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ONTOLOGY REPORT - ANNOTATIONS

Term:plasma lipoprotein particle remodeling
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Accession:GO:0034369 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).


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plasma lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC1 apolipoprotein C1 involved_in ISO (PMID:10978346) BHF-UCL PMID:10978346 NCBI chr 1:110,520,177...110,522,563
Ensembl chr 1:110,520,198...110,631,412 		JBrowse link
chylomicron remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LIPC lipase C, hepatic type ISO RGD PMID:7897313 RGD:2308767 NCBI chr30:23,432,460...23,584,037
Ensembl chr30:23,432,493...23,584,037 		JBrowse link
G LPL lipoprotein lipase involved_in ISO (PMID:11342582) UniProt PMID:11342582 NCBI chr25:37,078,306...37,102,729
Ensembl chr25:37,079,756...37,102,700 		JBrowse link
high-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA5 ATP binding cassette subfamily A member 5 involved_in ISO (MGI:4454250|PMID:20382126) BHF-UCL PMID:20382126 MGI:4454250 NCBI chr 9:15,708,070...15,781,100
Ensembl chr 9:15,420,835...15,783,045 		JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852), (MGI:5634884|PMID:21481393) BHF-UCL PMID:16556852 PMID:21481393 MGI:3852307 MGI:5634884 NCBI chr31:36,574,406...36,627,598
Ensembl chr31:36,553,380...36,620,043 		JBrowse link
G APOA1 apolipoprotein A1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 5:16,740,071...16,742,081
Ensembl chr 5:16,740,130...16,741,943 		JBrowse link
G APOA2 apolipoprotein A2 involved_in IBA
IEA		 (PMID:21873635) GO_Central
GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr38:21,263,641...21,265,887
Ensembl chr38:21,262,789...21,265,887 		JBrowse link
G APOA4 apolipoprotein A4 involved_in ISO (PMID:1935934) BHF-UCL PMID:1935934 NCBI chr 5:16,751,588...16,754,215
Ensembl chr 5:16,751,799...16,754,837 		JBrowse link
G APOC3 apolipoprotein C3 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 5:16,744,423...16,746,992
Ensembl chr 5:16,744,423...16,746,992 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440 		JBrowse link
G APOM apolipoprotein M involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr12:1,137,474...1,142,337
Ensembl chr12:1,140,316...1,142,331 		JBrowse link
G LCAT lecithin-cholesterol acyltransferase involved_in ISO (PMID:10722751), (PMID:12167653), (PMID:15210842), (PMID:4335615) UniProt PMID:4335615 PMID:10722751 PMID:12167653 PMID:15210842 NCBI chr 5:81,556,047...81,559,313 JBrowse link
G LIPC lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:8157689 GO_REF:0000107 RGD:2308770 NCBI chr30:23,432,460...23,584,037
Ensembl chr30:23,432,493...23,584,037 		JBrowse link
G LIPG lipase G, endothelial type involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:79,201,514...79,221,090
Ensembl chr 7:79,201,496...79,222,552 		JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr26:24,127,074...24,132,508
Ensembl chr26:24,128,005...24,132,508 		JBrowse link
G PLTP phospholipid transfer protein involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr24:33,189,098...33,199,935
Ensembl chr24:33,189,099...33,199,854 		JBrowse link
G SCARB1 scavenger receptor class B member 1 involved_in ISO (MGI:3056693|PMID:15210842), (MGI:5634884|PMID:21481393) BHF-UCL PMID:15210842 PMID:21481393 MGI:3056693 MGI:5634884 NCBI chr26:5,035,797...5,122,383
Ensembl chr26:5,049,407...5,121,468 		JBrowse link
low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852) BHF-UCL PMID:16556852 MGI:3852307 NCBI chr31:36,574,406...36,627,598
Ensembl chr31:36,553,380...36,620,043 		JBrowse link
G APOA2 apolipoprotein A2 involved_in IBA
IEA		 (PMID:21873635) GO_Central
GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr38:21,263,641...21,265,887
Ensembl chr38:21,262,789...21,265,887 		JBrowse link
G APOB apolipoprotein B involved_in ISO (PMID:15797858) BHF-UCL PMID:15797858 NCBI chr17:15,877,937...15,916,032
Ensembl chr17:15,878,244...15,915,135 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440 		JBrowse link
G LIPC lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:8071607 GO_REF:0000107 RGD:2308769 NCBI chr30:23,432,460...23,584,037
Ensembl chr30:23,432,493...23,584,037 		JBrowse link
G MPO myeloperoxidase involved_in ISO (PMID:10772654) BHF-UCL PMID:10772654 NCBI chr 9:32,927,483...32,938,007
Ensembl chr 9:32,927,483...32,937,820 		JBrowse link
G MTTP microsomal triglyceride transfer protein acts_upstream_of_or_within ISO (MGI:6095248|PMID:27471003) MGI PMID:27471003 MGI:6095248 NCBI chr32:21,582,368...21,626,806
Ensembl chr32:21,570,801...21,628,624 		JBrowse link
G PLA2G10 phospholipase A2 group X involved_in ISO (PMID:12021277) UniProt PMID:12021277 NCBI chr 6:28,573,239...28,591,714
Ensembl chr 6:28,574,387...28,591,703 		JBrowse link
G PLA2G12B phospholipase A2 group XIIB acts_upstream_of_or_within ISO (MGI:6095248|PMID:27471003) MGI PMID:27471003 MGI:6095248 NCBI chr 4:23,539,909...23,561,211
Ensembl chr 4:23,541,258...23,561,041 		JBrowse link
