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ONTOLOGY REPORT - ANNOTATIONS

Term:plasma lipoprotein particle remodeling
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Accession:GO:0034369 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).
Synonyms:exact_synonym: plasma lipoprotein particle remodelling


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plasma lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C-I involved_in ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr 7:19,423,405...19,426,584
Ensembl chr 7:19,423,406...19,426,585 		JBrowse link
chylomicron remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipc lipase, hepatic involved_in ISO RGD
MGI		 PMID:7897313 GO_REF:0000096 MGI:4417868 RGD:2308767 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508 		JBrowse link
G Lpl lipoprotein lipase involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100 		JBrowse link
high-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca5 ATP-binding cassette, sub-family A member 5 involved_in IMP (MGI:4454250|PMID:20382126)
(PMID:20382126)		 BHF-UCL PMID:20382126 MGI:4454250 NCBI chr11:110,160,195...110,228,542
Ensembl chr11:110,160,195...110,228,542 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in IMP (MGI:3852307|PMID:16556852), (MGI:5634884|PMID:21481393)
(PMID:16556852), (PMID:21481393)		 BHF-UCL PMID:16556852 PMID:21481393 MGI:3852307 MGI:5634884 NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962 		JBrowse link
G Apoa1 apolipoprotein A-I involved_in ISO
IEA		 MGI
Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764 		JBrowse link
G Apoa2 apolipoprotein A-II involved_in ISO
IEA		 MGI
Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948 		JBrowse link
G Apoa4 apolipoprotein A-IV involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757 		JBrowse link
G Apoc3 apolipoprotein C-III involved_in ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934 		JBrowse link
G Apoe apolipoprotein E involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Apom apolipoprotein M involved_in IMP
ISO
IBA		 (MGI:3575626|PMID:15793583)
(PMID:15793583)		 BHF-UCL
GO_Central
MGI		 PMID:15793583 GO_REF:0000033 GO_REF:0000119 MGI:3575626 MGI:4834177 NCBI chr17:35,347,973...35,350,777
Ensembl chr17:35,347,973...35,351,026 		JBrowse link
G Lcat lecithin cholesterol acyltransferase involved_in ISO
IEA		 MGI
Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 8:106,666,183...106,670,034
Ensembl chr 8:106,666,183...106,670,014 		JBrowse link
G Lipc lipase, hepatic involved_in ISO
IBA
IEA		 RGD
MGI
GO_Central
Ensembl		 PMID:8157689 GO_REF:0000033 GO_REF:0000096 GO_REF:0000107 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:2308770 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508 		JBrowse link
G Lipg lipase, endothelial involved_in ISO
IBA
IEA		 MGI
GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr18:75,072,393...75,095,380
Ensembl chr18:75,072,393...75,094,334 		JBrowse link
G Lpl lipoprotein lipase involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100 		JBrowse link
G Pla2g3 phospholipase A2, group III involved_in ISO
ISS		 MGI
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 NCBI chr11:3,438,158...3,449,346
Ensembl chr11:3,438,284...3,449,350 		JBrowse link
G Pltp phospholipid transfer protein involved_in ISO
ISS
IBA		 MGI
UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 2:164,681,441...164,699,564
Ensembl chr 2:164,681,438...164,699,631 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in IMP (MGI:3056693|PMID:15210842), (MGI:5634884|PMID:21481393) BHF-UCL PMID:15210842 PMID:21481393 MGI:3056693 MGI:5634884 NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158 		JBrowse link
low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in IMP (MGI:3852307|PMID:16556852)
(PMID:16556852)		 BHF-UCL PMID:16556852 MGI:3852307 NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962 		JBrowse link
G Apoa2 apolipoprotein A-II involved_in ISO
IEA		 MGI
GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948 		JBrowse link
G Apob apolipoprotein B involved_in ISO
IEA		 MGI
Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835 		JBrowse link
G Apoe apolipoprotein E involved_in IMP (MGI:3850619|PMID:15654758) BHF-UCL PMID:15654758 MGI:3850619 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Lipc lipase, hepatic involved_in ISO
IEA		 RGD
Ensembl
GO_Central
MGI		 PMID:8071607 GO_REF:0000096 GO_REF:0000107 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:2308769 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508 		JBrowse link
G Mpo myeloperoxidase involved_in ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Mttp microsomal triglyceride transfer protein acts_upstream_of_or_within IDA (PMID:27471003) MGI PMID:27471003 NCBI chr 3:137,795,616...137,849,179
Ensembl chr 3:137,795,615...137,850,729 		JBrowse link
G Pla2g10 phospholipase A2, group X involved_in ISO
IEA		 MGI
GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr16:13,532,921...13,548,863
Ensembl chr16:13,532,921...13,548,847 		JBrowse link
G Pla2g12b phospholipase A2, group XIIB acts_upstream_of_or_within IDA (PMID:27471003) MGI PMID:27471003 NCBI chr10:59,239,242...59,257,798
