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ONTOLOGY REPORT - ANNOTATIONS

Term:plasma lipoprotein particle remodeling
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Accession:GO:0034369 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).
Synonyms:exact_synonym: plasma lipoprotein particle remodelling

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plasma lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:10978346) BHF-UCL PMID:10978346 NCBI chrNW_004936706:1,519,248...1,520,102 JBrowse link
chylomicron remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipc lipase C, hepatic type ISO RGD PMID:7897313 RGD:2308767 NCBI chrNW_004936471:19,604,083...19,733,721
Ensembl chrNW_004936471:19,703,236...19,733,686 		JBrowse link
G Lpl lipoprotein lipase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936555:4,084,099...4,108,219
Ensembl chrNW_004936555:4,084,099...4,108,365 		JBrowse link
high-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca5 ATP binding cassette subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936541:8,467,035...8,549,893
Ensembl chrNW_004936541:8,463,436...8,539,942 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936500:1,620,763...1,678,561
Ensembl chrNW_004936500:1,620,641...1,678,607 		JBrowse link
G Apoa1 apolipoprotein A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,111,055...2,112,626
Ensembl chrNW_004936542:2,111,052...2,112,854 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936903:520,420...521,726
Ensembl chrNW_004936903:520,650...521,910 		JBrowse link
G Apoa4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,098,683...2,101,127
Ensembl chrNW_004936542:2,098,683...2,101,127 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,106,927...2,108,412
Ensembl chrNW_004936542:2,106,318...2,108,603 		JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:12401887) BHF-UCL PMID:12401887 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Apom apolipoprotein M involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936727:1,868,751...1,874,347
Ensembl chrNW_004936727:1,865,921...1,872,214 		JBrowse link
G Cetp cholesteryl ester transfer protein involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936475:9,115,126...9,133,071
Ensembl chrNW_004936475:9,115,120...9,133,073 		JBrowse link
G Lcat lecithin-cholesterol acyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:18,294,013...18,297,433
Ensembl chrNW_004936475:18,293,716...18,298,248 		JBrowse link
G Lipc lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:8157689 GO_REF:0000107 RGD:2308770 NCBI chrNW_004936471:19,604,083...19,733,721
Ensembl chrNW_004936471:19,703,236...19,733,686 		JBrowse link
G Lipg lipase G, endothelial type involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:13,406,402...13,429,833
Ensembl chrNW_004936497:13,406,357...13,429,890 		JBrowse link
G Pla2g3 phospholipase A2 group III involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936755:307,166...312,683
Ensembl chrNW_004936755:306,313...312,683 		JBrowse link
G Pltp phospholipid transfer protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936514:7,121,023...7,131,475 JBrowse link
G Scarb1 scavenger receptor class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:530,828...555,098
Ensembl chrNW_004936558:530,828...552,892 		JBrowse link
low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936500:1,620,763...1,678,561
Ensembl chrNW_004936500:1,620,641...1,678,607 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936903:520,420...521,726
Ensembl chrNW_004936903:520,650...521,910 		JBrowse link
G Apob apolipoprotein B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936493:10,509,118...10,549,144
Ensembl chrNW_004936493:10,509,118...10,549,144 		JBrowse link
G Apoe apolipoprotein E involved_in ISO (MGI:3850619|PMID:15654758) BHF-UCL PMID:15654758 MGI:3850619 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Cetp cholesteryl ester transfer protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936475:9,115,126...9,133,071
Ensembl chrNW_004936475:9,115,120...9,133,073 		JBrowse link
G Lipc lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:8071607 GO_REF:0000107 RGD:2308769 NCBI chrNW_004936471:19,604,083...19,733,721
Ensembl chrNW_004936471:19,703,236...19,733,686 		JBrowse link
G LOC101960864 group 10 secretory phospholipase A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:2,841,209...2,857,570
Ensembl chrNW_004936501:2,841,660...2,854,952 		JBrowse link
G Mpo myeloperoxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:4,809,773...4,819,070
Ensembl chrNW_004936490:4,809,631...4,819,070 		JBrowse link
G Mttp microsomal triglyceride transfer protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27471003) Ensembl
MGI		 PMID:27471003 GO_REF:0000107 NCBI chrNW_004936520:3,337,726...3,417,818
Ensembl chrNW_004936520:3,338,881...3,381,627 		JBrowse link
G Pla2g12b phospholipase A2 group XIIB acts_upstream_of_or_within ISO (PMID:27471003) MGI PMID:27471003 NCBI chrNW_004936521:6,072,487...6,096,791
Ensembl chrNW_004936521:6,072,486...6,096,791 		JBrowse link
