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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:very-low-density lipoprotein particle remodeling
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Accession:GO:0034372 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
Synonyms:exact_synonym: VLDL remodeling
 related_synonym: IDL formation;   intermediate-density lipoprotein particle formation



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very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A-IV involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757
JBrowse link
G Apoa5 apolipoprotein A-V involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:46,179,906...46,183,219
Ensembl chr 9:46,179,931...46,183,217
JBrowse link
G Apoe apolipoprotein E involved_in ISO
IMP
(MGI:3850619|PMID:15654758) MGI
BHF-UCL
PMID:15654758 GO_REF:0000096 MGI:3850619 MGI:4834177 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
JBrowse link
G Lcat lecithin cholesterol acyltransferase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:106,666,183...106,670,034
Ensembl chr 8:106,666,183...106,670,014
JBrowse link
G Lipc lipase, hepatic involved_in ISO MGI
RGD
PMID:6791934 GO_REF:0000096 MGI:4417868 MGI:4834177 RGD:2308780 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508
JBrowse link
G Lpl lipoprotein lipase involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
JBrowse link
negative regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A-I involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
JBrowse link
G Apoa2 apolipoprotein A-II involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948
JBrowse link
G Apoc3 apolipoprotein C-III involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 acts_upstream_of_or_within ISO
IDA
(MGI:6095248|PMID:27471003) MGI PMID:27471003 MGI:6095248 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447
JBrowse link
positive regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa5 apolipoprotein A-V involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:46,179,906...46,183,219
Ensembl chr 9:46,179,931...46,183,217
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28778
    multicellular organismal process 9347
      plasma lipoprotein particle organization 44
        plasma lipoprotein particle remodeling 28
          triglyceride-rich lipoprotein particle remodeling 11
            very-low-density lipoprotein particle remodeling 10
              negative regulation of very-low-density lipoprotein particle remodeling 4
              positive regulation of very-low-density lipoprotein particle remodeling 1
              regulation of very-low-density lipoprotein particle remodeling + 5
Path 2
Term Annotations click to browse term
  biological_process 28778
    cellular process 16722
      cellular component organization or biogenesis 6820
        cellular component organization 6607
          protein-containing complex organization 2304
            protein-containing complex remodeling 30
              protein-lipid complex remodeling 28
                plasma lipoprotein particle remodeling 28
                  triglyceride-rich lipoprotein particle remodeling 11
                    very-low-density lipoprotein particle remodeling 10
                      negative regulation of very-low-density lipoprotein particle remodeling 4
                      positive regulation of very-low-density lipoprotein particle remodeling 1
                      regulation of very-low-density lipoprotein particle remodeling + 5
paths to the root