Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to amino acid starvation
go back to main search page
Accession:GO:0034198 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.
Synonyms:narrow_synonym: GAAC response;   general amino acid control response


show annotations for term's descendants           Sort by:
 
cellular response to amino acid starvation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF3 activating transcription factor 3 IEA Ensembl GO_REF:0000107 NCBI chr 7:10,784,445...10,795,285
Ensembl chr 7:10,782,064...10,794,163
JBrowse link
G ATF4 activating transcription factor 4 IEA Ensembl GO_REF:0000107 NCBI chr10:25,528,880...25,531,018
Ensembl chr10:25,528,874...25,530,993
JBrowse link
G BECN1 beclin 1 ISO RGD PMID:22835012 RGD:11561942 NCBI chr 9:20,204,203...20,215,081
Ensembl chr 9:20,204,220...20,214,236
JBrowse link
G BMT2 base methyltransferase of 25S rRNA 2 homolog IEA Ensembl GO_REF:0000107 NCBI chr14:52,363,629...52,456,440
Ensembl chr14:52,366,219...52,456,404
JBrowse link
G C10H12orf66 chromosome 10 C12orf66 homolog IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:6,977,602...6,998,204
Ensembl chr10:6,979,624...6,998,138
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO (PMID:26102367)
(MGI:MGI:5700278|PMID:26102367)
UniProtKB PMID:26102367 MGI:MGI:5700278 NCBI chr12:5,746,898...5,755,103
Ensembl chr12:5,745,852...5,892,281
JBrowse link
G DAP death associated protein ISO (PMID:20537536) UniProtKB PMID:20537536 NCBI chr34:3,616,960...3,682,424 JBrowse link
G DAPL1 death associated protein like 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr36:4,678,544...4,698,711
Ensembl chr36:4,678,563...4,698,710
JBrowse link
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr26:24,629,369...24,754,728
Ensembl chr26:24,630,295...24,754,256
JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr17:29,494,641...29,537,933
Ensembl chr17:29,496,128...29,537,933
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 IEA Ensembl GO_REF:0000107 NCBI chr17:37,886,397...37,950,671
Ensembl chr17:37,886,601...37,949,812
JBrowse link
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 ISO (MGI:MGI:3722921|PMID:14729979)
(MGI:MGI:5576818|PMID:24333428)
(PMID:25329545)
ParkinsonsUK-UCL
UniProtKB
PMID:14729979, PMID:24333428, PMID:25329545 MGI:MGI:3722921, MGI:MGI:5576818 NCBI chr30:7,144,727...7,248,014
Ensembl chr30:7,144,570...7,248,000
JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha IEA Ensembl GO_REF:0000107 NCBI chr 8:41,354,400...41,371,676
Ensembl chr 8:41,351,244...41,371,056
JBrowse link
G FAS Fas cell surface death receptor ISO (PMID:11096076) CAFA PMID:11096076 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321
JBrowse link
G FLCN folliculin IEA Ensembl GO_REF:0000107 NCBI chr 5:42,176,093...42,195,718
Ensembl chr 5:42,176,291...42,195,711
JBrowse link
G GCN1 GCN1 activator of EIF2AK4 ISO (MGI:MGI:5576818|PMID:24333428) UniProtKB PMID:24333428 MGI:MGI:5576818 NCBI chr26:16,087,380...16,146,865
Ensembl chr26:16,087,382...16,146,813
JBrowse link
G HNRNPL heterogeneous nuclear ribonucleoprotein L ISO RGD PMID:19273590 RGD:9999430 NCBI chr 1:114,267,195...114,279,107
Ensembl chr 1:114,267,210...114,278,837
JBrowse link
G IMPACT impact RWD domain protein ISO (MGI:MGI:5576818|PMID:24333428) UniProtKB PMID:24333428 MGI:MGI:5576818 NCBI chr 7:63,947,117...63,976,628
Ensembl chr 7:63,948,157...63,976,613
JBrowse link
G ITFG2 integrin alpha FG-GAP repeat containing 2 IEA Ensembl GO_REF:0000107 NCBI chr27:41,933,741...41,944,464
Ensembl chr27:41,934,575...41,944,472
JBrowse link
G KPTN kaptin, actin binding protein IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:108,535,140...108,544,405
Ensembl chr 1:108,535,681...108,543,164
JBrowse link
G LARS1 leucyl-tRNA synthetase 1 ISO (PMID:22424946) CAFA PMID:22424946 NCBI chr 2:40,544,031...40,619,268
Ensembl chr 2:40,544,210...40,635,281
JBrowse link
