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ONTOLOGY REPORT - ANNOTATIONS

Term:plasma lipoprotein particle remodeling
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Accession:GO:0034369 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).
Synonyms:exact_synonym: plasma lipoprotein particle remodelling


show annotations for term's descendants           Sort by:
plasma lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC1 apolipoprotein C1 involved_in IDA (PMID:10978346) BHF-UCL PMID:10978346 NCBI chr19:44,914,325...44,919,346
Ensembl chr19:44,914,247...44,919,349 		JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme involved_in TAS Reactome Reactome:R-HSA-8963889 NCBI chr15:90,868,588...90,883,457
Ensembl chr15:90,868,588...90,883,564 		JBrowse link
G PCSK5 proprotein convertase subtilisin/kexin type 5 involved_in TAS Reactome Reactome:R-HSA-8963889 NCBI chr 9:75,889,809...76,362,975
Ensembl chr 9:75,890,644...76,362,975 		JBrowse link
G PCSK6 proprotein convertase subtilisin/kexin type 6 involved_in TAS Reactome Reactome:R-HSA-8963889 NCBI chr15:101,303,933...101,489,707
Ensembl chr15:101,289,784...101,525,202 		JBrowse link
chylomicron remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 involved_in IC (PMID:2307668) BHF-UCL PMID:2307668 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304 		JBrowse link
G APOC2 apolipoprotein C2 involved_in IC (PMID:10727238) BHF-UCL PMID:10727238 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,946,035...44,949,565 		JBrowse link
G LIPC lipase C, hepatic type ISO RGD PMID:7897313 RGD:2308767 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844 		JBrowse link
G LPL lipoprotein lipase involved_in IMP
IC		 (PMID:11342582)
(PMID:3973011)		 UniProt
BHF-UCL		 PMID:3973011 PMID:11342582 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259 		JBrowse link
high-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA5 ATP binding cassette subfamily A member 5 involved_in IEA
ISS		 (PMID:20382126) Ensembl
BHF-UCL		 PMID:20382126 GO_REF:0000107 NCBI chr17:69,244,311...69,327,133
Ensembl chr17:69,244,311...69,327,244 		JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISS
IEA		 (PMID:16556852) BHF-UCL
Ensembl		 PMID:16556852 GO_REF:0000107 NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,297,244 		JBrowse link
G APOA1 apolipoprotein A1 involved_in IDA (PMID:21481393), (PMID:4335615) BHF-UCL PMID:4335615 PMID:21481393 NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G APOA2 apolipoprotein A2 involved_in IDA (PMID:14967812), (PMID:8106353) BHF-UCL PMID:8106353 PMID:14967812 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631 		JBrowse link
G APOA4 apolipoprotein A4 involved_in IDA (PMID:1935934) BHF-UCL PMID:1935934 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304 		JBrowse link
G APOC1 apolipoprotein C1 involved_in TAS (PMID:18992221) BHF-UCL PMID:18992221 NCBI chr19:44,914,325...44,919,346
Ensembl chr19:44,914,247...44,919,349 		JBrowse link
G APOC3 apolipoprotein C3 involved_in IMP (PMID:17438339) BHF-UCL PMID:17438339 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072 		JBrowse link
G APOE apolipoprotein E involved_in IGI (PMID:12401887) BHF-UCL PMID:12401887 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G APOM apolipoprotein M involved_in IEA
IBA
IMP		 (PMID:18006500) Ensembl
GO_Central
BHF-UCL		 PMID:18006500 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:31,652,404...31,658,210
Ensembl chr 6:31,652,416...31,658,210 		JBrowse link
G CETP cholesteryl ester transfer protein involved_in IDA
IBA
IMP
IEA		 (PMID:24293641)
(PMID:2586614)		 UniProt
GO_Central
BHF-UCL		 PMID:2586614 PMID:24293641 GO_REF:0000033 GO_REF:0000104 NCBI chr16:56,961,950...56,983,845
Ensembl chr16:56,961,923...56,983,845 		JBrowse link
G LCAT lecithin-cholesterol acyltransferase involved_in IDA
TAS		 (PMID:10722751), (PMID:12167653), (PMID:15210842), (PMID:4335615) BHF-UCL
Reactome		 PMID:4335615 PMID:10722751 PMID:12167653 PMID:15210842 Reactome:R-HSA-8964058 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131 		JBrowse link
G LIPC lipase C, hepatic type involved_in ISO
IBA
IMP		 (PMID:3244012) RGD
GO_Central
BHF-UCL		 PMID:3244012 PMID:8157689 GO_REF:0000033 RGD:2308770 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844 		JBrowse link
G LIPG lipase G, endothelial type involved_in IMP
IBA		 (PMID:19136670) BHF-UCL
GO_Central		 PMID:19136670 GO_REF:0000033 NCBI chr18:49,561,479...49,599,185
