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ONTOLOGY REPORT - ANNOTATIONS

Term:plasma lipoprotein particle remodeling
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Accession:GO:0034369 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).

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plasma lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:10978346) BHF-UCL PMID:10978346 NCBI chrNW_004936706:1,519,248...1,520,102 JBrowse link
chylomicron remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipc lipase C, hepatic type ISO RGD PMID:7897313 RGD:2308767 NCBI chrNW_004936471:19,604,083...19,733,721 JBrowse link
G Lpl lipoprotein lipase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936555:4,084,099...4,108,219 JBrowse link
high-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca5 ATP binding cassette subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936541:8,467,035...8,549,893 JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936500:1,620,763...1,678,561 JBrowse link
G Apoa1 apolipoprotein A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,111,055...2,112,626 JBrowse link
G Apoa2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936903:520,420...521,726 JBrowse link
G Apoa4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,098,683...2,101,127 JBrowse link
G Apoc3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,106,927...2,108,412 JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:12401887) BHF-UCL PMID:12401887 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Apom apolipoprotein M involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:1,868,751...1,874,347 JBrowse link
G Lcat lecithin-cholesterol acyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:18,294,013...18,297,433 JBrowse link
G Lipc lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:8157689 GO_REF:0000107 RGD:2308770 NCBI chrNW_004936471:19,604,083...19,733,721 JBrowse link
G Lipg lipase G, endothelial type involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:13,406,402...13,429,833 JBrowse link
G LOC101971021 phospholipid transfer protein involved_in ISO (PMID:24369175), (PMID:29883800), (PMID:9132017) AgBase PMID:9132017 PMID:24369175 PMID:29883800 NCBI chrNW_004936514:7,121,023...7,131,475 JBrowse link
G LOC101978543 cholesteryl ester transfer protein involved_in IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chrNW_004936475:9,115,126...9,133,071 JBrowse link
G Pla2g3 phospholipase A2 group III involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936755:307,166...312,683 JBrowse link
G Scarb1 scavenger receptor class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:530,828...555,098 JBrowse link
low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936500:1,620,763...1,678,561 JBrowse link
G Apoa2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936903:520,420...521,726 JBrowse link
G Apob apolipoprotein B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936493:10,509,118...10,549,144 JBrowse link
G Apoe apolipoprotein E involved_in ISO (MGI:3850619|PMID:15654758) BHF-UCL PMID:15654758 MGI:3850619 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Lipc lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:8071607 GO_REF:0000107 RGD:2308769 NCBI chrNW_004936471:19,604,083...19,733,721 JBrowse link
G LOC101960864 group 10 secretory phospholipase A2 involved_in ISO (PMID:12021277) UniProt PMID:12021277 NCBI chrNW_004936501:2,841,209...2,857,570 JBrowse link
G LOC101968913 microsomal triglyceride transfer protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6095248|PMID:27471003) MGI
Ensembl		 PMID:27471003 GO_REF:0000107 MGI:6095248 NCBI chrNW_004936520:3,337,726...3,417,818 JBrowse link
G LOC101978543 cholesteryl ester transfer protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:9,115,126...9,133,071 JBrowse link
G Mpo myeloperoxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:4,809,773...4,819,070 JBrowse link
G Pla2g12b phospholipase A2 group XIIB acts_upstream_of_or_within ISO (MGI:6095248|PMID:27471003) MGI PMID:27471003 MGI:6095248 NCBI chrNW_004936521:6,072,487...6,096,791 JBrowse link
G Pla2g3 phospholipase A2 group III involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936755:307,166...312,683 JBrowse link
G Pla2g5 phospholipase A2 group V involved_in
acts_upstream_of_or_within		 ISO (MGI:6393145|PMID:14962950)
(MGI:5605113|PMID:24910243)		 UniProt
MGI		 PMID:14962950 PMID:24910243 MGI:5605113 MGI:6393145 NCBI chrNW_004936474:6,131,915...6,150,810 JBrowse link
G Pla2g7 phospholipase A2 group VII involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:13,609,847...13,646,174 JBrowse link
negative regulation of plasma lipoprotein oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,098,683...2,101,127 JBrowse link
G Apom apolipoprotein M involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:1,868,751...1,874,347 JBrowse link
G Pon1 paraoxonase 1 NOT|involved_in ISO (PMID:15342686) BHF-UCL PMID:15342686 NCBI chrNW_004936585:4,954,871...4,979,560 JBrowse link
negative regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,111,055...2,112,626 JBrowse link
G Apoa2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936903:520,420...521,726 JBrowse link
G Apoc3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,106,927...2,108,412 JBrowse link
G Nr1h4 nuclear receptor subfamily 1 group H member 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6095248|PMID:27471003)
(PMID:27471003)		 MGI
Ensembl		 PMID:27471003 GO_REF:0000107 MGI:6095248 NCBI chrNW_004936492:13,315,265...13,365,186 JBrowse link
plasma lipoprotein particle oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g7 phospholipase A2 group VII involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:13,609,847...13,646,174 JBrowse link
positive regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa5 apolipoprotein A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,069,683...2,071,344 JBrowse link
triglyceride-rich lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936903:520,420...521,726 JBrowse link
G Apoa5 apolipoprotein A5 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3695062|PMID:16166565) MGI
Ensembl		 PMID:16166565 GO_REF:0000107 MGI:3695062 NCBI chrNW_004936542:2,069,683...2,071,344 JBrowse link
very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,098,683...2,101,127 JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:15654758)
(MGI:3850619|PMID:15654758)
(PMID:12401887)		 BHF-UCL PMID:12401887 PMID:15654758 MGI:3850619 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Lcat lecithin-cholesterol acyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:18,294,013...18,297,433 JBrowse link
G Lipc lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:6791934 GO_REF:0000107 RGD:2308780 NCBI chrNW_004936471:19,604,083...19,733,721 JBrowse link
G LOC101978543 cholesteryl ester transfer protein involved_in IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chrNW_004936475:9,115,126...9,133,071 JBrowse link
G Lpl lipoprotein lipase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936555:4,084,099...4,108,219 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14984
    multicellular organismal process 7061
      plasma lipoprotein particle organization 39
        plasma lipoprotein particle remodeling 27
          high-density lipoprotein particle remodeling + 15
          low-density lipoprotein particle remodeling 13
          plasma lipoprotein particle oxidation + 4
          triglyceride-rich lipoprotein particle remodeling + 11
Path 2
Term Annotations click to browse term
  biological_process 14984
    cellular process 13982
      cellular component organization or biogenesis 5557
        cellular component organization 5414
          protein-containing complex organization 1494
            protein-containing complex remodeling 28
              protein-lipid complex remodeling 27
                plasma lipoprotein particle remodeling 27
                  high-density lipoprotein particle remodeling + 15
                  low-density lipoprotein particle remodeling 13
                  plasma lipoprotein particle oxidation + 4
                  triglyceride-rich lipoprotein particle remodeling + 11
paths to the root