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ONTOLOGY REPORT - ANNOTATIONS

Term:glial cell apoptotic process
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Accession:GO:0034349 term browser browse the term
Definition:Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system.
Synonyms:exact_synonym: apoptosis of glia;   apoptosis of glial cells;   glia apoptosis;   glia programmed cell death by apoptosis;   glial cell programmed cell death by apoptosis;   programmed cell death of glia by apoptosis;   programmed cell death of glial cells by apoptosis;   programmed cell death, glia;   programmed cell death, glial cells
 narrow_synonym: glial cell apoptosis


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glial cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator IEP microglia RGD PMID:18931364 RGD:2313998 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator IEP microglia RGD PMID:18931364 RGD:2313998 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bid BH3 interacting domain death agonist IEP microglia RGD PMID:18931364 RGD:2313998 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Casp3 caspase 3 acts_upstream_of_or_within IEP
IEA
ISO		 microglia
GO_REF:0000107
MGI:2651856 (PMID:11549719)		 Ensembl
RGD		 PMID:11549719 PMID:18931364 GO_REF:0000107, RGD:2313998 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 IEP microglia RGD PMID:18931364 RGD:2313998 Ensembl chr 5:154,109,046...154,126,626 JBrowse link
G Cycs cytochrome c, somatic IEP microglia RGD PMID:18931364 RGD:2313998 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IEP RGD PMID:14997384 RGD:10412686 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Rb1 RB transcriptional corepressor 1 acts_upstream_of_or_within ISO
IEA		 MGI:1857242 (PMID:11549719)
GO_REF:0000107		 RGD
Ensembl		 PMID:11549719 GO_REF:0000107 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
negative regulation of glial cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 involved_in ISO (PMID:12753088) RGD PMID:12753088 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23688253)		 UniProt
RGD		 PMID:23688253 GO_REF:0000024 NCBI chr 1:64,985,161...64,993,274
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Gdnf glial cell derived neurotrophic factor IMP RGD PMID:22251670 RGD:405878066 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Prkca protein kinase C, alpha involved_in ISO
IEA
ISS		 (PMID:9927633)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:9927633 GO_REF:0000024 GO_REF:0000107 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO
IEA
ISS		 (PMID:15774464)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:15774464 GO_REF:0000024 GO_REF:0000107 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkch protein kinase C, eta involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:11772428)		 UniProt
Ensembl
RGD		 PMID:11772428 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:98,027,830...98,226,486
Ensembl chr 6:92,292,000...92,490,654 		JBrowse link
G Prkci protein kinase C, iota involved_in ISO
IEA
ISS		 (PMID:21419810)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:21419810 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:114,250,398...114,310,784
Ensembl chr 2:112,321,929...112,382,352 		JBrowse link
G Rad21 RAD21 cohesin complex component IMP RGD PMID:36538854 RGD:243065265 NCBI chr 7:85,177,715...85,204,657
Ensembl chr 7:83,287,870...83,314,817 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 IMP TNF-induced apoptosis in primary oligodendrocytes RGD PMID:9813034 RGD:2298797 NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:29663649) RGD PMID:29663649 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
negative regulation of oligodendrocyte apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gas6 growth arrest specific 6 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:16723520)		 UniProt
Ensembl
RGD		 PMID:16723520 GO_REF:0000024 GO_REF:0000107 NCBI chr16:82,747,676...82,778,090
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Igf1 insulin-like growth factor 1 IDA RGD PMID:17577243 RGD:12907566 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
oligodendrocyte apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:1857079 (PMID:21935678) RGD PMID:21935678 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000107
(PMID:21725297)
GO_REF:0000033		 UniProt
Ensembl
RGD
GO_Central		 PMID:21725297 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:25,376,400...25,451,323
Ensembl chr 9:17,879,156...17,954,085 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO
IEA
ISS		 (PMID:7720704)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:7720704 GO_REF:0000024 GO_REF:0000107 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
positive regulation of glial cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5 cyclin-dependent kinase 5 IMP RGD PMID:28153522 RGD:13506926 NCBI chr 4:11,647,098...11,651,606
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IMP RGD PMID:14997384 RGD:10412686 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
positive regulation of oligodendrocyte apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap12 A-kinase anchoring protein 12 IMP RGD PMID:20155814 RGD:14348972 NCBI chr 1:43,135,515...43,225,245
Ensembl chr 1:40,730,123...40,819,886 		JBrowse link
G Cers6 ceramide synthase 6 IMP RGD PMID:21148554 RGD:156431059 NCBI chr 3:53,630,637...53,879,692
Ensembl chr 3:53,630,959...53,876,848 		JBrowse link
regulation of glial cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:2447704 (PMID:11673320) RGD PMID:11673320 NCBI chr10:48,294,932...48,324,941
Ensembl chr10:47,795,709...47,825,714 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      cell death 2196
        programmed cell death 2196
          apoptotic process 2119
            glial cell apoptotic process 27
              negative regulation of glial cell apoptotic process + 12
              oligodendrocyte apoptotic process + 7
              positive regulation of glial cell apoptotic process + 4
              regulation of glial cell apoptotic process + 17
paths to the root