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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of transcription elongation by RNA polymerase II
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Accession:GO:0034243 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
Synonyms:exact_synonym: regulation of RNA elongation from RNA polymerase II promoter;   regulation of transcription elongation from RNA polymerase II promoter
 related_synonym: regulation of gene-specific transcription elongation from RNA polymerase II promoter
 alt_id: GO:0090039



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regulation of transcription elongation by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eaf1 ELL associated factor 1 involved_in ISO
IEA
(PMID:32087315)
GO_REF:0000107
RGD
Ensembl
PMID:32087315 GO_REF:0000107 NCBI chr16:6,698,322...6,713,071
Ensembl chr16:6,698,322...6,713,071
JBrowse link
G Eaf2 ELL associated factor 2 involved_in ISO (PMID:32087315) RGD PMID:32087315 NCBI chr11:63,960,200...64,004,610
Ensembl chr11:63,960,200...64,004,610
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor IMP RGD PMID:31644904 RGD:126925983 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit involved_in ISO (PMID:9450929) RGD PMID:9450929 NCBI chr10:72,539,323...72,545,582
Ensembl chr10:72,539,382...72,545,831
JBrowse link
G Supt5h SPT5 homolog, DSIF elongation factor subunit involved_in ISO
IEA
(PMID:9450929)
GO_REF:0000107
RGD
Ensembl
PMID:9450929 GO_REF:0000107 NCBI chr 1:83,586,713...83,616,971
Ensembl chr 1:83,586,718...83,616,892
JBrowse link
G Tox4 TOX high mobility group box family member 4 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr15:24,989,246...25,002,833
Ensembl chr15:24,988,853...25,002,833
JBrowse link
G Wdr43 WD repeat domain 43 involved_in ISO
IEA
(PMID:31128943)
GO_REF:0000107
RGD
Ensembl
PMID:31128943 GO_REF:0000107 NCBI chr 6:23,845,499...23,884,846
Ensembl chr 6:23,845,499...23,884,846
JBrowse link
G Zmynd11 zinc finger, MYND-type containing 11 involved_in IBA
IEA
ISO
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002
(PMID:24590075)
GO_Central
Ensembl
InterPro
RGD
PMID:24590075 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr17:60,542,669...60,631,913
Ensembl chr17:60,543,077...60,631,902
JBrowse link
negative regulation of transcription elongation by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin1 axin 1 acts_upstream_of_or_within ISO
IEA
(PMID:10318824), (PMID:19204372)
GO_REF:0000107
RGD
Ensembl
PMID:10318824 PMID:19204372 GO_REF:0000107 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615
JBrowse link
G Eapp E2F-associated phosphoprotein acts_upstream_of_or_within ISO
IEA
(PMID:15716352)
GO_REF:0000107
RGD
Ensembl
PMID:15716352 GO_REF:0000107 NCBI chr 6:72,166,486...72,194,357
Ensembl chr 6:72,170,301...72,193,734
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO
IEA
MGI:2661097 (PMID:19303854)
GO_REF:0000107
RGD
Ensembl
PMID:19303854 GO_REF:0000107 NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 involved_in ISO
ISS
(PMID:14580347)
GO_REF:0000024
RGD
UniProt
PMID:14580347 GO_REF:0000024 NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in IEA
ISO
GO_REF:0000107
(PMID:10490622)
Ensembl
RGD
PMID:10490622 GO_REF:0000107 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
JBrowse link
G Nelfa negative elongation factor complex member A involved_in
acts_upstream_of_or_within
ISO
IBA
IEA
(PMID:12612062)
GO_REF:0000033
(PMID:21670248)
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:12612062 PMID:21670248 GO_REF:0000033 GO_REF:0000107 NCBI chr14:76,808,920...76,832,998
Ensembl chr14:76,808,870...76,832,994
JBrowse link
G Nelfb negative elongation factor complex member B involved_in ISO
IBA
IEA
(PMID:12612062)
GO_REF:0000033
(PMID:19340312), (PMID:24656816), (PMID:25773599)
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:12612062 PMID:19340312 PMID:24656816 PMID:25773599 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:8,010,883...8,027,403
Ensembl chr 3:8,010,888...8,027,403
JBrowse link
G Nelfcd negative elongation factor complex member C/D involved_in ISO
IBA
IEA
(PMID:12612062)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:12612062 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:163,213,765...163,224,886
Ensembl chr 3:163,213,762...163,224,884
JBrowse link
G Nelfe negative elongation factor complex member E involved_in
acts_upstream_of_or_within
ISO
IBA
IEA
(PMID:12612062), (PMID:14701750), (PMID:27256882)
GO_REF:0000033
(PMID:31399344)
(PMID:21670248)
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:12612062 PMID:14701750 PMID:21670248 PMID:27256882 PMID:31399344 GO_REF:0000033 GO_REF:0000107 NCBI chr20:3,976,512...3,982,389
Ensembl chr20:3,976,518...3,982,355
