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ONTOLOGY REPORT - ANNOTATIONS


Term:very-low-density lipoprotein particle remodeling
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Accession:GO:0034372 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
Synonyms:exact_synonym: VLDL remodeling
 related_synonym: IDL formation;   intermediate-density lipoprotein particle formation



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very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa4 apolipoprotein A4 involved_in ISO
IEA
IBA
(PMID:2307668)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:2307668 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoa5 apolipoprotein A5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Apoe apolipoprotein E involved_in IEA
ISO
GO_REF:0000107
(MGI:3850619|PMID:15654758)
UniProtKB:P08226 (PMID:12401887), (PMID:15654758)
Ensembl
RGD
PMID:12401887 PMID:15654758 GO_REF:0000107 MGI:3850619 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Lcat lecithin cholesterol acyltransferase involved_in ISO (PMID:15654758) RGD PMID:15654758 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lipc lipase C, hepatic type involved_in IDA
IEA
ISO
GO_REF:0000107
(PMID:8640403)
Ensembl
RGD
PMID:8640403 PMID:6791934 GO_REF:0000107, RGD:2308780 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lpl lipoprotein lipase involved_in ISO (PMID:3973011) RGD PMID:3973011 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
negative regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07070085.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Apoa1 apolipoprotein A1 involved_in ISO (PMID:14967812) RGD PMID:14967812 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:14967812) RGD PMID:14967812 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:3973011) RGD PMID:3973011 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6095248|PMID:27471003)
GO_REF:0000107
(PMID:27471003)
RGD
Ensembl
PMID:27471003 GO_REF:0000107 MGI:6095248 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
positive regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa5 apolipoprotein A5 involved_in ISO
IEA
(PMID:18635818)
GO_REF:0000107
RGD
Ensembl
PMID:18635818 GO_REF:0000107 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    multicellular organismal process 8861
      plasma lipoprotein particle organization 42
        plasma lipoprotein particle remodeling 28
          triglyceride-rich lipoprotein particle remodeling 11
            very-low-density lipoprotein particle remodeling 11
              negative regulation of very-low-density lipoprotein particle remodeling 5
              positive regulation of very-low-density lipoprotein particle remodeling 1
              regulation of very-low-density lipoprotein particle remodeling + 6
Path 2
Term Annotations click to browse term
  biological_process 18734
    cellular process 17431
      cellular component organization or biogenesis 6532
        cellular component organization 6307
          protein-containing complex organization 1761
            protein-containing complex remodeling 30
              protein-lipid complex remodeling 28
                plasma lipoprotein particle remodeling 28
                  triglyceride-rich lipoprotein particle remodeling 11
                    very-low-density lipoprotein particle remodeling 11
                      negative regulation of very-low-density lipoprotein particle remodeling 5
                      positive regulation of very-low-density lipoprotein particle remodeling 1
                      regulation of very-low-density lipoprotein particle remodeling + 6
paths to the root