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ONTOLOGY REPORT - ANNOTATIONS


Term:plasma lipoprotein particle remodeling
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Accession:GO:0034369 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).


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plasma lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:10978346) BHF-UCL PMID:10978346 NCBI chrNW_004955555:2,005,962...2,007,239 JBrowse link
chylomicron remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipc lipase C, hepatic type ISO RGD PMID:7897313 RGD:2308767 NCBI chrNW_004955450:15,947,869...16,062,449
Ensembl chrNW_004955450:15,948,187...16,048,766
JBrowse link
G Lpl lipoprotein lipase involved_in ISO (PMID:11342582) UniProt PMID:11342582 NCBI chrNW_004955403:43,646,084...43,672,116
Ensembl chrNW_004955403:43,646,084...43,673,967
JBrowse link
high-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca5 ATP binding cassette subfamily A member 5 involved_in ISO (MGI:4454250|PMID:20382126) BHF-UCL PMID:20382126 MGI:4454250 NCBI chrNW_004955478:3,526,376...3,586,811
Ensembl chrNW_004955478:3,519,368...3,586,811
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852), (MGI:5634884|PMID:21481393) BHF-UCL PMID:16556852 PMID:21481393 MGI:3852307 MGI:5634884 NCBI chrNW_004955407:39,410,262...39,459,383
Ensembl chrNW_004955407:39,410,262...39,459,383
JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO (PMID:21481393)
(PMID:21481393), (PMID:4335615)
BHF-UCL PMID:4335615 PMID:21481393 NCBI chrNW_004955412:18,170,331...18,172,298
Ensembl chrNW_004955412:18,170,331...18,172,298
JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:14967812), (PMID:8106353) BHF-UCL PMID:8106353 PMID:14967812 NCBI chrNW_004955468:12,977,956...12,979,282
Ensembl chrNW_004955468:12,977,956...12,979,753
JBrowse link
G Apoa4 apolipoprotein A4 involved_in ISO (PMID:1935934) BHF-UCL PMID:1935934 NCBI chrNW_004955412:18,158,095...18,160,636
Ensembl chrNW_004955412:18,155,801...18,160,701
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:17438339) BHF-UCL PMID:17438339 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015
JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:12401887) BHF-UCL PMID:12401887 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888
JBrowse link
G Apom apolipoprotein M involved_in ISO (PMID:18006500)
(MGI:3575626|PMID:15793583)
BHF-UCL PMID:15793583 PMID:18006500 MGI:3575626 NCBI chrNW_004955437:190,609...192,781
Ensembl chrNW_004955437:190,609...197,342
JBrowse link
G Lcat lecithin-cholesterol acyltransferase involved_in ISO (PMID:10722751), (PMID:12167653), (PMID:15210842), (PMID:4335615) UniProt PMID:4335615 PMID:10722751 PMID:12167653 PMID:15210842 NCBI chrNW_004955484:8,772,692...8,776,122
Ensembl chrNW_004955484:8,772,692...8,776,122
JBrowse link
G Lipc lipase C, hepatic type involved_in ISO (PMID:3244012) RGD
BHF-UCL
PMID:3244012 PMID:8157689 RGD:2308770 NCBI chrNW_004955450:15,947,869...16,062,449
Ensembl chrNW_004955450:15,948,187...16,048,766
JBrowse link
G Lipg lipase G, endothelial type involved_in ISO (PMID:19136670) BHF-UCL PMID:19136670 NCBI chrNW_004955402:34,666,757...34,689,726
Ensembl chrNW_004955402:34,667,036...34,687,568
JBrowse link
G Pla2g3 phospholipase A2 group III involved_in ISO (PMID:18801741) UniProt PMID:18801741 NCBI chrNW_004955455:5,314,520...5,320,151
Ensembl chrNW_004955455:5,315,450...5,320,053
JBrowse link
G Pltp phospholipid transfer protein involved_in ISO (PMID:24369175), (PMID:29883800), (PMID:9132017) AgBase PMID:9132017 PMID:24369175 PMID:29883800 NCBI chrNW_004955445:11,384,723...11,399,217
Ensembl chrNW_004955445:11,384,723...11,399,217
JBrowse link