Ensembl chr18:49,560,699...49,599,185 		JBrowse link
G LPL lipoprotein lipase involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259 		JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IDA (PMID:18801741) UniProt PMID:18801741 NCBI chr22:31,134,807...31,140,508
Ensembl chr22:31,134,807...31,140,508 		JBrowse link
G PLTP phospholipid transfer protein involved_in IDA
IBA		 (PMID:24369175), (PMID:29883800), (PMID:9132017) AgBase
GO_Central		 PMID:9132017 PMID:24369175 PMID:29883800 GO_REF:0000033 NCBI chr20:45,898,620...45,912,155
Ensembl chr20:45,898,621...45,912,155 		JBrowse link
G SCARB1 scavenger receptor class B member 1 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668 		JBrowse link
intermediate-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LIPC lipase C, hepatic type involved_in TAS (PMID:2839510) BHF-UCL PMID:2839510 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844 		JBrowse link
low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in IEA
ISS		 (PMID:16556852) Ensembl
BHF-UCL		 PMID:16556852 GO_REF:0000107 NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,297,244 		JBrowse link
G AGT angiotensinogen involved_in NAS (PMID:17069818) BHF-UCL PMID:17069818 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR1 angiotensin II receptor type 1 involved_in NAS (PMID:17069818) BHF-UCL PMID:17069818 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G APOA2 apolipoprotein A2 involved_in IDA (PMID:8106353) BHF-UCL PMID:8106353 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631 		JBrowse link
G APOB apolipoprotein B involved_in IMP (PMID:15797858) BHF-UCL PMID:15797858 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G CETP cholesteryl ester transfer protein involved_in IDA
IBA		 (PMID:2833496) BHF-UCL
GO_Central		 PMID:2833496 GO_REF:0000033 NCBI chr16:56,961,950...56,983,845
Ensembl chr16:56,961,923...56,983,845 		JBrowse link
G LIPC lipase C, hepatic type involved_in ISO
IMP		 (PMID:3244012) RGD
BHF-UCL		 PMID:3244012 PMID:8071607 RGD:2308769 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844 		JBrowse link
G MPO myeloperoxidase involved_in IDA (PMID:10772654) BHF-UCL PMID:10772654 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MTTP microsomal triglyceride transfer protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27471003) Ensembl
MGI		 PMID:27471003 GO_REF:0000107 NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997 		JBrowse link
G PLA2G10 phospholipase A2 group X involved_in IDA (PMID:12021277) UniProt PMID:12021277 NCBI chr16:14,672,548...14,701,850
Ensembl chr16:14,672,548...14,694,308 		JBrowse link
G PLA2G10BP phospholipase A2 group XB, pseudogene involved_in IDA (PMID:12021277) UniProt PMID:12021277 NCBI chr16:14,709,058...14,742,495 JBrowse link
G PLA2G12B phospholipase A2 group XIIB acts_upstream_of_or_within ISO (PMID:27471003) MGI PMID:27471003 NCBI chr10:72,934,762...72,954,806
Ensembl chr10:72,934,762...72,954,806 		JBrowse link
G PLA2G2A phospholipase A2 group IIA involved_in TAS (PMID:18827909) BHF-UCL PMID:18827909 NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416 		JBrowse link
G PLA2G2E phospholipase A2 group IIE involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24910243) Ensembl
MGI		 PMID:24910243 GO_REF:0000107 NCBI chr 1:19,920,009...19,923,617
Ensembl chr 1:19,920,009...19,923,617 		JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IDA (PMID:18801741) UniProt PMID:18801741 NCBI chr22:31,134,807...31,140,508
Ensembl chr22:31,134,807...31,140,508 		JBrowse link
G PLA2G5 phospholipase A2 group V involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:24910243) UniProt
MGI		 PMID:24910243 GO_REF:0000024 NCBI chr 1:20,028,408...20,091,911
Ensembl chr 1:20,028,179...20,091,911 		JBrowse link
G PLA2G7 phospholipase A2 group VII involved_in IDA (PMID:8624782) BHF-UCL PMID:8624782 NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693 		JBrowse link
negative regulation of plasma lipoprotein oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 involved_in IDA (PMID:16945374) BHF-UCL PMID:16945374 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304 		JBrowse link
G APOM apolipoprotein M involved_in IEA
IDA		 (PMID:16682745), (PMID:22204862) Ensembl
BHF-UCL		 PMID:16682745 PMID:22204862 GO_REF:0000107 NCBI chr 6:31,652,404...31,658,210
Ensembl chr 6:31,652,416...31,658,210 		JBrowse link
