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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of Arp2/3 complex-mediated actin nucleation
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Accession:GO:0034315 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.


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regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP1AR adaptor related protein complex 1 associated regulatory protein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5429457|PMID:22689987) InterPro
MGI
Ensembl
PMID:22689987 GO_REF:0000002 GO_REF:0000107 MGI:5429457 NCBI chr 8:110,386,145...110,420,548
Ensembl chr 8:110,386,776...110,505,320
JBrowse link
G ARF1 ADP ribosylation factor 1 involved_in ISO PMID:23889934 UniProt PMID:23889934 RGD:8553918 NCBI chr 2:51,219,597...51,237,640
Ensembl chr 2:51,219,667...51,237,639
JBrowse link
G ARFIP1 ADP ribosylation factor interacting protein 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:76,168,731...76,270,554
Ensembl chr 8:76,168,388...76,270,787
JBrowse link
G ARFIP2 ADP ribosylation factor interacting protein 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:3,250,011...3,254,916
Ensembl chr 9:3,249,938...3,285,977
JBrowse link
G FAM241A family with sequence similarity 241 member A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:110,468,450...110,504,828
Ensembl chr 8:110,386,776...110,505,320
JBrowse link
G PICK1 protein interacting with PRKCA 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:9,808,444...9,829,677
Ensembl chr 5:9,808,450...9,889,930
JBrowse link
negative regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORO1B coronin 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:5,081,294...5,086,698
Ensembl chr 2:5,080,660...5,086,698
JBrowse link
G CTNNA2 catenin alpha 2 involved_in ISO (PMID:30013181) UniProt PMID:30013181 NCBI chr 3:63,205,073...64,417,990 JBrowse link
G DNAI3 dynein axonemal intermediate chain 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:130,765,580...130,826,828
Ensembl chr 4:130,765,354...130,826,630
JBrowse link
G GMFB glia maturation factor beta involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr 1:183,846,672...183,863,396
Ensembl chr 1:183,846,672...183,863,392
JBrowse link
G GMFG glia maturation factor gamma involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(MGI:5505367|PMID:23727094)
(PMID:21873635)
InterPro
MGI
GO_Central
Ensembl
PMID:21873635 PMID:23727094 GO_REF:0000002 GO_REF:0000107 MGI:5505367 NCBI chr 6:47,990,241...47,997,332
Ensembl chr 6:47,990,237...48,000,590
JBrowse link
G HIP1R huntingtin interacting protein 1 related involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:29,996,388...30,024,343
Ensembl chr14:29,993,655...30,024,216
JBrowse link
G PICK1 protein interacting with PRKCA 1 involved_in ISO PMID:18297063 UniProt PMID:18297063 RGD:8554748 NCBI chr 5:9,808,444...9,829,677
Ensembl chr 5:9,808,450...9,889,930
JBrowse link
positive regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI2 abl interactor 2 involved_in ISO (PMID:21107423) UniProt PMID:21107423 NCBI chr15:106,776,627...106,903,889
Ensembl chr15:106,776,625...106,900,334
JBrowse link
G BRK1 BRICK1 subunit of SCAR/WAVE actin nucleating complex involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:66,315,438...66,324,641
Ensembl chr13:66,315,433...66,324,174
JBrowse link
G CYFIP1 cytoplasmic FMR1 interacting protein 1 involved_in ISO (PMID:21107423) UniProt PMID:21107423 NCBI chr15:32,064,431...32,175,095 JBrowse link
G FCHSD2 FCH and double SH3 domains 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:7,366,516...7,619,960
Ensembl chr 9:7,366,521...7,619,926
JBrowse link
G LOC110256054 wiskott-Aldrich syndrome protein family member 1-like involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:41,049,943...41,076,524 JBrowse link
G NCKAP1 NCK associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:88,425,861...88,528,417
Ensembl chr15:88,425,141...88,528,231
JBrowse link
G WAS WASP actin nucleation promoting factor involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:42,774,597...42,793,055
Ensembl chr  X:42,774,588...42,793,055
JBrowse link
G WASF1 WASP family member 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:76,107,595...76,180,335 JBrowse link
G WASF2 WASP family member 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:84,621,742...84,697,428
Ensembl chr 6:84,622,775...84,697,429
JBrowse link
G WASF3 WASP family member 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:4,261,121...4,366,258
Ensembl chr11:4,261,177...4,366,254
JBrowse link
G WASL WASP like actin nucleation promoting factor involved_in IEA InterPro GO_REF:0000002 NCBI chr18:23,722,188...23,789,516
Ensembl chr18:23,722,188...23,789,506
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16574
    cellular process 15856
      actin filament-based process 802
        actin cytoskeleton organization 714
          actin filament organization 447
            actin nucleation 53
              Arp2/3 complex-mediated actin nucleation 38
                regulation of Arp2/3 complex-mediated actin nucleation 23
                  negative regulation of Arp2/3 complex-mediated actin nucleation 7
                  positive regulation of Arp2/3 complex-mediated actin nucleation 11
Path 2
Term Annotations click to browse term
  biological_process 16574
    cellular process 15856
      cellular component organization or biogenesis 6092
        cellular component organization 5924
          organelle organization 3744
            cytoskeleton organization 1381
              actin cytoskeleton organization 714
                actin filament organization 447
                  actin polymerization or depolymerization 218
                    regulation of actin polymerization or depolymerization 190
                      regulation of actin filament polymerization 172
                        positive regulation of actin filament polymerization 102
                          actin nucleation 53
                            Arp2/3 complex-mediated actin nucleation 38
                              regulation of Arp2/3 complex-mediated actin nucleation 23
                                negative regulation of Arp2/3 complex-mediated actin nucleation 7
                                positive regulation of Arp2/3 complex-mediated actin nucleation 11
paths to the root