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ONTOLOGY REPORT - ANNOTATIONS


Term:high-density lipoprotein particle remodeling
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Accession:GO:0034375 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.
Synonyms:exact_synonym: HDL remodeling



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high-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca5 ATP binding cassette subfamily A member 5 involved_in ISO (MGI:4454250|PMID:20382126) RGD PMID:20382126 MGI:4454250 NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852), (MGI:5634884|PMID:21481393) RGD PMID:16556852 PMID:21481393 MGI:3852307 MGI:5634884 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO
IEA
(PMID:21481393)
(PMID:21481393), (PMID:4335615)
GO_REF:0000107
RGD
Ensembl
PMID:4335615 PMID:21481393 GO_REF:0000107 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa2 apolipoprotein A2 involved_in IBA
ISO
PMID:21873635
(PMID:14967812), (PMID:8106353)
RGD PMID:8106353 PMID:14967812 PMID:21873635 RGD:13792537 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa4 apolipoprotein A4 involved_in ISO
IEA
(PMID:1935934)
GO_REF:0000107
RGD
Ensembl
PMID:1935934 GO_REF:0000107 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:17438339) RGD PMID:17438339 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA
UniProtKB:P08226 (PMID:12401887)
GO_REF:0000107
RGD
Ensembl
PMID:12401887 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apom apolipoprotein M involved_in IBA
ISO
PMID:21873635
(PMID:18006500)
(MGI:3575626|PMID:15793583)
RGD PMID:15793583 PMID:18006500 PMID:21873635 MGI:3575626, RGD:13792537 NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550
JBrowse link
G Lcat lecithin cholesterol acyltransferase involved_in ISO (PMID:10722751), (PMID:12167653), (PMID:15210842), (PMID:4335615) RGD PMID:4335615 PMID:10722751 PMID:12167653 PMID:15210842 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lipc lipase C, hepatic type involved_in IDA
ISO
IEA
(PMID:3244012)
GO_REF:0000107
RGD
Ensembl
PMID:3244012 PMID:8157689 GO_REF:0000107, RGD:2308770 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lipg lipase G, endothelial type involved_in ISO (PMID:19136670) RGD PMID:19136670 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
JBrowse link
G Pla2g3 phospholipase A2, group III involved_in ISO (PMID:18801741) RGD PMID:18801741 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913
JBrowse link
G Pltp phospholipid transfer protein involved_in ISO
IBA
(PMID:24369175), (PMID:29883800), (PMID:9132017)
PMID:21873635
RGD PMID:9132017 PMID:24369175 PMID:29883800 PMID:21873635 RGD:13792537 NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647
JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in ISO (MGI:3056693|PMID:15210842), (MGI:5634884|PMID:21481393) RGD PMID:15210842 PMID:21481393 MGI:3056693 MGI:5634884 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20099
    multicellular organismal process 8936
      plasma lipoprotein particle organization 41
        plasma lipoprotein particle remodeling 27
          high-density lipoprotein particle remodeling 14
            conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle 0
Path 2
Term Annotations click to browse term
  biological_process 20099
    cellular process 18695
      cellular component organization or biogenesis 6763
        cellular component organization 6510
          protein-containing complex organization 1827
            protein-containing complex remodeling 29
              protein-lipid complex remodeling 27
                plasma lipoprotein particle remodeling 27
                  high-density lipoprotein particle remodeling 14
                    conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle 0
paths to the root