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ONTOLOGY REPORT - ANNOTATIONS

Term:plasma lipoprotein particle remodeling
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Accession:GO:0034369 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).
Synonyms:exact_synonym: plasma lipoprotein particle remodelling


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chylomicron remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LIPC lipase C, hepatic type ISO RGD PMID:7897313 RGD:2308767 NCBI chr 1:113,433,684...113,604,139
Ensembl chr 1:113,433,687...113,583,963 		JBrowse link
G LPL lipoprotein lipase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:4,104,761...4,134,964
Ensembl chr14:4,104,772...4,135,814 		JBrowse link
high-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA5 ATP binding cassette subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:11,018,692...11,152,916
Ensembl chr12:11,067,500...11,152,688 		JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852), (MGI:5634884|PMID:21481393) BHF-UCL PMID:16556852 PMID:21481393 MGI:3852307 MGI:5634884 NCBI chr13:205,561,897...205,628,428
Ensembl chr13:205,561,951...205,628,425 		JBrowse link
G APOA1 apolipoprotein A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,392...44,218,713 		JBrowse link
G APOA2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:89,237,514...89,239,126
Ensembl chr 4:89,237,511...89,240,319 		JBrowse link
G APOA4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:44,201,587...44,204,072
Ensembl chr 9:44,201,508...44,204,206 		JBrowse link
G APOC3 apolipoprotein C3 involved_in ISO (PMID:17438339) BHF-UCL PMID:17438339 NCBI chr 9:44,211,171...44,213,538
Ensembl chr 9:44,211,194...44,213,533 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G APOM apolipoprotein M involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:23,768,974...23,773,324
Ensembl chr 7:23,768,984...23,773,324 		JBrowse link
G LCAT lecithin-cholesterol acyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:28,550,356...28,553,561
Ensembl chr 6:28,550,358...28,553,566 		JBrowse link
G LIPC lipase C, hepatic type involved_in ISO
IEA
IBA		 RGD
Ensembl
GO_Central		 PMID:8157689 GO_REF:0000033 GO_REF:0000107 RGD:2308770 NCBI chr 1:113,433,684...113,604,139
Ensembl chr 1:113,433,687...113,583,963 		JBrowse link
G LIPG lipase G, endothelial type involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:99,081,940...99,110,671
Ensembl chr 1:99,081,938...99,110,874 		JBrowse link
G LPL lipoprotein lipase involved_in IBA GO_Central GO_REF:0000033 NCBI chr14:4,104,761...4,134,964
Ensembl chr14:4,104,772...4,135,814 		JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:47,923,005...47,928,762
Ensembl chr14:47,923,954...47,928,810 		JBrowse link
G PLTP phospholipid transfer protein involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:48,089,789...48,101,604
Ensembl chr17:48,089,785...48,101,515 		JBrowse link
G SCARB1 scavenger receptor class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:28,301,421...28,393,568
Ensembl chr14:28,301,294...28,393,568 		JBrowse link
low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852)
(PMID:16556852)		 BHF-UCL PMID:16556852 MGI:3852307 NCBI chr13:205,561,897...205,628,428
Ensembl chr13:205,561,951...205,628,425 		JBrowse link
G APOA2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:89,237,514...89,239,126
Ensembl chr 4:89,237,511...89,240,319 		JBrowse link
G APOB apolipoprotein B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:117,250,096...117,316,200
Ensembl chr 3:117,250,096...117,316,200 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G LIPC lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:8071607 GO_REF:0000107 RGD:2308769 NCBI chr 1:113,433,684...113,604,139
Ensembl chr 1:113,433,687...113,583,963 		JBrowse link
G LOC110259864 group 10 secretory phospholipase A2-like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:7,623,326...7,641,061
Ensembl chr 3:7,623,312...7,642,002 		JBrowse link
G MPO myeloperoxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:34,557,031...34,570,091
Ensembl chr12:34,556,408...34,567,904 		JBrowse link
G MTTP microsomal triglyceride transfer protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27471003) Ensembl
MGI		 PMID:27471003 GO_REF:0000107 NCBI chr 8:120,820,660...120,871,468
Ensembl chr 8:120,820,656...120,879,388 		JBrowse link
G PLA2G12B phospholipase A2 group XIIB acts_upstream_of_or_within ISO (PMID:27471003) MGI PMID:27471003 NCBI chr14:75,754,525...75,778,933