G PON1 paraoxonase 1 NOT|involved_in IDA (PMID:15342686) BHF-UCL PMID:15342686 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532 		JBrowse link
negative regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in IDA (PMID:14967812) BHF-UCL PMID:14967812 NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G APOA2 apolipoprotein A2 involved_in IDA (PMID:14967812) BHF-UCL PMID:14967812 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631 		JBrowse link
G APOC3 apolipoprotein C3 involved_in IC
IDA		 (PMID:18635818)
(PMID:3973011)		 BHF-UCL PMID:3973011 PMID:18635818 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in
acts_upstream_of_or_within		 IEA
IDA		 (PMID:27471003) Ensembl
MGI		 PMID:27471003 GO_REF:0000107 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
plasma lipoprotein particle oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G7 phospholipase A2 group VII involved_in IDA (PMID:8624782) BHF-UCL PMID:8624782 NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693 		JBrowse link
positive regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA5 apolipoprotein A5 involved_in IDA (PMID:18635818) BHF-UCL PMID:18635818 NCBI chr11:116,789,367...116,792,420
Ensembl chr11:116,789,367...116,792,420 		JBrowse link
G APOC2 apolipoprotein C2 involved_in IC (PMID:10727238) BHF-UCL PMID:10727238 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,946,035...44,949,565 		JBrowse link
triglyceride-rich lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 involved_in IDA (PMID:14967812) BHF-UCL PMID:14967812 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631 		JBrowse link
G APOA5 apolipoprotein A5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16166565) Ensembl
MGI		 PMID:16166565 GO_REF:0000107 NCBI chr11:116,789,367...116,792,420
Ensembl chr11:116,789,367...116,792,420 		JBrowse link
G APOC2 apolipoprotein C2 involved_in TAS (PMID:17018885) BHF-UCL PMID:17018885 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,946,035...44,949,565 		JBrowse link
very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 involved_in IDA (PMID:2307668) BHF-UCL PMID:2307668 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304 		JBrowse link
G APOC2 apolipoprotein C2 involved_in TAS (PMID:15778093) BHF-UCL PMID:15778093 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,946,035...44,949,565 		JBrowse link
G APOE apolipoprotein E involved_in IEA
IGI
IDA		 (PMID:12401887)
(PMID:15654758)		 Ensembl
BHF-UCL		 PMID:12401887 PMID:15654758 GO_REF:0000107 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G CETP cholesteryl ester transfer protein involved_in IDA
IBA
IEA		 (PMID:24293641), (PMID:2833496) BHF-UCL
GO_Central
UniProt		 PMID:2833496 PMID:24293641 GO_REF:0000033 GO_REF:0000104 NCBI chr16:56,961,950...56,983,845
Ensembl chr16:56,961,923...56,983,845 		JBrowse link
G LCAT lecithin-cholesterol acyltransferase involved_in IDA (PMID:15654758) BHF-UCL PMID:15654758 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131 		JBrowse link
G LIPC lipase C, hepatic type involved_in ISO
IDA		 (PMID:8640403) RGD
BHF-UCL		 PMID:6791934 PMID:8640403 RGD:2308780 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844 		JBrowse link
G LPL lipoprotein lipase involved_in ISS
IBA
IDA		 (PMID:3973011) BHF-UCL
GO_Central		 PMID:3973011 GO_REF:0000024 GO_REF:0000033 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19787
    multicellular organismal process 8491
      plasma lipoprotein particle organization 55
        plasma lipoprotein particle remodeling 36
          high-density lipoprotein particle remodeling + 17
          low-density lipoprotein particle remodeling 18
          plasma lipoprotein particle oxidation + 4
          triglyceride-rich lipoprotein particle remodeling + 12
Path 2
Term Annotations click to browse term
  biological_process 19787
    cellular process 18956
      cellular component organization or biogenesis 7628
        cellular component organization 7419
          protein-containing complex organization 2150
            protein-containing complex remodeling 39
              protein-lipid complex remodeling 36
                plasma lipoprotein particle remodeling 36
                  high-density lipoprotein particle remodeling + 17
                  low-density lipoprotein particle remodeling 18
                  plasma lipoprotein particle oxidation + 4
                  triglyceride-rich lipoprotein particle remodeling + 12
paths to the root