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ONTOLOGY REPORT - ANNOTATIONS


Term:adherens junction organization
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Accession:GO:0034332 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
Synonyms:exact_synonym: adherens junction organisation


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adherens junction organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 ADAM metallopeptidase domain 10 involved_in ISO (MGI:6316556|PMID:30639848) RGD PMID:30639848 MGI:6316556 NCBI chr 8:77,107,355...77,237,483
Ensembl chr 8:77,107,536...77,237,483
JBrowse link
G Cdc42 cell division cycle 42 acts_upstream_of_or_within ISO MGI:3619134 (MGI:3664674|PMID:16892058) RGD PMID:16892058 MGI:3664674 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cdh1 cadherin 1 involved_in ISO (PMID:21724833) RGD PMID:21724833 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh10 cadherin 10 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:69,415,174...69,636,849
Ensembl chr 2:69,415,057...69,637,524
JBrowse link
G Cdh11 cadherin 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:2,391,181...2,551,245
Ensembl chr19:2,393,059...2,551,245
JBrowse link
G Cdh12 cadherin 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:71,310,228...72,540,063
Ensembl chr 2:72,006,099...72,540,263
JBrowse link
G Cdh18 cadherin 18 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:73,651,408...74,693,342
Ensembl chr 2:74,360,622...74,693,341
JBrowse link
G Cdh19 cadherin 19 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:32,344,954...32,469,887
Ensembl chr13:32,344,966...32,427,177
JBrowse link
G Cdh20 cadherin 20 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:24,630,298...24,914,463
Ensembl chr13:24,823,488...24,913,884
JBrowse link
G Cdh22 cadherin 22 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:161,574,993...161,971,102
Ensembl chr 3:161,575,631...161,917,285
JBrowse link
G Cdh24 cadherin 24 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:33,277,845...33,287,546
Ensembl chr15:33,278,713...33,285,779
JBrowse link
G Cdh5 cadherin 5 involved_in ISO
IBA
(PMID:26598555)
PMID:21873635
RGD PMID:26598555, PMID:21873635 RGD:13792537 NCBI chr19:1,025,122...1,074,333
Ensembl chr19:1,023,683...1,074,365
JBrowse link
G Cdh6 cadherin 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:63,100,723...63,246,618
Ensembl chr 2:63,101,739...63,166,509
JBrowse link
G Cdh7 cadherin 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:31,081,064...31,228,884
Ensembl chr13:31,081,804...31,231,213
JBrowse link
G Cdh8 cadherin 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:6,031,654...6,431,502
Ensembl chr19:6,046,665...6,426,216
JBrowse link
G Cdh9 cadherin 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:66,938,796...67,078,897
Ensembl chr 2:66,940,057...67,078,784
JBrowse link
G Csk C-terminal Src kinase involved_in IEP
IBA
PMID:21873635 RGD
GO_Central
PMID:15389520, PMID:21873635 RGD:5134367, RGD:13792537 NCBI chr 8:62,405,714...62,424,707
Ensembl chr 8:62,405,715...62,424,303
JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO (MGI:3829282|PMID:19129494) RGD PMID:19129494 MGI:3829282 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Dchs1 dachsous cadherin-related 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:170,594,981...170,629,062
Ensembl chr 1:170,594,822...170,628,915
JBrowse link
G Dsp desmoplakin acts_upstream_of_or_within ISO MGI:1926500|MGI:2156542 (MGI:2154556|PMID:11781569) RGD PMID:11781569 MGI:2154556 NCBI chr17:27,286,811...27,334,453
Ensembl chr17:27,286,796...27,334,379
JBrowse link
G Efnb2 ephrin B2 involved_in ISO (MGI:6316556|PMID:30639848) RGD PMID:30639848 MGI:6316556 NCBI chr16:86,631,151...86,672,050
