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ONTOLOGY REPORT - ANNOTATIONS


Term:'de novo' NAD biosynthetic process from tryptophan
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Accession:GO:0034354 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.



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'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFMID arylformamidase involved_in IEA UniProt
UniProt
GO_REF:0000104 NCBI chr12:3,759,688...3,785,829
Ensembl chr12:3,759,708...3,785,836
JBrowse link
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
GO_Central
PMID:21873635 GO_REF:0000104 NCBI chr 3:97,580,756...97,595,033
Ensembl chr 3:97,580,851...97,595,021
JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr17:9,245,283...9,260,140
Ensembl chr17:9,245,196...9,260,491
JBrowse link
G IDO2 indoleamine 2,3-dioxygenase 2 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr17:9,277,039...9,344,405
Ensembl chr17:9,277,069...9,343,749
JBrowse link
G KMO kynurenine 3-monooxygenase involved_in IEA UniProt
UniProt
GO_REF:0000104 NCBI chr10:12,442,877...12,489,417
Ensembl chr10:12,431,982...12,490,409
JBrowse link
G KYNU kynureninase involved_in IEA UniProt
UniProt
GO_REF:0000104 NCBI chr15:8,847,335...8,982,951
Ensembl chr15:8,850,665...8,982,945
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16975
    metabolic process 10638
      primary metabolic process 9473
        cellular amino acid metabolic process 272
          aromatic amino acid family metabolic process 30
            tryptophan metabolic process 13
              'de novo' NAD biosynthetic process from tryptophan 6
                negative regulation of 'de novo' NAD biosynthetic process from tryptophan 0
                positive regulation of 'de novo' NAD biosynthetic process from tryptophan 0
                regulation of 'de novo' NAD biosynthetic process from tryptophan + 0
Path 2
Term Annotations click to browse term
  biological_process 16975
    metabolic process 10638
      cellular metabolic process 9654
        cellular aromatic compound metabolic process 5252
          nucleobase-containing compound metabolic process 5050
            nucleobase-containing small molecule metabolic process 509
              nucleoside phosphate metabolic process 446
                nucleotide metabolic process 438
                  nucleotide biosynthetic process 227
                    pyridine nucleotide biosynthetic process 19
                      nicotinamide nucleotide biosynthetic process 19
                        NAD biosynthetic process 15
                          'de novo' NAD biosynthetic process 7
                            'de novo' NAD biosynthetic process from tryptophan 6
                              negative regulation of 'de novo' NAD biosynthetic process from tryptophan 0
                              positive regulation of 'de novo' NAD biosynthetic process from tryptophan 0
                              regulation of 'de novo' NAD biosynthetic process from tryptophan + 0
paths to the root