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ONTOLOGY REPORT - ANNOTATIONS


Term:low-density lipoprotein particle remodeling
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Accession:GO:0034374 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.
Synonyms:exact_synonym: LDL remodeling;   LDL remodelling;   low-density lipoprotein particle remodelling
 related_synonym: small dense LDL formation;   small dense low-density lipoprotein particle formation



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low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:16556852) BHF-UCL PMID:16556852 NCBI chr13:205,561,897...205,628,428
Ensembl chr13:205,561,951...205,628,425
JBrowse link
G APOA2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:89,237,514...89,239,126
Ensembl chr 4:89,237,511...89,240,319
JBrowse link
G APOB apolipoprotein B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:117,250,096...117,316,200
Ensembl chr 3:117,250,096...117,316,200
JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330
JBrowse link
G LIPC lipase C, hepatic type involved_in ISO
IEA
RGD
Ensembl
PMID:8071607 GO_REF:0000107 RGD:2308769 NCBI chr 1:113,433,684...113,604,139
Ensembl chr 1:113,433,687...113,583,963
JBrowse link
G LOC110259864 group 10 secretory phospholipase A2-like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:7,623,326...7,641,061
Ensembl chr 3:7,623,312...7,642,002
JBrowse link
G MPO myeloperoxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:34,557,031...34,570,091
Ensembl chr12:34,556,408...34,567,904
JBrowse link
G MTTP microsomal triglyceride transfer protein involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:27471003) Ensembl
MGI
PMID:27471003 GO_REF:0000107 NCBI chr 8:120,820,660...120,871,468
Ensembl chr 8:120,820,656...120,879,388
JBrowse link
G PLA2G12B phospholipase A2 group XIIB acts_upstream_of_or_within ISO (PMID:27471003) MGI PMID:27471003 NCBI chr14:75,754,525...75,778,933
Ensembl chr14:75,753,727...75,778,800
JBrowse link
G PLA2G2E phospholipase A2 group IIE involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24910243) Ensembl
MGI
PMID:24910243 GO_REF:0000107 NCBI chr 6:78,278,080...78,282,253
Ensembl chr 6:78,278,284...78,282,377
JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:47,923,005...47,928,762
Ensembl chr14:47,923,954...47,928,810
JBrowse link
G PLA2G5 phospholipase A2 group V acts_upstream_of_or_within
involved_in
ISO (PMID:24910243)
(PMID:14962950)
MGI
UniProt
PMID:14962950 PMID:24910243 NCBI chr 6:78,365,697...78,376,383
Ensembl chr 6:78,302,062...78,376,220
JBrowse link
G PLA2G7 phospholipase A2 group VII involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:41,488,152...41,531,383
Ensembl chr 7:41,486,598...41,531,345
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17652
    multicellular organismal process 8647
      plasma lipoprotein particle organization 41
        plasma lipoprotein particle remodeling 26
          low-density lipoprotein particle remodeling 13
Path 2
Term Annotations click to browse term
  biological_process 17652
    cellular process 17185
      cellular component organization or biogenesis 6709
        cellular component organization 6513
          protein-containing complex organization 1693
            protein-containing complex remodeling 28
              protein-lipid complex remodeling 26
                plasma lipoprotein particle remodeling 26
                  low-density lipoprotein particle remodeling 13
paths to the root