Ensembl chr16:86,631,064...86,675,049
JBrowse link
G Epha4 Eph receptor A4 involved_in ISO (MGI:6316556|PMID:30639848) RGD PMID:30639848 MGI:6316556 NCBI chr 9:83,111,222...83,253,486
Ensembl chr 9:83,111,222...83,253,458
JBrowse link
G Numb NUMB, endocytic adaptor protein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:894702 (MGI:3721043|PMID:17589506)
Ensembl
RGD
PMID:17589506 GO_REF:0000107 MGI:3721043 NCBI chr 6:107,279,917...107,325,345
Ensembl chr 6:107,279,920...107,325,345
JBrowse link
G Numbl NUMB-like, endocytic adaptor protein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:107423 (MGI:3721043|PMID:17589506)
Ensembl
RGD
PMID:17589506 GO_REF:0000107 MGI:3721043 NCBI chr 1:84,067,841...84,091,659
Ensembl chr 1:84,067,938...84,091,671
JBrowse link
G Plec plectin involved_in ISO
IEA
MGI:3721885 (MGI:5790023|PMID:26519478)
GO_REF:0000107
RGD
Ensembl
PMID:26519478 GO_REF:0000107 MGI:5790023 NCBI chr 7:117,230,319...117,291,859
Ensembl chr 7:117,230,319...117,289,961
JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1-like acts_upstream_of_or_within ISO MGI:4124253 (MGI:6101898|PMID:26787558) RGD PMID:26787558 MGI:6101898 NCBI chr20:14,287,470...14,393,879
Ensembl chr20:14,287,457...14,393,793
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IEP RGD PMID:15389520 RGD:5134367 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
adherens junction assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta involved_in ISO
IEA
(PMID:22855531)
GO_REF:0000107
RGD
Ensembl
PMID:22855531 GO_REF:0000107 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Ctnnb1 catenin beta 1 involved_in ISO
IEA
ISS
(PMID:20086044), (PMID:20123964)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20086044 PMID:20123964 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5494340|PMID:23565059)
Ensembl
RGD
PMID:23565059 GO_REF:0000107 MGI:5494340 NCBI chr 2:206,224,015...206,274,910
Ensembl chr 2:206,224,015...206,274,079
JBrowse link
G Jam3 junctional adhesion molecule 3 involved_in ISO (PMID:19060272) RGD PMID:19060272 NCBI chr 8:28,147,110...28,208,466
Ensembl chr 8:28,147,111...28,208,466
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr11:72,829,407...72,865,815
Ensembl chr11:72,829,238...72,865,902
Ensembl chr11:72,829,238...72,865,902
JBrowse link
G Ramp2 receptor activity modifying protein 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3772552|PMID:18097473)
(PMID:18097473)
UniProt
RGD
PMID:18097473 GO_REF:0000024 MGI:3772552 NCBI chr10:89,166,170...89,168,962
Ensembl chr10:89,166,890...89,168,965
JBrowse link
G Smad7 SMAD family member 7 involved_in ISO
IEA
(PMID:18593713)
GO_REF:0000107
RGD
Ensembl
PMID:18593713 GO_REF:0000107 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Tbcd tubulin folding cofactor D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:110,643,693...110,800,493
Ensembl chr10:110,643,759...110,800,493
JBrowse link
G Vcl vinculin involved_in IEA
ISO
GO_REF:0000107
(PMID:20086044)
Ensembl
RGD
PMID:20086044 GO_REF:0000107 NCBI chr15:3,455,211...3,544,738
Ensembl chr15:3,455,211...3,544,702
JBrowse link
G Zfp703 zinc finger protein 703 involved_in ISO (MGI:4940410|PMID:21317240) RGD PMID:21317240 MGI:4940410 NCBI chr16:69,237,857...69,242,028
Ensembl chr16:69,237,857...69,242,028
JBrowse link
adherens junction maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afdn afadin, adherens junction formation factor acts_upstream_of_or_within ISO (MGI:5605648|PMID:25100583) RGD PMID:25100583 MGI:5605648 NCBI chr 1:53,713,873...53,861,918
Ensembl chr 1:53,715,693...53,802,658
JBrowse link
G Fermt2 FERM domain containing kindlin 2 involved_in ISO (PMID:28799653)