Ensembl chr14:75,753,727...75,778,800 		JBrowse link
G PLA2G2E phospholipase A2 group IIE involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24910243) Ensembl
MGI		 PMID:24910243 GO_REF:0000107 NCBI chr 6:78,278,080...78,282,253
Ensembl chr 6:78,278,284...78,282,377 		JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:47,923,005...47,928,762
Ensembl chr14:47,923,954...47,928,810 		JBrowse link
G PLA2G5 phospholipase A2 group V involved_in
acts_upstream_of_or_within		 ISO (MGI:6393145|PMID:14962950)
(PMID:14962950)
(PMID:24910243)		 UniProt
MGI		 PMID:14962950 PMID:24910243 MGI:6393145 NCBI chr 6:78,365,697...78,376,383
Ensembl chr 6:78,302,062...78,376,220 		JBrowse link
G PLA2G7 phospholipase A2 group VII involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:41,488,152...41,531,383
Ensembl chr 7:41,486,598...41,531,345 		JBrowse link
negative regulation of plasma lipoprotein oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:44,201,587...44,204,072
Ensembl chr 9:44,201,508...44,204,206 		JBrowse link
G APOM apolipoprotein M involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:23,768,974...23,773,324
Ensembl chr 7:23,768,984...23,773,324 		JBrowse link
G PON1 paraoxonase 1 NOT|involved_in ISO (PMID:15342686) BHF-UCL PMID:15342686 NCBI chr 9:74,943,646...74,974,720
Ensembl chr 9:74,926,048...74,974,723 		JBrowse link
negative regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,392...44,218,713 		JBrowse link
G APOA2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:89,237,514...89,239,126
Ensembl chr 4:89,237,511...89,240,319 		JBrowse link
G APOC3 apolipoprotein C3 involved_in ISO (PMID:3973011) BHF-UCL PMID:3973011 NCBI chr 9:44,211,171...44,213,538
Ensembl chr 9:44,211,194...44,213,533 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:27471003) MGI
Ensembl		 PMID:27471003 GO_REF:0000107 NCBI chr 5:83,607,222...83,732,668
Ensembl chr 5:83,604,294...83,684,604 		JBrowse link
plasma lipoprotein particle oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G7 phospholipase A2 group VII involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:41,488,152...41,531,383
Ensembl chr 7:41,486,598...41,531,345 		JBrowse link
positive regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA5 apolipoprotein A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:44,177,834...44,180,880
Ensembl chr 9:44,178,606...44,180,885 		JBrowse link
triglyceride-rich lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:89,237,514...89,239,126
Ensembl chr 4:89,237,511...89,240,319 		JBrowse link
G APOA5 apolipoprotein A5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16166565) Ensembl
MGI		 PMID:16166565 GO_REF:0000107 NCBI chr 9:44,177,834...44,180,880
Ensembl chr 9:44,178,606...44,180,885 		JBrowse link
very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:44,201,587...44,204,072
Ensembl chr 9:44,201,508...44,204,206 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G LCAT lecithin-cholesterol acyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:28,550,356...28,553,561
Ensembl chr 6:28,550,358...28,553,566 		JBrowse link
G LIPC lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:6791934 GO_REF:0000107 RGD:2308780 NCBI chr 1:113,433,684...113,604,139
Ensembl chr 1:113,433,687...113,583,963 		JBrowse link
G LPL lipoprotein lipase involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr14:4,104,761...4,134,964
Ensembl chr14:4,104,772...4,135,814 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17647
    multicellular organismal process 8630
      plasma lipoprotein particle organization 41
        plasma lipoprotein particle remodeling 26
          high-density lipoprotein particle remodeling + 15
          low-density lipoprotein particle remodeling 13
          plasma lipoprotein particle oxidation + 4
          triglyceride-rich lipoprotein particle remodeling + 10
Path 2
Term Annotations click to browse term
  biological_process 17647
    cellular process 17210
      cellular component organization or biogenesis 6593
        cellular component organization 6399
          protein-containing complex organization 1699
            protein-containing complex remodeling 28
              protein-lipid complex remodeling 26
                plasma lipoprotein particle remodeling 26
                  high-density lipoprotein particle remodeling + 15
                  low-density lipoprotein particle remodeling 13
                  plasma lipoprotein particle oxidation + 4
                  triglyceride-rich lipoprotein particle remodeling + 10
paths to the root