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ONTOLOGY REPORT - ANNOTATIONS


Term:very-low-density lipoprotein particle remodeling
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Accession:GO:0034372 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
Synonyms:exact_synonym: VLDL remodeling
 related_synonym: IDL formation;   intermediate-density lipoprotein particle formation



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very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:16,740,071...16,742,081
Ensembl chr 5:16,740,130...16,741,943
JBrowse link
G APOA4 apolipoprotein A4 involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 5:16,751,588...16,754,215
Ensembl chr 5:16,751,799...16,754,837
JBrowse link
G APOA5 apolipoprotein A5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:16,774,117...16,777,535
Ensembl chr 5:16,774,501...16,777,768
JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
G LCAT lecithin-cholesterol acyltransferase involved_in ISO (PMID:15654758) BHF-UCL PMID:15654758 NCBI chr 5:81,556,047...81,559,313 JBrowse link
G LIPC lipase C, hepatic type involved_in ISO
IEA
RGD
Ensembl
PMID:6791934 GO_REF:0000107 RGD:2308780 NCBI chr30:23,432,460...23,584,037
Ensembl chr30:23,432,493...23,584,037
JBrowse link
G LPL lipoprotein lipase involved_in ISO (PMID:3973011) BHF-UCL PMID:3973011 NCBI chr25:37,078,306...37,102,729
Ensembl chr25:37,079,756...37,102,700
JBrowse link
negative regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:16,740,071...16,742,081
Ensembl chr 5:16,740,130...16,741,943
JBrowse link
G APOA2 apolipoprotein A2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr38:21,263,641...21,265,887
Ensembl chr38:21,262,789...21,265,887
JBrowse link
G APOC3 apolipoprotein C3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:16,744,423...16,746,992
Ensembl chr 5:16,744,423...16,746,992
JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 acts_upstream_of_or_within ISO (MGI:6095248|PMID:27471003)
(PMID:27471003)
MGI PMID:27471003 MGI:6095248 NCBI chr15:39,497,313...39,608,120
Ensembl chr15:39,536,290...39,608,116
JBrowse link
positive regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA5 apolipoprotein A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:16,774,117...16,777,535
Ensembl chr 5:16,774,501...16,777,768
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16442
    multicellular organismal process 7792
      plasma lipoprotein particle organization 41
        plasma lipoprotein particle remodeling 27
          triglyceride-rich lipoprotein particle remodeling 10
            very-low-density lipoprotein particle remodeling 10
              negative regulation of very-low-density lipoprotein particle remodeling 4
              positive regulation of very-low-density lipoprotein particle remodeling 1
              regulation of very-low-density lipoprotein particle remodeling + 5
Path 2
Term Annotations click to browse term
  biological_process 16442
    cellular process 15494
      cellular component organization or biogenesis 6205
        cellular component organization 6034
          protein-containing complex organization 1679
            protein-containing complex remodeling 29
              protein-lipid complex remodeling 27
                plasma lipoprotein particle remodeling 27
                  triglyceride-rich lipoprotein particle remodeling 10
                    very-low-density lipoprotein particle remodeling 10
                      negative regulation of very-low-density lipoprotein particle remodeling 4
                      positive regulation of very-low-density lipoprotein particle remodeling 1
                      regulation of very-low-density lipoprotein particle remodeling + 5
paths to the root