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ONTOLOGY REPORT - ANNOTATIONS

Term:very-low-density lipoprotein particle remodeling
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Accession:GO:0034372 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
Synonyms:exact_synonym: VLDL remodeling
 related_synonym: IDL formation;   intermediate-density lipoprotein particle formation

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very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,098,683...2,101,127
Ensembl chrNW_004936542:2,098,683...2,101,127 		JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:15654758)
(PMID:12401887)
(MGI:3850619|PMID:15654758)		 BHF-UCL PMID:12401887 PMID:15654758 MGI:3850619 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Cetp cholesteryl ester transfer protein involved_in IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chrNW_004936475:9,115,126...9,133,071
Ensembl chrNW_004936475:9,115,120...9,133,073 		JBrowse link
G Lcat lecithin-cholesterol acyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:18,294,013...18,297,433
Ensembl chrNW_004936475:18,293,716...18,298,248 		JBrowse link
G Lipc lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:6791934 GO_REF:0000107 RGD:2308780 NCBI chrNW_004936471:19,604,083...19,733,721
Ensembl chrNW_004936471:19,703,236...19,733,686 		JBrowse link
G Lpl lipoprotein lipase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936555:4,084,099...4,108,219
Ensembl chrNW_004936555:4,084,099...4,108,365 		JBrowse link
negative regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,111,055...2,112,626
Ensembl chrNW_004936542:2,111,052...2,112,854 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936903:520,420...521,726
Ensembl chrNW_004936903:520,650...521,910 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,106,927...2,108,412
Ensembl chrNW_004936542:2,106,318...2,108,603 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1 group H member 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6095248|PMID:27471003)
(PMID:27471003)		 MGI
Ensembl		 PMID:27471003 GO_REF:0000107 MGI:6095248 NCBI chrNW_004936492:13,315,265...13,365,186
Ensembl chrNW_004936492:13,315,265...13,374,034 		JBrowse link
positive regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa5 apolipoprotein A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,069,683...2,071,344
Ensembl chrNW_004936542:2,069,683...2,071,353 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15030
    multicellular organismal process 7336
      plasma lipoprotein particle organization 41
        plasma lipoprotein particle remodeling 28
          triglyceride-rich lipoprotein particle remodeling 11
            very-low-density lipoprotein particle remodeling 11
              negative regulation of very-low-density lipoprotein particle remodeling 4
              positive regulation of very-low-density lipoprotein particle remodeling 1
              regulation of very-low-density lipoprotein particle remodeling + 5
Path 2
Term Annotations click to browse term
  biological_process 15030
    cellular process 13409
      cellular component organization or biogenesis 5808
        cellular component organization 5644
          protein-containing complex organization 1975
            protein-containing complex remodeling 29
              protein-lipid complex remodeling 28
                plasma lipoprotein particle remodeling 28
                  triglyceride-rich lipoprotein particle remodeling 11
                    very-low-density lipoprotein particle remodeling 11
                      negative regulation of very-low-density lipoprotein particle remodeling 4
                      positive regulation of very-low-density lipoprotein particle remodeling 1
                      regulation of very-low-density lipoprotein particle remodeling + 5
paths to the root