G Scarb1 scavenger receptor class B member 1 involved_in ISO (MGI:3056693|PMID:15210842), (MGI:5634884|PMID:21481393) BHF-UCL PMID:15210842 PMID:21481393 MGI:3056693 MGI:5634884 NCBI chrNW_004955482:4,813,502...4,836,479
Ensembl chrNW_004955482:4,813,955...4,837,392
JBrowse link
low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852) BHF-UCL PMID:16556852 MGI:3852307 NCBI chrNW_004955407:39,410,262...39,459,383
Ensembl chrNW_004955407:39,410,262...39,459,383
JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:8106353) BHF-UCL PMID:8106353 NCBI chrNW_004955468:12,977,956...12,979,282
Ensembl chrNW_004955468:12,977,956...12,979,753
JBrowse link
G Apob apolipoprotein B involved_in ISO (PMID:15797858) BHF-UCL PMID:15797858 NCBI chrNW_004955469:3,437,422...3,478,408
Ensembl chrNW_004955469:3,436,450...3,478,424
JBrowse link
G Apoe apolipoprotein E involved_in ISO (MGI:3850619|PMID:15654758) BHF-UCL PMID:15654758 MGI:3850619 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888
JBrowse link
G Lipc lipase C, hepatic type involved_in ISO (PMID:3244012)
PMID:9685400
RGD
BHF-UCL
PMID:3244012 PMID:8071607 PMID:9685400 RGD:2308763 RGD:2308769 NCBI chrNW_004955450:15,947,869...16,062,449
Ensembl chrNW_004955450:15,948,187...16,048,766
JBrowse link
G Mpo myeloperoxidase involved_in ISO (PMID:10772654) BHF-UCL PMID:10772654 NCBI chrNW_004955451:4,743,744...4,753,358
Ensembl chrNW_004955451:4,743,744...4,753,358
JBrowse link
G Mttp microsomal triglyceride transfer protein acts_upstream_of_or_within ISO (MGI:6095248|PMID:27471003) MGI PMID:27471003 MGI:6095248 NCBI chrNW_004955496:7,963,323...8,022,393
Ensembl chrNW_004955496:7,963,262...8,009,838
JBrowse link
G Pla2g10 phospholipase A2 group X involved_in ISO (PMID:12021277) UniProt PMID:12021277 NCBI chrNW_004955442:4,208,497...4,225,893
Ensembl chrNW_004955442:4,208,575...4,225,834
JBrowse link
G Pla2g12b phospholipase A2 group XIIB acts_upstream_of_or_within ISO (MGI:6095248|PMID:27471003) MGI PMID:27471003 MGI:6095248 NCBI chrNW_004955437:18,694,496...18,723,311
Ensembl chrNW_004955437:18,694,496...18,719,337
JBrowse link
G Pla2g2e phospholipase A2 group IIE acts_upstream_of_or_within ISO (MGI:5605113|PMID:24910243) MGI PMID:24910243 MGI:5605113 NCBI chrNW_004955452:522,314...526,095
Ensembl chrNW_004955452:520,361...525,846
JBrowse link
G Pla2g3 phospholipase A2 group III involved_in ISO (PMID:18801741) UniProt PMID:18801741 NCBI chrNW_004955455:5,314,520...5,320,151
Ensembl chrNW_004955455:5,315,450...5,320,053
JBrowse link
G Pla2g5 phospholipase A2 group V acts_upstream_of_or_within
involved_in
ISO (MGI:5605113|PMID:24910243)
(MGI:6393145|PMID:14962950)
MGI
UniProt
PMID:14962950 PMID:24910243 MGI:5605113 MGI:6393145 NCBI chrNW_004955452:662,281...721,507
Ensembl chrNW_004955452:710,271...723,142
JBrowse link
G Pla2g7 phospholipase A2 group VII involved_in ISO (PMID:8624782) BHF-UCL PMID:8624782 NCBI chrNW_004955437:11,534,251...11,577,942
Ensembl chrNW_004955437:11,534,173...11,555,996
JBrowse link
negative regulation of plasma lipoprotein oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A4 involved_in ISO (PMID:16945374) BHF-UCL PMID:16945374 NCBI chrNW_004955412:18,158,095...18,160,636
Ensembl chrNW_004955412:18,155,801...18,160,701
JBrowse link
G Apom apolipoprotein M involved_in ISO (PMID:16682745), (PMID:22204862)
(MGI:5427066|PMID:22204862)
BHF-UCL PMID:16682745 PMID:22204862 MGI:5427066 NCBI chrNW_004955437:190,609...192,781
Ensembl chrNW_004955437:190,609...197,342
JBrowse link
G Pon1 paraoxonase 1 NOT|involved_in ISO (PMID:15342686) BHF-UCL PMID:15342686 NCBI chrNW_004955432:11,893,473...11,923,035
Ensembl chrNW_004955432:11,893,473...11,923,339
JBrowse link
negative regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 involved_in ISO (PMID:14967812) BHF-UCL PMID:14967812 NCBI chrNW_004955412:18,170,331...18,172,298
