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ONTOLOGY REPORT - ANNOTATIONS

Term:plasma lipoprotein particle remodeling
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Accession:GO:0034369 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).
Synonyms:exact_synonym: plasma lipoprotein particle remodelling

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plasma lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:10978346) BHF-UCL PMID:10978346 NCBI chrNW_004624907:1,758,671...1,760,611
Ensembl chrNW_004624907:1,758,696...1,760,611 		JBrowse link
chylomicron remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipc lipase C, hepatic type ISO RGD PMID:7897313 RGD:2308767 NCBI chrNW_004624781:13,342,469...13,468,120
Ensembl chrNW_004624781:13,342,357...13,455,055 		JBrowse link
G Lpl lipoprotein lipase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624758:15,652,553...15,680,107
Ensembl chrNW_004624758:15,651,992...15,680,762 		JBrowse link
high-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca5 ATP binding cassette subfamily A member 5 involved_in ISO (MGI:4454250|PMID:20382126) BHF-UCL PMID:20382126 MGI:4454250 NCBI chrNW_004624870:4,150,287...4,224,448
Ensembl chrNW_004624870:4,153,594...4,218,132 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852), (MGI:5634884|PMID:21481393) BHF-UCL PMID:16556852 PMID:21481393 MGI:3852307 MGI:5634884 NCBI chrNW_004624745:28,137,140...28,188,670
Ensembl chrNW_004624745:28,104,744...28,188,704 		JBrowse link
G Apoa1 apolipoprotein A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:12,249,283...12,251,215
Ensembl chrNW_004624784:12,249,283...12,251,136 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624794:164,351...165,676
Ensembl chrNW_004624794:164,370...166,248 		JBrowse link
G Apoa4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:12,237,329...12,240,013
Ensembl chrNW_004624784:12,233,593...12,239,763 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:12,244,565...12,246,790
Ensembl chrNW_004624784:12,244,646...12,246,790 		JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:12401887) BHF-UCL PMID:12401887 NCBI chrNW_004624907:1,752,322...1,755,308 JBrowse link
G Apom apolipoprotein M involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624754:24,554,705...24,558,093
Ensembl chrNW_004624754:24,554,705...24,557,098 		JBrowse link
G Cetp cholesteryl ester transfer protein involved_in IEA TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004624746:29,035,282...29,053,867 JBrowse link
G Lcat lecithin-cholesterol acyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624746:18,438,308...18,441,650
Ensembl chrNW_004624746:18,437,429...18,441,806 		JBrowse link
G Lipc lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:8157689 GO_REF:0000107 RGD:2308770 NCBI chrNW_004624781:13,342,469...13,468,120
Ensembl chrNW_004624781:13,342,357...13,455,055 		JBrowse link
G Lipg lipase G, endothelial type involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624778:13,107,037...13,133,162
Ensembl chrNW_004624778:13,107,283...13,133,270 		JBrowse link
G Pla2g3 phospholipase A2 group III involved_in ISO (PMID:18801741) UniProt PMID:18801741 NCBI chrNW_004624747:7,602,848...7,607,872
Ensembl chrNW_004624747:7,603,277...7,607,753 		JBrowse link
G Pltp phospholipid transfer protein involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624790:8,673,212...8,686,094
Ensembl chrNW_004624790:8,673,089...8,685,942 		JBrowse link
G Scarb1 scavenger receptor class B member 1 involved_in ISO (MGI:3056693|PMID:15210842), (MGI:5634884|PMID:21481393) BHF-UCL PMID:15210842 PMID:21481393 MGI:3056693 MGI:5634884 NCBI chrNW_004624747:23,970,782...24,010,683
Ensembl chrNW_004624747:23,973,648...24,010,820 		JBrowse link
low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:16556852)
(MGI:3852307|PMID:16556852)		 BHF-UCL PMID:16556852 MGI:3852307 NCBI chrNW_004624745:28,137,140...28,188,670
Ensembl chrNW_004624745:28,104,744...28,188,704 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624794:164,351...165,676
Ensembl chrNW_004624794:164,370...166,248 		JBrowse link
G Apob apolipoprotein B involved_in ISO (PMID:15797858) BHF-UCL PMID:15797858 NCBI chrNW_004624738:3,579,747...3,622,508
Ensembl chrNW_004624738:3,580,033...3,620,192 		JBrowse link
G Apoe apolipoprotein E involved_in ISO (MGI:3850619|PMID:15654758) BHF-UCL PMID:15654758 MGI:3850619 NCBI chrNW_004624907:1,752,322...1,755,308 JBrowse link
G Cetp cholesteryl ester transfer protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624746:29,035,282...29,053,867 JBrowse link
G Lipc lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:8071607 GO_REF:0000107 RGD:2308769 NCBI chrNW_004624781:13,342,469...13,468,120
Ensembl chrNW_004624781:13,342,357...13,455,055 		JBrowse link
G Mpo myeloperoxidase involved_in ISO (PMID:10772654) BHF-UCL PMID:10772654 NCBI chrNW_004624871:121,026...131,433
Ensembl chrNW_004624871:121,026...131,323 		JBrowse link
G Mttp microsomal triglyceride transfer protein acts_upstream_of_or_within ISO (PMID:27471003) MGI PMID:27471003 NCBI chrNW_004624830:7,463,671...7,505,607
Ensembl chrNW_004624830:7,464,686...7,506,129 		JBrowse link
G Pla2g10 phospholipase A2 group X involved_in ISO (PMID:12021277) UniProt PMID:12021277 NCBI chrNW_004624782:3,871,034...3,887,476
Ensembl chrNW_004624782:3,870,940...3,887,426 		JBrowse link
G Pla2g12b phospholipase A2 group XIIB acts_upstream_of_or_within ISO (PMID:27471003) MGI PMID:27471003 NCBI chrNW_004624754:6,653,307...6,680,063