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO
IEA
(PMID:35393539)
GO_REF:0000107
RGD
Ensembl
PMID:35393539 GO_REF:0000107 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:31677974)
Ensembl
UniProt
RGD
PMID:31677974 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:31677974)
UniProt
Ensembl
RGD
PMID:31677974 GO_REF:0000024 GO_REF:0000107 NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611
JBrowse link
G Recql5 RecQ like helicase 5 involved_in ISO
ISS
(PMID:23748380)
GO_REF:0000024
RGD
UniProt
PMID:23748380 GO_REF:0000024 NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652
JBrowse link
G Rnf168 ring finger protein 168 involved_in ISS
ISO
GO_REF:0000024
(PMID:20550933)
UniProt
RGD
PMID:20550933 GO_REF:0000024 NCBI chr11:81,991,352...82,013,306
Ensembl chr11:68,486,321...68,508,277
JBrowse link
G Rnf8 ring finger protein 8 involved_in ISO
ISS
(PMID:20550933)
GO_REF:0000024
RGD
UniProt
PMID:20550933 GO_REF:0000024 NCBI chr20:7,683,890...7,708,437
Ensembl chr20:7,682,322...7,708,491
JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO
IEA
(PMID:17284610)
GO_REF:0000107
RGD
Ensembl
PMID:17284610 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Sirt6 sirtuin 6 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:25247314), (PMID:31399344)
GO_REF:0000107
(PMID:31399344)
RGD
Ensembl
PMID:25247314 PMID:31399344 GO_REF:0000107 NCBI chr 7:8,733,056...8,738,543
Ensembl chr 7:8,082,364...8,098,914
JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit acts_upstream_of_or_within ISO (PMID:21670248) RGD PMID:21670248 NCBI chr10:72,539,323...72,545,582
Ensembl chr10:72,539,382...72,545,831
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor involved_in ISO (PMID:7660122) RGD PMID:7660122 NCBI chr 4:148,328,099...148,334,992
Ensembl chr 4:146,772,468...146,779,377
JBrowse link
positive regulation of transcription elongation by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd4 bromodomain containing 4 acts_upstream_of_or_within
involved_in
ISO (PMID:18039861)
(PMID:19103749)
RGD PMID:18039861 PMID:19103749 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
JBrowse link
G Btbd18 BTB domain containing 18 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:69,743,057...69,751,096
Ensembl chr 3:69,745,012...69,751,042
JBrowse link
G Cbx7 chromobox 7 IMP RGD PMID:19706751 RGD:9586729 NCBI chr 7:113,341,030...113,358,716
Ensembl chr 7:111,460,656...111,477,973
JBrowse link
G Ccnk cyclin K involved_in ISO
IEA
(PMID:22988298), (PMID:26748711)
GO_REF:0000107
RGD
Ensembl
PMID:22988298 PMID:26748711 GO_REF:0000107 NCBI chr 6:127,090,115...127,113,195
Ensembl chr 6:127,090,569...127,113,191
JBrowse link
G Ccnt1 cyclin T1 involved_in ISO
IEA
(PMID:30134174), (PMID:35393539), (PMID:9499409)
GO_REF:0000107
RGD
Ensembl
PMID:9499409 PMID:30134174 PMID:35393539 GO_REF:0000107 NCBI chr 7:129,687,146...129,718,080
Ensembl chr 7:129,691,209...129,717,871
JBrowse link
G Ccnt2 cyclin T2 involved_in ISO (PMID:9499409) RGD PMID:9499409 NCBI chr13:39,251,573...39,293,172
Ensembl chr13:39,251,573...39,292,019
JBrowse link
G Cdc73 cell division cycle 73 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656
JBrowse link
G Cdk12 cyclin-dependent kinase 12 involved_in ISO
IBA
IEA
(PMID:22988298)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:22988298 GO_REF:0000033 GO_REF:0000107 NCBI chr10:83,201,177...83,256,906
Ensembl chr10:83,201,211...83,280,888
Ensembl chr10:83,201,211...83,280,888
JBrowse link
G Cdk13 cyclin-dependent kinase 13 involved_in ISO
IEA
IBA
(PMID:26748711)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:26748711 GO_REF:0000033 GO_REF:0000107 NCBI chr17:47,251,145...47,344,675
Ensembl chr17:47,251,163...47,341,721
JBrowse link
G Cdk9 cyclin-dependent kinase 9 involved_in ISS
IBA
ISO
IEA
GO_REF:0000024
GO_REF:0000033
(PMID:14701750), (PMID:30134174), (PMID:9499409)
GO_REF:0000107
UniProt
GO_Central
RGD
Ensembl
PMID:9499409 PMID:14701750 PMID:30134174 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
JBrowse link
G Ctnnb1 catenin beta 1 involved_in IEA
ISO
GO_REF:0000107
MGI:2148567|MGI:3841145 (PMID:30478225)
Ensembl
RGD
PMID:30478225 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Dab2 DAB adaptor protein 2 involved_in ISO (PMID:15894542) RGD PMID:15894542 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Eapp E2F-associated phosphoprotein acts_upstream_of_or_within ISO
IEA
(PMID:15716352)
GO_REF:0000107
RGD
Ensembl
PMID:15716352 GO_REF:0000107 NCBI chr 6:72,166,486...72,194,357
Ensembl chr 6:72,170,301...72,193,734
JBrowse link
G Ell elongation factor for RNA polymerase II involved_in ISO
IEA
IBA
(PMID:23932780)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:23932780 GO_REF:0000033 GO_REF:0000107 NCBI chr16:18,843,775...18,891,484
Ensembl chr16:18,843,780...18,891,118
