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ONTOLOGY REPORT - ANNOTATIONS

Term:very-low-density lipoprotein particle remodeling
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Accession:GO:0034372 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
Synonyms:exact_synonym: VLDL remodeling
 related_synonym: IDL formation;   intermediate-density lipoprotein particle formation


show annotations for term's descendants           Sort by:
very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 involved_in IBA
IDA		 (PMID:21873635)
(PMID:2307668)		 GO_Central
BHF-UCL		 PMID:2307668 PMID:21873635 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304 		JBrowse link
G APOA5 apolipoprotein A5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:116,789,367...116,792,420
Ensembl chr11:116,789,367...116,792,420 		JBrowse link
G APOC2 apolipoprotein C2 involved_in TAS (PMID:15778093) BHF-UCL PMID:15778093 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,946,035...44,949,565 		JBrowse link
G APOE apolipoprotein E involved_in IEA
IDA
IGI		 (PMID:15654758)
(PMID:12401887)		 Ensembl
BHF-UCL		 PMID:12401887 PMID:15654758 GO_REF:0000107 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G CETP cholesteryl ester transfer protein involved_in IDA
IEA
IBA		 (PMID:24293641), (PMID:2833496)
(PMID:21873635)		 BHF-UCL
UniProt
GO_Central		 PMID:2833496 PMID:21873635 PMID:24293641 GO_REF:0000104 NCBI chr16:56,961,950...56,983,845
Ensembl chr16:56,961,923...56,983,845 		JBrowse link
G LCAT lecithin-cholesterol acyltransferase involved_in IDA (PMID:15654758) BHF-UCL PMID:15654758 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131 		JBrowse link
G LIPC lipase C, hepatic type involved_in ISO
IDA		 (PMID:8640403) RGD
BHF-UCL		 PMID:6791934 PMID:8640403 RGD:2308780 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844 		JBrowse link
G LPL lipoprotein lipase involved_in ISS
IDA		 (PMID:3973011) BHF-UCL PMID:3973011 GO_REF:0000024 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259 		JBrowse link
negative regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in IDA (PMID:14967812) BHF-UCL PMID:14967812 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G APOA2 apolipoprotein A2 involved_in IDA (PMID:14967812) BHF-UCL PMID:14967812 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631 		JBrowse link
G APOC3 apolipoprotein C3 involved_in IC
IDA		 (PMID:18635818)
(PMID:3973011)		 BHF-UCL PMID:3973011 PMID:18635818 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in
acts_upstream_of_or_within		 IEA
IDA		 (PMID:27471003) Ensembl
MGI		 PMID:27471003 GO_REF:0000107 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
positive regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA5 apolipoprotein A5 involved_in IDA (PMID:18635818) BHF-UCL PMID:18635818 NCBI chr11:116,789,367...116,792,420
Ensembl chr11:116,789,367...116,792,420 		JBrowse link
G APOC2 apolipoprotein C2 involved_in IC (PMID:10727238) BHF-UCL PMID:10727238 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,946,035...44,949,565 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19532
    multicellular organismal process 8802
      plasma lipoprotein particle organization 51
        plasma lipoprotein particle remodeling 32
          triglyceride-rich lipoprotein particle remodeling 12
            very-low-density lipoprotein particle remodeling 12
              negative regulation of very-low-density lipoprotein particle remodeling 4
              positive regulation of very-low-density lipoprotein particle remodeling 2
              regulation of very-low-density lipoprotein particle remodeling + 6
Path 2
Term Annotations click to browse term
  biological_process 19532
    cellular process 16835
      cellular component organization or biogenesis 7298
        cellular component organization 7089
          protein-containing complex organization 2663
            protein-containing complex remodeling 34
              protein-lipid complex remodeling 32
                plasma lipoprotein particle remodeling 32
                  triglyceride-rich lipoprotein particle remodeling 12
                    very-low-density lipoprotein particle remodeling 12
                      negative regulation of very-low-density lipoprotein particle remodeling 4
                      positive regulation of very-low-density lipoprotein particle remodeling 2
                      regulation of very-low-density lipoprotein particle remodeling + 6
paths to the root