G LOC106559613 60S ribosomal protein L17 pseudogene ISO RGD PMID:8144559 RGD:1304507 NCBI chr13:12,340,847...12,341,465 JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:22835012 RGD:11561942 NCBI chr24:23,672,343...23,673,937
Ensembl chr24:23,633,579...23,673,921
JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 IEA Ensembl GO_REF:0000107 NCBI chr 1:29,107,813...29,306,437
Ensembl chr 1:29,108,591...29,306,503
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO (PMID:11096076) CAFA PMID:11096076 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 IEA Ensembl GO_REF:0000107 NCBI chr28:323,361...410,367
Ensembl chr28:368,513...406,401
JBrowse link
G MIOS meiosis regulator for oocyte development IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:23,171,028...23,208,055
Ensembl chr14:23,171,050...23,555,257
JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO (PMID:22343943), (PMID:22424946), (PMID:22576015), (PMID:22692423) UniProt PMID:22343943, PMID:22424946, PMID:22576015, PMID:22692423 NCBI chr 2:84,818,893...84,939,283
Ensembl chr 2:84,787,708...84,939,114
JBrowse link
G NPRL2 NPR2 like, GATOR1 complex subunit IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:39,005,699...39,009,183
Ensembl chr20:39,005,734...39,009,189
JBrowse link
G NPRL3 NPR3 like, GATOR1 complex subunit IBA
IEA
(PMID:21873635) GO_Central
Ensembl
InterPro
PMID:21873635 GO_REF:0000002, GO_REF:0000107 NCBI chr 6:40,351,757...40,394,599
Ensembl chr 6:40,352,477...40,390,489
JBrowse link
G PRKD1 protein kinase D1 ISO (PMID:22095288) ParkinsonsUK-UCL PMID:22095288 NCBI chr 8:9,004,641...9,327,054
Ensembl chr 8:9,005,115...9,328,358
JBrowse link
G RNF152 ring finger protein 152 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:14,914,508...15,001,843
Ensembl chr 1:14,985,769...14,986,380
JBrowse link
G RPS25 ribosomal protein S25 ISO RGD PMID:8144559 RGD:1304507 NCBI chr 5:14,833,804...14,836,376
Ensembl chr 5:14,833,918...14,836,749
JBrowse link
G RRAGA Ras related GTP binding A ISO (PMID:25936802) UniProtKB PMID:25936802 NCBI chr11:38,886,990...38,888,634
Ensembl chr11:38,886,397...38,888,184
JBrowse link
G RRAGB Ras related GTP binding B ISO (PMID:23723238) UniProtKB PMID:23723238 NCBI chr  X:47,323,427...47,361,551
Ensembl chr  X:47,323,269...47,361,138
JBrowse link
G RRAGC Ras related GTP binding C IEA Ensembl GO_REF:0000107 NCBI chr15:3,875,193...3,892,501
Ensembl chr15:3,874,116...3,892,504
JBrowse link
G SEH1L SEH1 like nucleoporin ISO (PMID:23723238) UniProtKB PMID:23723238 NCBI chr 7:78,352,153...78,383,546
Ensembl chr 7:78,351,992...78,541,669
JBrowse link
G SESN1 sestrin 1 IEA Ensembl GO_REF:0000107 NCBI chr12:65,958,995...66,057,369
Ensembl chr12:65,960,066...66,057,035
JBrowse link
G SESN2 sestrin 2 ISO (PMID:25263562) UniProtKB PMID:25263562 NCBI chr 2:72,151,464...72,168,861
Ensembl chr 2:72,151,868...72,168,492
JBrowse link
G SESN3 sestrin 3 IEA Ensembl GO_REF:0000107 NCBI chr21:5,827,957...5,899,540
Ensembl chr21:5,777,780...5,892,805
JBrowse link
G SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 ISO (PMID:21068542) UniProtKB PMID:21068542 NCBI chr 6:61,439,414...61,471,414
Ensembl chr 6:61,439,415...61,462,087
JBrowse link
G SLC38A2 solute carrier family 38 member 2 ISO RGD PMID:11311116 RGD:68721 NCBI chr27:8,056,289...8,068,988
Ensembl chr27:8,018,880...8,066,331
JBrowse link
G SZT2 SZT2 subunit of KICSTOR complex IEA Ensembl GO_REF:0000107 NCBI chr15:16,729,068...16,780,549
Ensembl chr15:16,728,758...16,780,325
JBrowse link
G TFEB transcription factor EB ISO (PMID:22343943), (PMID:22576015), (PMID:22692423) UniProt PMID:22343943, PMID:22576015, PMID:22692423 NCBI chr12:10,367,979...10,423,478
Ensembl chr12:10,368,599...10,452,619
JBrowse link
G UCP2 uncoupling protein 2 ISO glutamine RGD PMID:18692019 RGD:7240714 NCBI chr21:24,304,410...24,311,392
Ensembl chr21:24,304,457...24,311,128
JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 ISO (MGI:MGI:5607224|PMID:21855797) ParkinsonsUK-UCL PMID:21855797 MGI:MGI:5607224 NCBI chr26:968,714...982,244
Ensembl chr26:970,138...982,229
