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ONTOLOGY REPORT - ANNOTATIONS

Term:plasma lipoprotein particle remodeling
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Accession:GO:0034369 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).
Synonyms:exact_synonym: plasma lipoprotein particle remodelling


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plasma lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC1 apolipoprotein C1 involved_in ISO (PMID:10978346) BHF-UCL PMID:10978346
chylomicron remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LIPC lipase C, hepatic type ISO RGD PMID:7897313 RGD:2308767 NCBI chr15:37,363,507...37,537,723
Ensembl chr15:55,814,017...55,847,005 		JBrowse link
G LPL lipoprotein lipase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:19,164,541...19,193,100
Ensembl chr 8:16,113,415...16,142,966 		JBrowse link
high-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA5 ATP binding cassette subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:63,172,670...63,255,587
Ensembl chr17:68,563,702...68,629,791 		JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852), (MGI:5634884|PMID:21481393)
(PMID:16556852), (PMID:21481393)		 BHF-UCL PMID:16556852 PMID:21481393 MGI:3852307 MGI:5634884 NCBI chr21:28,534,697...28,619,590
Ensembl chr21:41,839,115...41,933,050 		JBrowse link
G APOA1 apolipoprotein A1 involved_in ISO (PMID:21481393), (PMID:4335615) BHF-UCL PMID:4335615 PMID:21481393 NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122 		JBrowse link
G APOA2 apolipoprotein A2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:136,634,754...136,636,122
Ensembl chr 1:140,546,591...140,547,959 		JBrowse link
G APOA4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,659,186...111,661,790
Ensembl chr11:115,591,788...115,594,382 		JBrowse link
G APOC3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G APOM apolipoprotein M involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:31,313,543...31,319,374
Ensembl chr 6:32,206,514...32,209,249 		JBrowse link
G CETP cholesteryl ester transfer protein involved_in IEA UniProt
TreeGrafter
Ensembl		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr16:37,239,756...37,261,859
Ensembl chr16:56,374,363...56,396,103 		JBrowse link
G LCAT lecithin-cholesterol acyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:48,278,137...48,285,305
Ensembl chr16:67,668,646...67,673,127 		JBrowse link
G LIPC lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:8157689 GO_REF:0000107 RGD:2308770 NCBI chr15:37,363,507...37,537,723
Ensembl chr15:55,814,017...55,847,005 		JBrowse link
G LIPG lipase G, endothelial type involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,942,132...42,972,112
Ensembl chr18:46,292,154...46,320,652 		JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:12,158,589...12,164,441
Ensembl chr22:29,995,364...30,001,160 		JBrowse link
G PLTP phospholipid transfer protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:42,237,434...42,251,189
Ensembl chr20:43,324,609...43,337,999 		JBrowse link
G SCARB1 scavenger receptor class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:122,293,803...122,455,314
Ensembl chr12:126,659,532...126,694,767 		JBrowse link
low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852)
(PMID:16556852)		 BHF-UCL PMID:16556852 MGI:3852307 NCBI chr21:28,534,697...28,619,590
Ensembl chr21:41,839,115...41,933,050 		JBrowse link
G APOA2 apolipoprotein A2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:136,634,754...136,636,122
Ensembl chr 1:140,546,591...140,547,959 		JBrowse link
G APOB apolipoprotein B involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:20,986,464...21,029,004
Ensembl chr2A:21,100,356...21,145,129 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G CETP cholesteryl ester transfer protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:37,239,756...37,261,859
Ensembl chr16:56,374,363...56,396,103 		JBrowse link
G LIPC lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:8071607 GO_REF:0000107 RGD:2308769 NCBI chr15:37,363,507...37,537,723
Ensembl chr15:55,814,017...55,847,005 		JBrowse link
G LOC100990946 group 10 secretory phospholipase A2 involved_in ISO (PMID:12021277) UniProt PMID:12021277 NCBI chr16:13,600,152...13,622,629 JBrowse link
G MPO myeloperoxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:52,333,882...52,357,838
Ensembl chr17:57,201,073...57,212,111 		JBrowse link
G MTTP microsomal triglyceride transfer protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27471003) Ensembl
MGI		 PMID:27471003 GO_REF:0000107 NCBI chr 4:91,987,756...92,047,127
Ensembl chr 4:102,648,793...102,708,107 		JBrowse link
G PLA2G12B phospholipase A2 group XIIB acts_upstream_of_or_within ISO (PMID:27471003) MGI PMID:27471003 NCBI chr10:69,482,065...69,502,398
Ensembl chr10:71,946,506...71,965,482 		JBrowse link
