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ONTOLOGY REPORT - ANNOTATIONS


Term:very-low-density lipoprotein particle remodeling
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Accession:GO:0034372 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
Synonyms:exact_synonym: VLDL remodeling
 related_synonym: IDL formation;   intermediate-density lipoprotein particle formation



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very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,393...44,218,978
JBrowse link
G APOA4 apolipoprotein A4 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 9:44,201,587...44,204,072
Ensembl chr 9:44,201,508...44,204,206
JBrowse link
G APOA5 apolipoprotein A5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:44,177,834...44,180,880 JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,259...51,377,794
JBrowse link
G LCAT lecithin-cholesterol acyltransferase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:28,550,356...28,553,561
Ensembl chr 6:28,550,357...28,553,567
JBrowse link
G LIPC lipase C, hepatic type involved_in ISO
IEA
RGD
Ensembl
Ensembl
PMID:6791934 GO_REF:0000107 RGD:2308780 NCBI chr 1:113,433,684...113,604,139
Ensembl chr 1:113,433,679...113,604,306
JBrowse link
G LPL lipoprotein lipase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:4,104,761...4,134,964
Ensembl chr14:4,104,772...4,135,814
JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:51,317,386...51,358,665 JBrowse link
negative regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,393...44,218,978
JBrowse link
G APOA2 apolipoprotein A2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:89,237,514...89,239,126
Ensembl chr 4:89,237,511...89,240,320
JBrowse link
G APOC3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:44,211,171...44,213,538 JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6095248|PMID:27471003)
(PMID:27471003)
MGI
Ensembl
Ensembl
PMID:27471003 GO_REF:0000107 MGI:6095248 NCBI chr 5:83,607,222...83,732,668
Ensembl chr 5:83,604,288...83,684,604
JBrowse link
positive regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA5 apolipoprotein A5 involved_in ISO (PMID:18635818) BHF-UCL PMID:18635818 NCBI chr 9:44,177,834...44,180,880 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17269
    multicellular organismal process 8458
      plasma lipoprotein particle organization 41
        plasma lipoprotein particle remodeling 27
          triglyceride-rich lipoprotein particle remodeling 11
            very-low-density lipoprotein particle remodeling 11
              negative regulation of very-low-density lipoprotein particle remodeling 4
              positive regulation of very-low-density lipoprotein particle remodeling 1
              regulation of very-low-density lipoprotein particle remodeling + 5
Path 2
Term Annotations click to browse term
  biological_process 17269
    cellular process 16298
      cellular component organization or biogenesis 6282
        cellular component organization 6098
          protein-containing complex organization 1688
            protein-containing complex remodeling 28
              protein-lipid complex remodeling 27
                plasma lipoprotein particle remodeling 27
                  triglyceride-rich lipoprotein particle remodeling 11
                    very-low-density lipoprotein particle remodeling 11
                      negative regulation of very-low-density lipoprotein particle remodeling 4
                      positive regulation of very-low-density lipoprotein particle remodeling 1
                      regulation of very-low-density lipoprotein particle remodeling + 5
paths to the root