JBrowse link
G WDR24 WD repeat domain 24 IEA Ensembl GO_REF:0000107 NCBI chr 6:39,887,968...39,891,633
Ensembl chr 6:39,887,667...39,891,588
JBrowse link
G WDR59 WD repeat domain 59 IEA Ensembl GO_REF:0000107 NCBI chr 5:75,697,828...75,811,323
Ensembl chr 5:75,706,791...75,811,055
JBrowse link
cellular response to leucine starvation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 ISO (MGI:MGI:5494763|PMID:23447528) UniProtKB PMID:23447528 MGI:MGI:5494763 NCBI chr30:7,144,727...7,248,014
Ensembl chr30:7,144,570...7,248,000
JBrowse link
G GCN1 GCN1 activator of EIF2AK4 IEA Ensembl GO_REF:0000107 NCBI chr26:16,087,380...16,146,865
Ensembl chr26:16,087,382...16,146,813
JBrowse link
G IMPACT impact RWD domain protein IEA Ensembl GO_REF:0000107 NCBI chr 7:63,947,117...63,976,628
Ensembl chr 7:63,948,157...63,976,613
JBrowse link
G LARS1 leucyl-tRNA synthetase 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:40,544,031...40,619,268
Ensembl chr 2:40,544,210...40,635,281
JBrowse link
G MTOR mechanistic target of rapamycin kinase IEA Ensembl GO_REF:0000107 NCBI chr 2:84,818,893...84,939,283
Ensembl chr 2:84,787,708...84,939,114
JBrowse link
G RRAGB Ras related GTP binding B IEA Ensembl GO_REF:0000107 NCBI chr  X:47,323,427...47,361,551
Ensembl chr  X:47,323,269...47,361,138
JBrowse link
G RRAGD Ras related GTP binding D IEA Ensembl GO_REF:0000107 NCBI chr12:48,583,350...48,625,032
Ensembl chr12:48,585,937...48,625,130
JBrowse link
G SESN1 sestrin 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:65,958,995...66,057,369
Ensembl chr12:65,960,066...66,057,035
JBrowse link
G SESN2 sestrin 2 IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 2:72,151,464...72,168,861
Ensembl chr 2:72,151,868...72,168,492
JBrowse link
G SESN3 sestrin 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr21:5,827,957...5,899,540
Ensembl chr21:5,777,780...5,892,805
JBrowse link
regulation of eIF2 alpha phosphorylation by amino acid starvation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 IEA Ensembl GO_REF:0000107 NCBI chr30:7,144,727...7,248,014
Ensembl chr30:7,144,570...7,248,000
JBrowse link
G IMPACT impact RWD domain protein IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 7:63,947,117...63,976,628
Ensembl chr 7:63,948,157...63,976,613
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16187
    response to stimulus 8560
      response to stress 3628
        cellular response to stress 1897
          cellular response to starvation 176
            cellular response to amino acid starvation 50
              GCN2-mediated signaling 0
              cellular response to leucine starvation 10
              negative regulation of cellular response to amino acid starvation 0
              positive regulation of cellular response to amino acid starvation 0
              positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation 0
              regulation of cellular response to amino acid starvation + 0
              regulation of eIF2 alpha phosphorylation by amino acid starvation 2
Path 2
Term Annotations click to browse term
  biological_process 16187
    response to stimulus 8560
      response to external stimulus 2805
        response to extracellular stimulus 702
          response to nutrient levels 672
            response to starvation 239
              cellular response to starvation 176
                cellular response to amino acid starvation 50
                  GCN2-mediated signaling 0
                  cellular response to leucine starvation 10
                  negative regulation of cellular response to amino acid starvation 0
                  positive regulation of cellular response to amino acid starvation 0
                  positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation 0
                  regulation of cellular response to amino acid starvation + 0
                  regulation of eIF2 alpha phosphorylation by amino acid starvation 2
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.