G PLA2G2E phospholipase A2 group IIE involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24910243) Ensembl
MGI		 PMID:24910243 GO_REF:0000107 NCBI chr 1:18,874,301...18,878,218
Ensembl chr 1:19,918,391...19,921,639 		JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:12,158,589...12,164,441
Ensembl chr22:29,995,364...30,001,160 		JBrowse link
G PLA2G5 phospholipase A2 group V involved_in
acts_upstream_of_or_within		 ISO (MGI:6393145|PMID:14962950)
(PMID:14962950)
(PMID:24910243)		 UniProt
MGI		 PMID:14962950 PMID:24910243 MGI:6393145 NCBI chr 1:18,983,104...19,046,834
Ensembl chr 1:20,068,110...20,089,840 		JBrowse link
G PLA2G7 phospholipase A2 group VII involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:46,264,262...46,318,487
Ensembl chr 6:47,558,861...47,590,212 		JBrowse link
negative regulation of plasma lipoprotein oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,659,186...111,661,790
Ensembl chr11:115,591,788...115,594,382 		JBrowse link
G APOM apolipoprotein M involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,313,543...31,319,374
Ensembl chr 6:32,206,514...32,209,249 		JBrowse link
G PON1 paraoxonase 1 NOT|involved_in ISO (PMID:15342686) BHF-UCL PMID:15342686 NCBI chr 7:87,253,476...87,279,650
Ensembl chr 7:100,841,286...100,867,493 		JBrowse link
negative regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in ISO (PMID:14967812) BHF-UCL PMID:14967812 NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122 		JBrowse link
G APOA2 apolipoprotein A2 involved_in ISO (PMID:14967812) BHF-UCL PMID:14967812 NCBI chr 1:136,634,754...136,636,122
Ensembl chr 1:140,546,591...140,547,959 		JBrowse link
G APOC3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:27471003) MGI
Ensembl		 PMID:27471003 GO_REF:0000107 NCBI chr12:98,052,778...98,144,085
Ensembl chr12:101,457,885...101,548,058 		JBrowse link
plasma lipoprotein particle oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G7 phospholipase A2 group VII involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:46,264,262...46,318,487
Ensembl chr 6:47,558,861...47,590,212 		JBrowse link
positive regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA5 apolipoprotein A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,625,403...111,627,932
Ensembl chr11:115,559,231...115,562,286 		JBrowse link
triglyceride-rich lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:136,634,754...136,636,122
Ensembl chr 1:140,546,591...140,547,959 		JBrowse link
G APOA5 apolipoprotein A5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16166565) Ensembl
MGI		 PMID:16166565 GO_REF:0000107 NCBI chr11:111,625,403...111,627,932
Ensembl chr11:115,559,231...115,562,286 		JBrowse link
very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:111,659,186...111,661,790
Ensembl chr11:115,591,788...115,594,382 		JBrowse link
G APOA5 apolipoprotein A5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:111,625,403...111,627,932
Ensembl chr11:115,559,231...115,562,286 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G CETP cholesteryl ester transfer protein involved_in IEA UniProt
TreeGrafter
Ensembl		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr16:37,239,756...37,261,859
Ensembl chr16:56,374,363...56,396,103 		JBrowse link
G LCAT lecithin-cholesterol acyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:48,278,137...48,285,305
Ensembl chr16:67,668,646...67,673,127 		JBrowse link
G LIPC lipase C, hepatic type involved_in ISO
IEA		 RGD
Ensembl		 PMID:6791934 GO_REF:0000107 RGD:2308780 NCBI chr15:37,363,507...37,537,723
Ensembl chr15:55,814,017...55,847,005 		JBrowse link
G LPL lipoprotein lipase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:19,164,541...19,193,100
Ensembl chr 8:16,113,415...16,142,966 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16786
    multicellular organismal process 7298
      plasma lipoprotein particle organization 40
        plasma lipoprotein particle remodeling 28
          high-density lipoprotein particle remodeling + 15
          low-density lipoprotein particle remodeling 14
          plasma lipoprotein particle oxidation + 4
          triglyceride-rich lipoprotein particle remodeling + 11
Path 2
Term Annotations click to browse term
  biological_process 16786
    cellular process 16372
      cellular component organization or biogenesis 6710
        cellular component organization 6501
          protein-containing complex organization 1774
            protein-containing complex remodeling 31
              protein-lipid complex remodeling 28
                plasma lipoprotein particle remodeling 28
                  high-density lipoprotein particle remodeling + 15
                  low-density lipoprotein particle remodeling 14
                  plasma lipoprotein particle oxidation + 4
                  triglyceride-rich lipoprotein particle remodeling + 11
paths to the root