(MGI:6467695|PMID:28799653)
RGD PMID:28799653 MGI:6467695 NCBI chr15:19,807,806...19,876,557
Ensembl chr15:19,807,808...19,876,408
JBrowse link
G Inava innate immunity activator involved_in ISO
IBA
(PMID:29420262)
(MGI:6119883|PMID:29420262)
PMID:21873635
RGD PMID:29420262, PMID:21873635 MGI:6119883, RGD:13792537 NCBI chr13:53,088,438...53,108,713
Ensembl chr13:53,088,439...53,108,713
JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 acts_upstream_of_or_within ISO MGI:5319219 (MGI:5317250|PMID:21406566) RGD PMID:21406566 MGI:5317250 NCBI chr 7:98,820,799...98,960,878
Ensembl chr 7:98,820,812...98,960,837
JBrowse link
G Pkp2 plakophilin 2 IMP RGD PMID:18261826 RGD:6784508 NCBI chr11:88,912,163...88,972,213 JBrowse link
G Tjp1 tight junction protein 1 involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
negative regulation of adherens junction organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:26598555) RGD PMID:26598555 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Rdx radixin involved_in ISO (PMID:22467863) RGD PMID:22467863 NCBI chr 8:56,570,728...56,612,851
Ensembl chr 8:56,585,396...56,610,612
JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:26598555) RGD PMID:26598555 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
positive regulation of adherens junction organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add1 adducin 1 involved_in IBA
ISO
IEA
PMID:21873635
(MGI:5796260|PMID:25978380)
GO_REF:0000107
(PMID:25978380)
RGD
Ensembl
PMID:25978380, PMID:21873635 GO_REF:0000107 MGI:5796260, RGD:13792537 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496
JBrowse link
G Ptpn23 protein tyrosine phosphatase, non-receptor type 23 involved_in IEA
ISO
GO_REF:0000107
(PMID:21724833)
Ensembl
RGD
PMID:21724833 GO_REF:0000107 NCBI chr 8:118,628,777...118,651,238
Ensembl chr 8:118,628,777...118,651,238
JBrowse link
zonula adherens assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 involved_in ISO (PMID:15572692) RGD PMID:15572692 NCBI chr 9:67,234,612...67,284,504
Ensembl chr 9:67,234,303...67,282,600
JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 acts_upstream_of_or_within ISO MGI:3757646 (MGI:3722974|PMID:17765678) RGD PMID:17765678 MGI:3722974 NCBI chr15:120,213...230,312
Ensembl chr15:120,372...228,977
JBrowse link
zonula adherens maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camsap3 calmodulin regulated spectrin-associated protein family, member 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:19041755)
UniProt
RGD
PMID:19041755 GO_REF:0000024 NCBI chr12:2,133,935...2,157,403
Ensembl chr12:2,134,022...2,157,403
JBrowse link
G Kifc3 kinesin family member C3 involved_in ISO (PMID:19041755) RGD PMID:19041755 NCBI chr19:10,305,405...10,339,186
Ensembl chr19:10,320,604...10,339,178
JBrowse link
G Plekha7 pleckstrin homology domain containing A7 involved_in IBA
ISO
PMID:21873635
(PMID:19041755)
RGD PMID:19041755, PMID:21873635 RGD:13792537 NCBI chr 1:185,427,600...185,493,985
Ensembl chr 1:185,356,975...185,538,694
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18343
      cellular component organization or biogenesis 6721
        cellular component organization 6481
          cell junction organization 798
            cell-cell junction organization 229
              adherens junction organization 52
                adherens junction assembly + 12
                adherens junction disassembly 0
                adherens junction maintenance + 9
                negative regulation of adherens junction organization 3
                positive regulation of adherens junction organization 2
                regulation of adherens junction organization + 5
paths to the root