMID:17142622), (PMID:6299582)
(PMID:26965651)
(MGI:3784112|PMID:18175806)
BHF-UCL
MGI
PMID:6299582 PMID:17142622 PMID:18175806 PMID:26965651 MGI:3784112 NCBI chrNW_004955495:2,114,702...2,135,584
Ensembl chrNW_004955495:2,114,434...2,138,056
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) BHF-UCL PMID:12417523 PMID:12464675 PMID:15166224 NCBI chrNW_004955452:5,081,919...5,102,349
Ensembl chrNW_004955452:5,081,556...5,095,182
JBrowse link
G Lipc lipase C, hepatic type ISO RGD PMID:8071607 RGD:2308769 NCBI chrNW_004955450:15,947,869...16,062,449
Ensembl chrNW_004955450:15,948,187...16,048,766
JBrowse link
G Scarb1 scavenger receptor class B member 1 involved_in ISO (MGI:3784112|PMID:18175806) BHF-UCL PMID:18175806 MGI:3784112 NCBI chrNW_004955482:4,813,502...4,836,479
Ensembl chrNW_004955482:4,813,955...4,837,392
JBrowse link
negative regulation of high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:15778093) BHF-UCL PMID:15778093 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015
JBrowse link
negative regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 ISO RGD PMID:23828271 RGD:12792253 NCBI chrNW_004955414:32,216,243...32,289,028
Ensembl chrNW_004955414:32,216,196...32,289,053
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:15778093) BHF-UCL PMID:15778093 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015
JBrowse link
G Csk C-terminal Src kinase ISO RGD PMID:10884975 RGD:5134370 NCBI chrNW_004955450:3,127,561...3,144,550
Ensembl chrNW_004955450:3,127,561...3,144,550
JBrowse link
G Il19 interleukin 19 involved_in ISO (MGI:6102526|PMID:28257760) BHF-UCL PMID:28257760 MGI:6102526 NCBI chrNW_004955406:42,376,102...42,384,902
Ensembl chrNW_004955406:42,376,104...42,384,902
JBrowse link
G Khsrp KH-type splicing regulatory protein involved_in ISO (PMID:26523989) BHF-UCL PMID:26523989 NCBI chrNW_004955495:3,183,083...3,194,356
Ensembl chrNW_004955495:3,183,179...3,193,376
JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO (PMID:17452316) ComplexPortal PMID:17452316 NCBI chrNW_004955495:2,114,702...2,135,584
Ensembl chrNW_004955495:2,114,434...2,138,056
JBrowse link
G Mylip myosin regulatory light chain interacting protein involved_in ISO (MGI:3849777|PMID:19520913) BHF-UCL PMID:19520913 MGI:3849777 NCBI chrNW_004955483:9,725,343...9,745,041
Ensembl chrNW_004955483:9,723,023...9,745,062
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:17328821), (PMID:22848640) BHF-UCL PMID:17328821 PMID:22848640 NCBI chrNW_004955464:4,424,583...4,439,805
Ensembl chrNW_004955464:4,425,435...4,439,842
JBrowse link
negative regulation of very-low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:1917954) BHF-UCL PMID:1917954 NCBI chrNW_004955555:2,005,962...2,007,239 JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO (PMID:1917954) BHF-UCL PMID:1917954 NCBI chrNW_004955555:2,019,547...2,021,543
Ensembl chrNW_004955555:2,016,217...2,021,830
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:1917954) BHF-UCL PMID:1917954 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015
JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 involved_in ISO (PMID:8083232) BHF-UCL PMID:8083232 NCBI chrNW_004955514:2,195,228...2,208,258
Ensembl chrNW_004955514:2,195,228...2,208,688
JBrowse link
oxidised low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule (CD36 blood group) involved_in ISO (PMID:27607416) ARUK-UCL PMID:27607416 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313
JBrowse link
positive regulation of chylomicron remnant clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpihbp1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 involved_in ISO (MGI:3770110|PMID:17403372) BHF-UCL PMID:17403372 MGI:3770110 NCBI chrNW_004955454:1,965,627...1,972,479
Ensembl chrNW_004955454:1,970,626...1,973,743
JBrowse link
positive regulation of high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (MGI:3617276|PMID:16219662) UniProt PMID:16219662 MGI:3617276 NCBI chrNW_004955483:2,501,751...2,552,855
Ensembl chrNW_004955483:2,502,345...2,552,689
JBrowse link
G Lipg lipase G, endothelial type involved_in ISO (PMID:19136670) BHF-UCL PMID:19136670 NCBI chrNW_004955402:34,666,757...34,689,726
Ensembl chrNW_004955402:34,667,036...34,687,568
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6342648|PMID:31257031) ARUK-UCL PMID:31257031 MGI:6342648 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697
JBrowse link
positive regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in ISO (PMID:22848640)
(MGI:5446858|PMID:22848640)
BHF-UCL PMID:22848640 MGI:5446858 NCBI chrNW_004955450:14,545,586...14,574,161
Ensembl chrNW_004955450:14,512,381...14,574,696
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO (PMID:28257760) BHF-UCL PMID:28257760 NCBI chrNW_004955452:5,081,919...5,102,349
Ensembl chrNW_004955452:5,081,556...5,095,182
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6342648|PMID:31257031) ARUK-UCL PMID:31257031 MGI:6342648 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697
JBrowse link
regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnpy2 canopy FGF signaling regulator 2 acts_upstream_of ISO (MGI:5427047|PMID:22378787) BHF-UCL PMID:22378787 MGI:5427047 NCBI chrNW_004955458:3,921,208...3,924,785
Ensembl chrNW_004955458:3,920,743...3,924,781
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K acts_upstream_of ISO (PMID:20371611) BHF-UCL PMID:20371611 NCBI chrNW_004955432:3,246,090...3,257,774
Ensembl chrNW_004955432:3,246,092...3,257,774
JBrowse link
G Nr1h4 nuclear receptor subfamily 1 group H member 4 involved_in ISO (PMID:12660231) UniProt PMID:12660231 NCBI chrNW_004955405:36,160,360...36,236,258
Ensembl chrNW_004955405:36,160,049...36,237,751
JBrowse link
triglyceride-rich lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:23676495)
(MGI:5514108|PMID:23676495)
UniProt PMID:23676495 MGI:5514108 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888
JBrowse link
G Lipa lipase A, lysosomal acid type acts_upstream_of_or_within ISO (PMID:33357458) MGI PMID:33357458 NCBI chrNW_004955425:3,718,291...3,755,942
Ensembl chrNW_004955425:3,718,206...3,756,142
JBrowse link
very-low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:15576844) BHF-UCL PMID:15576844 NCBI chrNW_004955555:2,005,962...2,007,239 JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:9649566)
(PMID:1917954), (PMID:2762297), (PMID:7683668)
BHF-UCL PMID:1917954 PMID:2762297 PMID:7683668 PMID:9649566 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888
JBrowse link
G Vldlr very low density lipoprotein receptor involved_in ISO (PMID:8083232) BHF-UCL PMID:8083232 NCBI chrNW_004955434:7,013,092...7,050,103
Ensembl chrNW_004955434:7,013,092...7,050,103
JBrowse link

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