Ensembl chrNW_004624754:6,653,698...6,680,489 		JBrowse link
G Pla2g2e phospholipase A2 group IIE acts_upstream_of_or_within ISO (PMID:24910243) MGI PMID:24910243 NCBI chrNW_004624764:4,984,021...4,989,315
Ensembl chrNW_004624764:4,985,688...4,988,818 		JBrowse link
G Pla2g3 phospholipase A2 group III involved_in ISO (PMID:18801741) UniProt PMID:18801741 NCBI chrNW_004624747:7,602,848...7,607,872
Ensembl chrNW_004624747:7,603,277...7,607,753 		JBrowse link
G Pla2g5 phospholipase A2 group V involved_in
acts_upstream_of_or_within		 ISO (PMID:14962950)
(PMID:24910243)
(MGI:6393145|PMID:14962950)		 UniProt
MGI		 PMID:14962950 PMID:24910243 MGI:6393145 NCBI chrNW_004624764:5,196,215...5,207,138
Ensembl chrNW_004624764:5,196,215...5,207,232 		JBrowse link
G Pla2g7 phospholipase A2 group VII involved_in ISO (PMID:8624782) BHF-UCL PMID:8624782 NCBI chrNW_004624754:13,905,084...13,932,366
Ensembl chrNW_004624754:13,904,797...13,931,670 		JBrowse link
negative regulation of plasma lipoprotein oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:12,237,329...12,240,013
Ensembl chrNW_004624784:12,233,593...12,239,763 		JBrowse link
G Apom apolipoprotein M involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624754:24,554,705...24,558,093
Ensembl chrNW_004624754:24,554,705...24,557,098 		JBrowse link
G Pon1 paraoxonase 1 NOT|involved_in ISO (PMID:15342686) BHF-UCL PMID:15342686 NCBI chrNW_004624813:1,953,796...1,979,846
Ensembl chrNW_004624813:1,949,614...1,979,882 		JBrowse link
negative regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:12,249,283...12,251,215
Ensembl chrNW_004624784:12,249,283...12,251,136 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624794:164,351...165,676
Ensembl chrNW_004624794:164,370...166,248 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:12,244,565...12,246,790
Ensembl chrNW_004624784:12,244,646...12,246,790 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1 group H member 4 acts_upstream_of_or_within ISO (PMID:27471003) MGI PMID:27471003 NCBI chrNW_004624750:7,222,306...7,303,809
Ensembl chrNW_004624750:7,219,251...7,303,834 		JBrowse link
plasma lipoprotein particle oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g7 phospholipase A2 group VII involved_in ISO (PMID:8624782) BHF-UCL PMID:8624782 NCBI chrNW_004624754:13,905,084...13,932,366
Ensembl chrNW_004624754:13,904,797...13,931,670 		JBrowse link
positive regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa5 apolipoprotein A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:12,213,205...12,216,039
Ensembl chrNW_004624784:12,213,744...12,216,026 		JBrowse link
triglyceride-rich lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A2 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624794:164,351...165,676
Ensembl chrNW_004624794:164,370...166,248 		JBrowse link
G Apoa5 apolipoprotein A5 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16166565) MGI
Ensembl		 PMID:16166565 GO_REF:0000107 NCBI chrNW_004624784:12,213,205...12,216,039
Ensembl chrNW_004624784:12,213,744...12,216,026 		JBrowse link
very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A4 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624784:12,237,329...12,240,013
Ensembl chrNW_004624784:12,233,593...12,239,763 		JBrowse link
G Apoa5 apolipoprotein A5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624784:12,213,205...12,216,039
Ensembl chrNW_004624784:12,213,744...12,216,026 		JBrowse link
G Apoe apolipoprotein E involved_in ISO (MGI:3850619|PMID:15654758)
(PMID:15654758)
(PMID:12401887)		 BHF-UCL PMID:12401887 PMID:15654758 MGI:3850619 NCBI chrNW_004624907:1,752,322...1,755,308 JBrowse link
G Cetp cholesteryl ester transfer protein involved_in IEA TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004624746:29,035,282...29,053,867 JBrowse link
G Lcat lecithin-cholesterol acyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624746:18,438,308...18,441,650
Ensembl chrNW_004624746:18,437,429...18,441,806 		JBrowse link
G Lipc lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:6791934 GO_REF:0000107 RGD:2308780 NCBI chrNW_004624781:13,342,469...13,468,120
Ensembl chrNW_004624781:13,342,357...13,455,055 		JBrowse link
G Lpl lipoprotein lipase involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624758:15,652,553...15,680,107
Ensembl chrNW_004624758:15,651,992...15,680,762 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15248
    multicellular organismal process 7142
      plasma lipoprotein particle organization 41
        plasma lipoprotein particle remodeling 28
          high-density lipoprotein particle remodeling + 15
          low-density lipoprotein particle remodeling 14
          plasma lipoprotein particle oxidation + 4
          triglyceride-rich lipoprotein particle remodeling + 11
Path 2
Term Annotations click to browse term
  biological_process 15248
    cellular process 14879
      cellular component organization or biogenesis 6245
        cellular component organization 6055
          protein-containing complex organization 1635
            protein-containing complex remodeling 31
              protein-lipid complex remodeling 28
                plasma lipoprotein particle remodeling 28
                  high-density lipoprotein particle remodeling + 15
                  low-density lipoprotein particle remodeling 14
                  plasma lipoprotein particle oxidation + 4
                  triglyceride-rich lipoprotein particle remodeling + 11
paths to the root