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781
JBrowse link
G Ell2l1 elongation factor for RNA polymerase II 2 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:145,878,600...145,888,249
Ensembl chr  X:145,878,614...145,887,896
JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:108,413,035...108,417,181
Ensembl chr 3:108,410,448...108,417,132
JBrowse link
G Eloc elongin C IDA RGD PMID:8202474 RGD:730008 NCBI chr 5:7,444,769...7,461,187
Ensembl chr 5:2,661,724...2,677,890
Ensembl chr20:2,661,724...2,677,890
JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:1,844,027...1,853,455
Ensembl chr 9:1,843,901...1,853,423
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO MGI:2158690 (PMID:21245044) RGD PMID:21245044 NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416
JBrowse link
G Ldb1 LIM domain binding 1 involved_in ISO
IEA
(PMID:20570862)
GO_REF:0000107
RGD
Ensembl
PMID:20570862 GO_REF:0000107 NCBI chr 1:244,864,168...244,890,007
Ensembl chr 1:244,877,173...244,890,013
JBrowse link
G Leo1 LEO1 homolog, Paf1/RNA polymerase II complex component involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:76,199,547...76,223,983
Ensembl chr 8:76,199,099...76,223,983
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 IMP RGD PMID:18086894 RGD:2292639 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:39603239), (PMID:39603240)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:39603239 PMID:39603240 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:39603239), (PMID:39603240)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:39603239 PMID:39603240 GO_REF:0000024 GO_REF:0000107 NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611
JBrowse link
G Pwwp2a PWWP domain containing 2A involved_in ISO
IEA
(PMID:30228260)
GO_REF:0000107
RGD
Ensembl
PMID:30228260 GO_REF:0000107 NCBI chr10:28,155,509...28,195,255
Ensembl chr10:28,155,605...28,194,308
JBrowse link
G Pwwp2b PWWP domain containing 2B involved_in ISO
IEA
(PMID:30228260)
GO_REF:0000107
RGD
Ensembl
PMID:30228260 GO_REF:0000107 NCBI chr 1:194,040,395...194,059,979
Ensembl chr 1:194,041,341...194,059,958
JBrowse link
G Supt5h SPT5 homolog, DSIF elongation factor subunit involved_in IEA
ISO
GO_REF:0000107
(PMID:16427012)
Ensembl
RGD
PMID:16427012 GO_REF:0000107 NCBI chr 1:83,586,713...83,616,971
Ensembl chr 1:83,586,718...83,616,892
JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor involved_in ISO (PMID:17234882) RGD PMID:17234882 NCBI chr10:63,103,920...63,140,780
Ensembl chr10:63,103,921...63,140,780
JBrowse link
G Tox4 TOX high mobility group box family member 4 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:39603239), (PMID:39603240)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:39603239 PMID:39603240 GO_REF:0000024 GO_REF:0000107 NCBI chr15:24,989,246...25,002,833
Ensembl chr15:24,988,853...25,002,833
JBrowse link
G Wdr82 WD repeat domain 82 involved_in IEA
ISO
GO_REF:0000107
(PMID:39603239), (PMID:39603240)
Ensembl
RGD
PMID:39603239 PMID:39603240 GO_REF:0000107 NCBI chr 8:106,814,569...106,834,535
Ensembl chr 8:106,814,569...106,834,438
JBrowse link
G Zmynd8 zinc finger, MYND-type containing 8 involved_in ISO
IEA
UniProtKB:P50750 (PMID:26655721), (PMID:30134174)
GO_REF:0000107
RGD
Ensembl
PMID:26655721 PMID:30134174 GO_REF:0000107 NCBI chr 3:154,528,917...154,629,532
Ensembl chr 3:154,529,043...154,628,463
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        biosynthetic process 8630
          macromolecule biosynthetic process 7628
            gene expression 7191
              DNA-templated transcription 3579
                DNA-templated transcription elongation 124
                  transcription elongation by RNA polymerase II 110
                    regulation of transcription elongation by RNA polymerase II 53
                      negative regulation of transcription elongation by RNA polymerase II 19
                      positive regulation of transcription elongation by RNA polymerase II 32
Path 2
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        primary metabolic process 10727
          nucleobase-containing compound metabolic process 5900
            nucleic acid metabolic process 5283
              RNA metabolic process 4695
                RNA biosynthetic process 4407
                  DNA-templated transcription 3579
                    DNA-templated transcription elongation 124
                      regulation of DNA-templated transcription elongation 59
                        regulation of transcription elongation by RNA polymerase II 53
                          negative regulation of transcription elongation by RNA polymerase II 19
                          positive regulation of transcription elongation by RNA polymerase II 32
paths to the root