G PLA2G2E phospholipase A2 group IIE acts_upstream_of_or_within ISO (MGI:5605113|PMID:24910243) MGI PMID:24910243 MGI:5605113 NCBI chr 2:78,834,820...78,838,058
Ensembl chr 2:78,831,309...78,841,821 		JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr26:24,127,074...24,132,508
Ensembl chr26:24,128,005...24,132,508 		JBrowse link
G PLA2G5 phospholipase A2 group V acts_upstream_of_or_within
involved_in		 ISO (MGI:5605113|PMID:24910243)
(MGI:6393145|PMID:14962950)		 MGI
UniProt		 PMID:14962950 PMID:24910243 MGI:5605113 MGI:6393145 NCBI chr 2:78,762,851...78,781,642
Ensembl chr 2:78,762,852...78,781,983 		JBrowse link
G PLA2G7 phospholipase A2 group VII involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:14,866,229...14,908,230
Ensembl chr12:14,866,229...14,908,114 		JBrowse link
negative regulation of plasma lipoprotein oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:16,751,588...16,754,215
Ensembl chr 5:16,751,799...16,754,837 		JBrowse link
G APOM apolipoprotein M involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr12:1,137,474...1,142,337
Ensembl chr12:1,140,316...1,142,331 		JBrowse link
G PON1 paraoxonase 1 NOT|involved_in ISO (PMID:15342686) BHF-UCL PMID:15342686 NCBI chr14:20,565,620...20,600,774
Ensembl chr14:20,565,641...20,642,985 		JBrowse link
negative regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 5:16,740,071...16,742,081
Ensembl chr 5:16,740,130...16,741,943 		JBrowse link
G APOA2 apolipoprotein A2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr38:21,263,641...21,265,887
Ensembl chr38:21,262,789...21,265,887 		JBrowse link
G APOC3 apolipoprotein C3 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 5:16,744,423...16,746,992
Ensembl chr 5:16,744,423...16,746,992 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 acts_upstream_of_or_within ISO (MGI:6095248|PMID:27471003)
(PMID:27471003)		 MGI PMID:27471003 MGI:6095248 NCBI chr15:39,497,313...39,608,120
Ensembl chr15:39,536,290...39,608,116 		JBrowse link
plasma lipoprotein particle oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G7 phospholipase A2 group VII involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:14,866,229...14,908,230
Ensembl chr12:14,866,229...14,908,114 		JBrowse link
positive regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA5 apolipoprotein A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:16,774,117...16,777,535
Ensembl chr 5:16,774,501...16,777,768 		JBrowse link
triglyceride-rich lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl
GO_Central		 PMID:21873635 GO_REF:0000107 NCBI chr38:21,263,641...21,265,887
Ensembl chr38:21,262,789...21,265,887 		JBrowse link
G APOA5 apolipoprotein A5 acts_upstream_of_or_within ISO (MGI:3695062|PMID:16166565) MGI PMID:16166565 MGI:3695062 NCBI chr 5:16,774,117...16,777,535
Ensembl chr 5:16,774,501...16,777,768 		JBrowse link
very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:16,740,071...16,742,081
Ensembl chr 5:16,740,130...16,741,943 		JBrowse link
G APOA4 apolipoprotein A4 involved_in IBA
IEA		 (PMID:21873635) GO_Central
GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr 5:16,751,588...16,754,215
Ensembl chr 5:16,751,799...16,754,837 		JBrowse link
G APOA5 apolipoprotein A5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:16,774,117...16,777,535
Ensembl chr 5:16,774,501...16,777,768 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440 		JBrowse link
G LCAT lecithin-cholesterol acyltransferase involved_in ISO (PMID:15654758) BHF-UCL PMID:15654758 NCBI chr 5:81,556,047...81,559,313 JBrowse link
G LIPC lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:6791934 GO_REF:0000107 RGD:2308780 NCBI chr30:23,432,460...23,584,037
Ensembl chr30:23,432,493...23,584,037 		JBrowse link
G LPL lipoprotein lipase involved_in ISO (PMID:3973011) BHF-UCL PMID:3973011 NCBI chr25:37,078,306...37,102,729
Ensembl chr25:37,079,756...37,102,700 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17242
    multicellular organismal process 7879
      plasma lipoprotein particle organization 41
        plasma lipoprotein particle remodeling 27
          high-density lipoprotein particle remodeling + 14
          low-density lipoprotein particle remodeling 13
          plasma lipoprotein particle oxidation + 4
          triglyceride-rich lipoprotein particle remodeling + 10
Path 2
Term Annotations click to browse term
  biological_process 17242
    cellular process 16248
      cellular component organization or biogenesis 6368
        cellular component organization 6173
          protein-containing complex organization 1717
            protein-containing complex remodeling 29
              protein-lipid complex remodeling 27
                plasma lipoprotein particle remodeling 27
                  high-density lipoprotein particle remodeling + 14
                  low-density lipoprotein particle remodeling 13
                  plasma lipoprotein particle oxidation + 4
                  triglyceride-rich lipoprotein particle remodeling + 10
paths to the root