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ONTOLOGY REPORT - ANNOTATIONS


Term:plasma lipoprotein particle remodeling
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Accession:GO:0034369 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).



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plasma lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:10978346) RGD PMID:10978346 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
JBrowse link
chylomicron remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipc lipase C, hepatic type IDA RGD PMID:7897313 RGD:2308767 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lpl lipoprotein lipase involved_in ISO
ISS
(PMID:11342582)
GO_REF:0000024
RGD
UniProt
PMID:11342582 GO_REF:0000024 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
high-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca5 ATP binding cassette subfamily A member 5 involved_in IEA
ISO
GO_REF:0000107
(MGI:4454250|PMID:20382126)
Ensembl
RGD
PMID:20382126 GO_REF:0000107 MGI:4454250 NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852), (MGI:5634884|PMID:21481393) RGD PMID:16556852 PMID:21481393 MGI:3852307 MGI:5634884 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO (PMID:21481393) RGD PMID:21481393 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa2 apolipoprotein A2 involved_in IBA
ISO
PMID:21873635
(PMID:14967812), (PMID:8106353)
RGD PMID:8106353 PMID:14967812 PMID:21873635 RGD:13792537 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO
IEA
(PMID:17438339)
GO_REF:0000107
RGD
Ensembl
PMID:17438339 GO_REF:0000107 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Apoe apolipoprotein E involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P08226 (PMID:12401887)
Ensembl
RGD
PMID:12401887 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apom apolipoprotein M involved_in IBA
ISO
PMID:21873635
(MGI:3575626|PMID:15793583)
(PMID:18006500)
RGD PMID:15793583 PMID:18006500 PMID:21873635 MGI:3575626, RGD:13792537 NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550
JBrowse link
G Lcat lecithin cholesterol acyltransferase involved_in ISO (PMID:10722751), (PMID:12167653), (PMID:15210842), (PMID:4335615) RGD PMID:4335615 PMID:10722751 PMID:12167653 PMID:15210842 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lipc lipase C, hepatic type involved_in IDA
IEA
ISO
GO_REF:0000107
(PMID:3244012)
Ensembl
RGD
PMID:3244012 PMID:8157689 GO_REF:0000107, RGD:2308770 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lipg lipase G, endothelial type involved_in ISO (PMID:19136670) RGD PMID:19136670 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
JBrowse link
G Pla2g3 phospholipase A2, group III involved_in ISO (PMID:18801741) RGD PMID:18801741 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913
JBrowse link
G Pltp phospholipid transfer protein involved_in ISO
IBA
(PMID:24369175), (PMID:29883800), (PMID:9132017)
PMID:21873635
RGD PMID:9132017 PMID:24369175 PMID:29883800 PMID:21873635 RGD:13792537 NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647
JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in ISO (MGI:3056693|PMID:15210842), (MGI:5634884|PMID:21481393) RGD PMID:15210842 PMID:21481393 MGI:3056693 MGI:5634884 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3852307|PMID:16556852) RGD PMID:16556852 MGI:3852307 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO
IBA
(PMID:8106353)
PMID:21873635
RGD PMID:8106353 PMID:21873635 RGD:13792537 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apob apolipoprotein B involved_in ISO (PMID:15797858) RGD PMID:15797858 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoe apolipoprotein E involved_in ISO (MGI:3850619|PMID:15654758) RGD PMID:15654758 MGI:3850619 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Lipc lipase C, hepatic type involved_in IDA
IEA
ISO
GO_REF:0000107
(PMID:3244012)
PMID:9685400
Ensembl
RGD
PMID:3244012 PMID:8071607 PMID:9685400 GO_REF:0000107, RGD:2308769, RGD:2308763 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Mpo myeloperoxidase involved_in ISO (PMID:10772654) RGD PMID:10772654 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mttp microsomal triglyceride transfer protein acts_upstream_of_or_within ISO (MGI:6095248|PMID:27471003) RGD PMID:27471003 MGI:6095248 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
JBrowse link
G Pla2g10 phospholipase A2, group X involved_in IEA
ISO
GO_REF:0000107
(PMID:12021277)
Ensembl
RGD
PMID:12021277 GO_REF:0000107 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000
JBrowse link
G Pla2g12b phospholipase A2, group XIIB acts_upstream_of_or_within ISO (MGI:6095248|PMID:27471003) RGD PMID:27471003 MGI:6095248 NCBI chr20:27,369,196...27,389,517
Ensembl chr20:27,370,266...27,388,743
JBrowse link