Ensembl chr10:59,239,482...59,257,798 		JBrowse link
G Pla2g2e phospholipase A2, group IIE acts_upstream_of_or_within IMP (PMID:24910243) MGI PMID:24910243 NCBI chr 4:138,605,253...138,610,125
Ensembl chr 4:138,605,253...138,610,128 		JBrowse link
G Pla2g3 phospholipase A2, group III involved_in ISO
ISS		 MGI
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 NCBI chr11:3,438,158...3,449,346
Ensembl chr11:3,438,284...3,449,350 		JBrowse link
G Pla2g5 phospholipase A2, group V involved_in
acts_upstream_of_or_within		 IDA
IMP		 (MGI:6393145|PMID:14962950)
(PMID:14962950)
(PMID:24910243)		 UniProt
MGI		 PMID:14962950 PMID:24910243 MGI:6393145 NCBI chr 4:138,526,558...138,590,784
Ensembl chr 4:138,526,555...138,590,793 		JBrowse link
G Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:43,879,009...43,923,093
Ensembl chr17:43,878,989...43,923,092 		JBrowse link
negative regulation of plasma lipoprotein oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A-IV involved_in ISO
IEA		 MGI
Ensembl		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757 		JBrowse link
G Apom apolipoprotein M involved_in IDA
ISO		 (MGI:5427066|PMID:22204862) BHF-UCL
MGI		 PMID:22204862 GO_REF:0000119 MGI:4834177 MGI:5427066 NCBI chr17:35,347,973...35,350,777
Ensembl chr17:35,347,973...35,351,026 		JBrowse link
G Pon1 paraoxonase 1 NOT|involved_in ISO (PMID:15342686) BHF-UCL PMID:15342686 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946 		JBrowse link
negative regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A-I involved_in ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764 		JBrowse link
G Apoa2 apolipoprotein A-II involved_in ISO
IEA		 MGI
Ensembl		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948 		JBrowse link
G Apoc3 apolipoprotein C-III involved_in ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 acts_upstream_of_or_within ISO
IDA		 (PMID:27471003) MGI PMID:27471003 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447 		JBrowse link
plasma lipoprotein particle oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) involved_in ISO
IEA		 MGI
Ensembl		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr17:43,879,009...43,923,093
Ensembl chr17:43,878,989...43,923,092 		JBrowse link
positive regulation of chylomicron remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpihbp1 GPI-anchored HDL-binding protein 1 involved_in IC (MGI:3770110|PMID:17403372)
(PMID:17403372)		 BHF-UCL PMID:17403372 MGI:3770110 NCBI chr15:75,468,479...75,470,062
Ensembl chr15:75,468,477...75,471,330 		JBrowse link
positive regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa5 apolipoprotein A-V involved_in ISO
IEA		 MGI
GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 9:46,179,906...46,183,219
Ensembl chr 9:46,179,931...46,183,217 		JBrowse link
triglyceride-rich lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A-II involved_in ISO
IEA		 MGI
Ensembl		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948 		JBrowse link
G Apoa5 apolipoprotein A-V acts_upstream_of_or_within IMP (PMID:16166565) MGI PMID:16166565 NCBI chr 9:46,179,906...46,183,219
Ensembl chr 9:46,179,931...46,183,217 		JBrowse link
very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A-IV involved_in ISO
IEA		 MGI
Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757 		JBrowse link
G Apoe apolipoprotein E involved_in IMP
ISO		 (MGI:3850619|PMID:15654758)
(PMID:15654758)		 BHF-UCL
GO_Central
MGI		 PMID:15654758 GO_REF:0000119 MGI:3850619 MGI:4834177 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Lcat lecithin cholesterol acyltransferase involved_in ISO
IEA		 MGI
Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 8:106,666,183...106,670,034
Ensembl chr 8:106,666,183...106,670,014 		JBrowse link
G Lipc lipase, hepatic involved_in ISO
IEA		 RGD
GO_Central
Ensembl
MGI		 PMID:6791934 GO_REF:0000096 GO_REF:0000107 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:2308780 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508 		JBrowse link
G Lpl lipoprotein lipase involved_in ISO
IEA
IBA		 MGI
GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28760
    multicellular organismal process 9050
      plasma lipoprotein particle organization 44
        plasma lipoprotein particle remodeling 28
          high-density lipoprotein particle remodeling + 15
          low-density lipoprotein particle remodeling 13
          plasma lipoprotein particle oxidation + 4
          triglyceride-rich lipoprotein particle remodeling + 11
Path 2
Term Annotations click to browse term
  biological_process 28760
    cellular process 18484
      cellular component organization or biogenesis 7212
        cellular component organization 6999
          protein-containing complex organization 1860
            protein-containing complex remodeling 31
              protein-lipid complex remodeling 28
                plasma lipoprotein particle remodeling 28
                  high-density lipoprotein particle remodeling + 15
                  low-density lipoprotein particle remodeling 13
                  plasma lipoprotein particle oxidation + 4
                  triglyceride-rich lipoprotein particle remodeling + 11
paths to the root