G PLA2G2E phospholipase A2 group IIE involved_in IEA Ensembl GO_REF:0000107 Ensembl chrNW_004936474:6,016,541...6,020,120 JBrowse link
G Pla2g3 phospholipase A2 group III involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936755:307,166...312,683
Ensembl chrNW_004936755:306,313...312,683 		JBrowse link
G Pla2g5 phospholipase A2 group V involved_in
acts_upstream_of_or_within		 ISO (MGI:6393145|PMID:14962950)
(PMID:14962950)
(PMID:24910243)		 UniProt
MGI		 PMID:14962950 PMID:24910243 MGI:6393145 NCBI chrNW_004936474:6,131,915...6,150,810
Ensembl chrNW_004936474:6,131,884...6,150,819 		JBrowse link
G Pla2g7 phospholipase A2 group VII involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:13,609,847...13,646,174
Ensembl chrNW_004936476:13,609,374...13,649,998 		JBrowse link
negative regulation of plasma lipoprotein oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,098,683...2,101,127
Ensembl chrNW_004936542:2,098,683...2,101,127 		JBrowse link
G Apom apolipoprotein M involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:1,868,751...1,874,347
Ensembl chrNW_004936727:1,865,921...1,872,214 		JBrowse link
G Pon1 paraoxonase 1 NOT|involved_in ISO (PMID:15342686) BHF-UCL PMID:15342686 NCBI chrNW_004936585:4,954,871...4,979,560
Ensembl chrNW_004936585:4,954,869...4,979,591 		JBrowse link
negative regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,111,055...2,112,626
Ensembl chrNW_004936542:2,111,052...2,112,854 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936903:520,420...521,726
Ensembl chrNW_004936903:520,650...521,910 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,106,927...2,108,412
Ensembl chrNW_004936542:2,106,318...2,108,603 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1 group H member 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:27471003) MGI
Ensembl		 PMID:27471003 GO_REF:0000107 NCBI chrNW_004936492:13,315,265...13,365,186
Ensembl chrNW_004936492:13,315,265...13,374,034 		JBrowse link
plasma lipoprotein particle oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g7 phospholipase A2 group VII involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:13,609,847...13,646,174
Ensembl chrNW_004936476:13,609,374...13,649,998 		JBrowse link
positive regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa5 apolipoprotein A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,069,683...2,071,344
Ensembl chrNW_004936542:2,069,683...2,071,353 		JBrowse link
triglyceride-rich lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936903:520,420...521,726
Ensembl chrNW_004936903:520,650...521,910 		JBrowse link
G Apoa5 apolipoprotein A5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16166565) Ensembl
MGI		 PMID:16166565 GO_REF:0000107 NCBI chrNW_004936542:2,069,683...2,071,344
Ensembl chrNW_004936542:2,069,683...2,071,353 		JBrowse link
very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936542:2,098,683...2,101,127
Ensembl chrNW_004936542:2,098,683...2,101,127 		JBrowse link
G Apoa5 apolipoprotein A5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936542:2,069,683...2,071,344
Ensembl chrNW_004936542:2,069,683...2,071,353 		JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:15654758)
(MGI:3850619|PMID:15654758)
(PMID:12401887)		 BHF-UCL PMID:12401887 PMID:15654758 MGI:3850619 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Cetp cholesteryl ester transfer protein involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936475:9,115,126...9,133,071
Ensembl chrNW_004936475:9,115,120...9,133,073 		JBrowse link
G Lcat lecithin-cholesterol acyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:18,294,013...18,297,433
Ensembl chrNW_004936475:18,293,716...18,298,248 		JBrowse link
G Lipc lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:6791934 GO_REF:0000107 RGD:2308780 NCBI chrNW_004936471:19,604,083...19,733,721
Ensembl chrNW_004936471:19,703,236...19,733,686 		JBrowse link
G Lpl lipoprotein lipase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936555:4,084,099...4,108,219
Ensembl chrNW_004936555:4,084,099...4,108,365 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16138
    multicellular organismal process 7438
      plasma lipoprotein particle organization 41
        plasma lipoprotein particle remodeling 28
          high-density lipoprotein particle remodeling + 15
          low-density lipoprotein particle remodeling 14
          plasma lipoprotein particle oxidation + 4
          triglyceride-rich lipoprotein particle remodeling + 11
Path 2
Term Annotations click to browse term
  biological_process 16138
    cellular process 15774
      cellular component organization or biogenesis 6516
        cellular component organization 6319
          protein-containing complex organization 1711
            protein-containing complex remodeling 31
              protein-lipid complex remodeling 28
                plasma lipoprotein particle remodeling 28
                  high-density lipoprotein particle remodeling + 15
                  low-density lipoprotein particle remodeling 14
                  plasma lipoprotein particle oxidation + 4
                  triglyceride-rich lipoprotein particle remodeling + 11
paths to the root