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ONTOLOGY REPORT - ANNOTATIONS


Term:low-density lipoprotein particle remodeling
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Accession:GO:0034374 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.
Synonyms:exact_synonym: LDL remodeling;   LDL remodelling;   low-density lipoprotein particle remodelling
 related_synonym: small dense LDL formation;   small dense low-density lipoprotein particle formation



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low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in IEA
ISS
(PMID:16556852) Ensembl
BHF-UCL
PMID:16556852 GO_REF:0000107 NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,304,389
JBrowse link
G AGT angiotensinogen involved_in NAS (PMID:17069818) BHF-UCL PMID:17069818 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G AGTR1 angiotensin II receptor type 1 involved_in NAS (PMID:17069818) BHF-UCL PMID:17069818 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
JBrowse link
G APOA2 apolipoprotein A2 involved_in IDA (PMID:8106353) BHF-UCL PMID:8106353 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,290...161,223,631
JBrowse link
G APOB apolipoprotein B involved_in IMP (PMID:15797858) BHF-UCL PMID:15797858 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G CETP cholesteryl ester transfer protein involved_in IDA
IBA
(PMID:2833496) BHF-UCL
GO_Central
PMID:2833496 GO_REF:0000033 NCBI chr16:56,961,950...56,983,845
Ensembl chr16:56,961,923...56,983,845
JBrowse link
G LIPC lipase C, hepatic type involved_in ISO
IMP
(PMID:3244012) RGD
BHF-UCL
PMID:3244012 PMID:8071607 RGD:2308769 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844
JBrowse link
G MPO myeloperoxidase involved_in IDA (PMID:10772654) BHF-UCL PMID:10772654 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MTTP microsomal triglyceride transfer protein involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:27471003) Ensembl
MGI
PMID:27471003 GO_REF:0000107 NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997
JBrowse link
G PLA2G10 phospholipase A2 group X involved_in IDA (PMID:12021277) UniProt PMID:12021277 NCBI chr16:14,672,548...14,701,850
Ensembl chr16:14,672,548...14,694,308
JBrowse link
G PLA2G10BP phospholipase A2 group XB, pseudogene involved_in IDA (PMID:12021277) UniProt PMID:12021277 NCBI chr16:14,709,058...14,742,495 JBrowse link
G PLA2G12B phospholipase A2 group XIIB acts_upstream_of_or_within ISO (PMID:27471003) MGI PMID:27471003 NCBI chr10:72,934,762...72,954,806
Ensembl chr10:72,934,762...72,954,806
JBrowse link
G PLA2G2A phospholipase A2 group IIA involved_in TAS (PMID:18827909) BHF-UCL PMID:18827909 NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416
JBrowse link
G PLA2G2E phospholipase A2 group IIE involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24910243) Ensembl
MGI
PMID:24910243 GO_REF:0000107 NCBI chr 1:19,920,009...19,923,617
Ensembl chr 1:19,920,009...19,923,617
JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IDA (PMID:18801741) UniProt PMID:18801741 NCBI chr22:31,134,807...31,140,508
Ensembl chr22:31,134,807...31,140,508
JBrowse link
G PLA2G5 phospholipase A2 group V involved_in
acts_upstream_of_or_within
ISS
ISO
(PMID:24910243) UniProt
MGI
PMID:24910243 GO_REF:0000024 NCBI chr 1:20,028,408...20,091,911
Ensembl chr 1:20,028,179...20,091,911
JBrowse link
G PLA2G7 phospholipase A2 group VII involved_in IDA (PMID:8624782) BHF-UCL PMID:8624782 NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19696
    multicellular organismal process 8519
      plasma lipoprotein particle organization 55
        plasma lipoprotein particle remodeling 36
          low-density lipoprotein particle remodeling 18
Path 2
Term Annotations click to browse term
  biological_process 19696
    cellular process 18947
      cellular component organization or biogenesis 7835
        cellular component organization 7612
          protein-containing complex organization 2148
            protein-containing complex remodeling 38
              protein-lipid complex remodeling 36
                plasma lipoprotein particle remodeling 36
                  low-density lipoprotein particle remodeling 18
paths to the root