Ensembl chrNW_004955412:18,170,331...18,172,298
JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:14967812) BHF-UCL PMID:14967812 NCBI chrNW_004955468:12,977,956...12,979,282
Ensembl chrNW_004955468:12,977,956...12,979,753
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:3973011) BHF-UCL PMID:3973011 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015
JBrowse link
G Nr1h4 nuclear receptor subfamily 1 group H member 4 acts_upstream_of_or_within ISO (MGI:6095248|PMID:27471003)
(PMID:27471003)
MGI PMID:27471003 MGI:6095248 NCBI chrNW_004955405:36,160,360...36,236,258
Ensembl chrNW_004955405:36,160,049...36,237,751
JBrowse link
plasma lipoprotein particle oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g7 phospholipase A2 group VII involved_in ISO (PMID:8624782) BHF-UCL PMID:8624782 NCBI chrNW_004955437:11,534,251...11,577,942
Ensembl chrNW_004955437:11,534,173...11,555,996
JBrowse link
positive regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa5 apolipoprotein A5 involved_in ISO (PMID:18635818) BHF-UCL PMID:18635818 NCBI chrNW_004955412:18,128,861...18,131,752
Ensembl chrNW_004955412:18,129,603...18,131,115
JBrowse link
triglyceride-rich lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:14967812) BHF-UCL PMID:14967812 NCBI chrNW_004955468:12,977,956...12,979,282
Ensembl chrNW_004955468:12,977,956...12,979,753
JBrowse link
G Apoa5 apolipoprotein A5 acts_upstream_of_or_within ISO (MGI:3695062|PMID:16166565) MGI PMID:16166565 MGI:3695062 NCBI chrNW_004955412:18,128,861...18,131,752
Ensembl chrNW_004955412:18,129,603...18,131,115
JBrowse link
very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A4 involved_in ISO (PMID:2307668) BHF-UCL PMID:2307668 NCBI chrNW_004955412:18,158,095...18,160,636
Ensembl chrNW_004955412:18,155,801...18,160,701
JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:15654758)
(MGI:3850619|PMID:15654758)
(PMID:12401887)
BHF-UCL PMID:12401887 PMID:15654758 MGI:3850619 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888
JBrowse link
G Lcat lecithin-cholesterol acyltransferase involved_in ISO (PMID:15654758) BHF-UCL PMID:15654758 NCBI chrNW_004955484:8,772,692...8,776,122
Ensembl chrNW_004955484:8,772,692...8,776,122
JBrowse link
G Lipc lipase C, hepatic type involved_in ISO (PMID:8640403) RGD
BHF-UCL
PMID:6791934 PMID:8640403 RGD:2308780 NCBI chrNW_004955450:15,947,869...16,062,449
Ensembl chrNW_004955450:15,948,187...16,048,766
JBrowse link
G Lpl lipoprotein lipase involved_in ISO (PMID:3973011) BHF-UCL PMID:3973011 NCBI chrNW_004955403:43,646,084...43,672,116
Ensembl chrNW_004955403:43,646,084...43,673,967
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12243
    multicellular organismal process 6151
      plasma lipoprotein particle organization 39
        plasma lipoprotein particle remodeling 27
          high-density lipoprotein particle remodeling + 14
          low-density lipoprotein particle remodeling 13
          plasma lipoprotein particle oxidation + 4
          triglyceride-rich lipoprotein particle remodeling + 10
Path 2
Term Annotations click to browse term
  biological_process 12243
    cellular process 11388
      cellular component organization or biogenesis 5024
        cellular component organization 4932
          protein-containing complex organization 1261
            protein-containing complex remodeling 28
              protein-lipid complex remodeling 27
                plasma lipoprotein particle remodeling 27
                  high-density lipoprotein particle remodeling + 14
                  low-density lipoprotein particle remodeling 13
                  plasma lipoprotein particle oxidation + 4
                  triglyceride-rich lipoprotein particle remodeling + 10
paths to the root