ONTOLOGY REPORT - ANNOTATIONS
Term: low-density lipoprotein particle remodeling
Accession: GO:0034374
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Definition: The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.
Synonyms: exact_synonym: LDL remodeling; LDL remodelling; low-density lipoprotein particle remodelling
related_synonym: small dense LDL formation; small dense low-density lipoprotein particle formation
G
ABCG1
ATP binding cassette subfamily G member 1
involved_in
ISO
(PMID:16556852)
BHF-UCL
PMID:16556852
NCBI chr13:205,561,897...205,628,428
Ensembl chr13:205,561,951...205,628,425
G
APOA2
apolipoprotein A2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 4:89,237,514...89,239,126
Ensembl chr 4:89,237,511...89,240,319
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APOB
apolipoprotein B
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 3:117,250,096...117,316,200
Ensembl chr 3:117,250,096...117,316,200
G
APOE
apolipoprotein E
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330
G
LIPC
lipase C, hepatic type
involved_in
ISO IEA
RGD Ensembl
PMID:8071607
GO_REF:0000107 RGD:2308769
NCBI chr 1:113,433,684...113,604,139
Ensembl chr 1:113,433,687...113,583,963
G
LOC110259864
group 10 secretory phospholipase A2-like
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 3:7,623,326...7,641,061
Ensembl chr 3:7,623,312...7,642,002
G
MPO
myeloperoxidase
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr12:34,557,031...34,570,091
Ensembl chr12:34,556,408...34,567,904
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MTTP
microsomal triglyceride transfer protein
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:27471003)
Ensembl MGI
PMID:27471003
GO_REF:0000107
NCBI chr 8:120,820,660...120,871,468
Ensembl chr 8:120,820,656...120,879,388
G
PLA2G12B
phospholipase A2 group XIIB
acts_upstream_of_or_within
ISO
(PMID:27471003)
MGI
PMID:27471003
NCBI chr14:75,754,525...75,778,933
Ensembl chr14:75,753,727...75,778,800
G
PLA2G2E
phospholipase A2 group IIE
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:24910243)
Ensembl MGI
PMID:24910243
GO_REF:0000107
NCBI chr 6:78,278,080...78,282,253
Ensembl chr 6:78,278,284...78,282,377
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PLA2G3
phospholipase A2 group III
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr14:47,923,005...47,928,762
Ensembl chr14:47,923,954...47,928,810
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PLA2G5
phospholipase A2 group V
acts_upstream_of_or_within involved_in
ISO
(PMID:24910243) (PMID:14962950)
MGI UniProt
PMID:14962950 PMID:24910243
NCBI chr 6:78,365,697...78,376,383
Ensembl chr 6:78,302,062...78,376,220
G
PLA2G7
phospholipase A2 group VII
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 7:41,488,152...41,531,383
Ensembl chr 7:41,486,598...41,531,345
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