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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of Arp2/3 complex-mediated actin nucleation
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Accession:GO:0034315 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.


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regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1ar adaptor related protein complex 1 associated regulatory protein acts_upstream_of_or_within ISO (MGI:5429457|PMID:22689987) MGI PMID:22689987 MGI:5429457 NCBI chrNW_004955457:14,456,414...14,471,584
Ensembl chrNW_004955457:14,457,990...14,491,435
JBrowse link
G Arf1 ADP ribosylation factor 1 involved_in ISO PMID:23889934 UniProt PMID:23889934 RGD:8553918 NCBI chrNW_004955581:319,942...335,112
Ensembl chrNW_004955581:319,942...335,112
JBrowse link
negative regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1b coronin 1B involved_in ISO (PMID:17350576), (PMID:18775315) UniProt PMID:17350576 PMID:18775315 NCBI chrNW_004955422:18,035,629...18,041,009
Ensembl chrNW_004955422:18,034,873...18,041,483
JBrowse link
G Ctnna2 catenin alpha 2 involved_in ISO (PMID:30013181) UniProt PMID:30013181 NCBI chrNW_004955424:5,985,170...7,055,830
Ensembl chrNW_004955424:5,986,073...6,911,826
JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 involved_in ISO (PMID:32128961) UniProt PMID:32128961 NCBI chrNW_004955423:8,870,877...8,928,070
Ensembl chrNW_004955423:8,870,602...8,928,743
JBrowse link
G Gmfg glia maturation factor gamma acts_upstream_of_or_within ISO (MGI:5505367|PMID:23727094) MGI PMID:23727094 MGI:5505367 NCBI chrNW_004955468:213,010...222,464
Ensembl chrNW_004955468:213,010...222,464
JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO (MGI:5805366|PMID:17318189) ParkinsonsUK-UCL PMID:17318189 MGI:5805366 NCBI chrNW_004955482:5,885,807...5,896,386
Ensembl chrNW_004955482:5,884,839...5,896,389
JBrowse link
G Pick1 protein interacting with PRKCA 1 involved_in ISO PMID:18297063 UniProt PMID:18297063 RGD:8554748 NCBI chrNW_004955413:24,383,130...24,399,092
Ensembl chrNW_004955413:24,383,130...24,399,196
JBrowse link
positive regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl interactor 2 involved_in ISO (PMID:21107423) UniProt PMID:21107423 NCBI chrNW_004955457:11,451,851...11,562,692
Ensembl chrNW_004955457:11,451,851...11,562,696
JBrowse link
G Brk1 BRICK1 subunit of SCAR/WAVE actin nucleating complex involved_in ISO (PMID:21107423) UniProt PMID:21107423 NCBI chrNW_004955561:1,545,921...1,554,423
Ensembl chrNW_004955561:1,545,576...1,554,618
JBrowse link
G Fchsd2 FCH and double SH3 domains 2 involved_in ISO (PMID:29887380) UniProt PMID:29887380 NCBI chrNW_004955414:18,343,832...18,597,675
Ensembl chrNW_004955414:18,343,832...18,597,675
JBrowse link
G Nckap1 NCK associated protein 1 involved_in ISO (PMID:21107423) UniProt PMID:21107423 NCBI chrNW_004955403:14,476,689...14,554,380
Ensembl chrNW_004955403:14,480,162...14,554,702
JBrowse link
G Wasf1 WASP family member 1 involved_in ISO (PMID:21107423) UniProt PMID:21107423 NCBI chrNW_004955411:34,893,287...34,966,670
Ensembl chrNW_004955411:34,889,566...34,965,769
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11974
    cellular process 11208
      actin filament-based process 623
        actin cytoskeleton organization 540
          actin filament organization 328
            actin nucleation 34
              Arp2/3 complex-mediated actin nucleation 24
                regulation of Arp2/3 complex-mediated actin nucleation 13
                  negative regulation of Arp2/3 complex-mediated actin nucleation 6
                  positive regulation of Arp2/3 complex-mediated actin nucleation 5
Path 2
Term Annotations click to browse term
  biological_process 11974
    cellular process 11208
      cellular component organization or biogenesis 4965
        cellular component organization 4882
          organelle organization 3021
            cytoskeleton organization 1078
              actin cytoskeleton organization 540
                actin filament organization 328
                  actin polymerization or depolymerization 158
                    regulation of actin polymerization or depolymerization 133
                      regulation of actin filament polymerization 114
                        positive regulation of actin filament polymerization 74
                          actin nucleation 34
                            Arp2/3 complex-mediated actin nucleation 24
                              regulation of Arp2/3 complex-mediated actin nucleation 13
                                negative regulation of Arp2/3 complex-mediated actin nucleation 6
                                positive regulation of Arp2/3 complex-mediated actin nucleation 5
paths to the root