ONTOLOGY REPORT - ANNOTATIONS
Term: low-density lipoprotein particle remodeling
Accession: GO:0034374
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Definition: The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.
Synonyms: exact_synonym: LDL remodeling; LDL remodelling; low-density lipoprotein particle remodelling
related_synonym: small dense LDL formation; small dense low-density lipoprotein particle formation
G
ABCG1
ATP binding cassette subfamily G member 1
involved_in
IEA ISS
(PMID:16556852)
Ensembl BHF-UCL
PMID:16556852
GO_REF:0000107
NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,304,389
G
AGT
angiotensinogen
involved_in
NAS
(PMID:17069818)
BHF-UCL
PMID:17069818
NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
G
AGTR1
angiotensin II receptor type 1
involved_in
NAS
(PMID:17069818)
BHF-UCL
PMID:17069818
NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
G
APOA2
apolipoprotein A2
involved_in
IDA
(PMID:8106353)
BHF-UCL
PMID:8106353
NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,290...161,223,631
G
APOB
apolipoprotein B
involved_in
IMP
(PMID:15797858)
BHF-UCL
PMID:15797858
NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
G
APOE
apolipoprotein E
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
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CETP
cholesteryl ester transfer protein
involved_in
IDA IBA
(PMID:2833496)
BHF-UCL GO_Central
PMID:2833496
GO_REF:0000033
NCBI chr16:56,961,950...56,983,845
Ensembl chr16:56,961,923...56,983,845
G
LIPC
lipase C, hepatic type
involved_in
ISO IMP
(PMID:3244012)
RGD BHF-UCL
PMID:3244012 PMID:8071607
RGD:2308769
NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844
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MPO
myeloperoxidase
involved_in
IDA
(PMID:10772654)
BHF-UCL
PMID:10772654
NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
G
MTTP
microsomal triglyceride transfer protein
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:27471003)
Ensembl MGI
PMID:27471003
GO_REF:0000107
NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997
G
PLA2G10
phospholipase A2 group X
involved_in
IDA
(PMID:12021277)
UniProt
PMID:12021277
NCBI chr16:14,672,548...14,701,850
Ensembl chr16:14,672,548...14,694,308
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PLA2G10BP
phospholipase A2 group XB, pseudogene
involved_in
IDA
(PMID:12021277)
UniProt
PMID:12021277
NCBI chr16:14,709,058...14,742,495
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PLA2G12B
phospholipase A2 group XIIB
acts_upstream_of_or_within
ISO
(PMID:27471003)
MGI
PMID:27471003
NCBI chr10:72,934,762...72,954,806
Ensembl chr10:72,934,762...72,954,806
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PLA2G2A
phospholipase A2 group IIA
involved_in
TAS
(PMID:18827909)
BHF-UCL
PMID:18827909
NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416
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PLA2G2E
phospholipase A2 group IIE
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:24910243)
Ensembl MGI
PMID:24910243
GO_REF:0000107
NCBI chr 1:19,920,009...19,923,617
Ensembl chr 1:19,920,009...19,923,617
G
PLA2G3
phospholipase A2 group III
involved_in
IDA
(PMID:18801741)
UniProt
PMID:18801741
NCBI chr22:31,134,807...31,140,508
Ensembl chr22:31,134,807...31,140,508
G
PLA2G5
phospholipase A2 group V
involved_in acts_upstream_of_or_within
ISS ISO
(PMID:24910243)
UniProt MGI
PMID:24910243
GO_REF:0000024
NCBI chr 1:20,028,408...20,091,911
Ensembl chr 1:20,028,179...20,091,911
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PLA2G7
phospholipase A2 group VII
involved_in
IDA
(PMID:8624782)
BHF-UCL
PMID:8624782
NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693
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