G Pla2g2e phospholipase A2, group IIE acts_upstream_of_or_within ISO MGI:5660236 (MGI:5605113|PMID:24910243) RGD PMID:24910243 MGI:5605113 NCBI chr 5:151,121,392...151,127,157
Ensembl chr 5:151,121,439...151,126,821
JBrowse link
G Pla2g3 phospholipase A2, group III involved_in ISO (PMID:18801741) RGD PMID:18801741 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913
JBrowse link
G Pla2g5 phospholipase A2, group V involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:6393145|PMID:14962950)
MGI:3042209 (MGI:5605113|PMID:24910243)
UniProt
RGD
PMID:14962950 PMID:24910243 GO_REF:0000024 MGI:5605113 MGI:6393145 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
JBrowse link
G Pla2g7 phospholipase A2 group VII involved_in ISO (PMID:8624782) RGD PMID:8624782 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
JBrowse link
negative regulation of plasma lipoprotein oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A4 involved_in ISO
IEA
(PMID:16945374)
GO_REF:0000107
RGD
Ensembl
PMID:16945374 GO_REF:0000107 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apom apolipoprotein M involved_in ISO (PMID:16682745), (PMID:22204862)
(MGI:5427066|PMID:22204862)
RGD PMID:16682745 PMID:22204862 MGI:5427066 NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550
JBrowse link
G Pon1 paraoxonase 1 NOT|involved_in ISO (PMID:15342686) RGD PMID:15342686 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
negative regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 involved_in ISO (PMID:14967812) RGD PMID:14967812 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:14967812) RGD PMID:14967812 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO
IEA
(PMID:3973011)
GO_REF:0000107
RGD
Ensembl
PMID:3973011 GO_REF:0000107 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6095248|PMID:27471003)
GO_REF:0000107
(PMID:27471003)
RGD
Ensembl
PMID:27471003 GO_REF:0000107 MGI:6095248 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
plasma lipoprotein particle oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g7 phospholipase A2 group VII involved_in ISO (PMID:8624782) RGD PMID:8624782 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
JBrowse link
positive regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa5 apolipoprotein A5 involved_in ISO
IEA
(PMID:18635818)
GO_REF:0000107
RGD
Ensembl
PMID:18635818 GO_REF:0000107 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
triglyceride-rich lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A2 involved_in ISO
IBA
(PMID:14967812)
PMID:21873635
RGD PMID:14967812 PMID:21873635 RGD:13792537 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa5 apolipoprotein A5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3609233 (MGI:3695062|PMID:16166565)
Ensembl
RGD
PMID:16166565 GO_REF:0000107 MGI:3695062 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa4 apolipoprotein A4 involved_in ISO
IEA
IBA
(PMID:2307668)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:2307668 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoa5 apolipoprotein A5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Apoe apolipoprotein E involved_in IEA
ISO
GO_REF:0000107
(MGI:3850619|PMID:15654758)
UniProtKB:P08226 (PMID:12401887), (PMID:15654758)
Ensembl
RGD
PMID:12401887 PMID:15654758 GO_REF:0000107 MGI:3850619 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Lcat lecithin cholesterol acyltransferase involved_in ISO (PMID:15654758) RGD PMID:15654758 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lipc lipase C, hepatic type involved_in IDA
IEA
ISO
GO_REF:0000107
(PMID:8640403)
Ensembl
RGD
PMID:8640403 PMID:6791934 GO_REF:0000107, RGD:2308780 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lpl lipoprotein lipase involved_in ISO (PMID:3973011) RGD PMID:3973011 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19504
    multicellular organismal process 8834
      plasma lipoprotein particle organization 40
        plasma lipoprotein particle remodeling 27
          high-density lipoprotein particle remodeling + 13
          low-density lipoprotein particle remodeling 13
          plasma lipoprotein particle oxidation + 4
          triglyceride-rich lipoprotein particle remodeling + 10
Path 2
Term Annotations click to browse term
  biological_process 19504
    cellular process 18357
      cellular component organization or biogenesis 6519
        cellular component organization 6273
          protein-containing complex subunit organization 1770
            protein-containing complex remodeling 29
              protein-lipid complex remodeling 27
                plasma lipoprotein particle remodeling 27
                  high-density lipoprotein particle remodeling + 13
                  low-density lipoprotein particle remodeling 13
                  plasma lipoprotein particle oxidation + 4
                  triglyceride-rich lipoprotein particle remodeling + 10
paths to the root