Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:cellular response to amino acid starvation
go back to main search page
Accession:GO:0034198 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.
Synonyms:narrow_synonym: GAAC response;   general amino acid control response


show annotations for term's descendants           Sort by:
cellular response to amino acid starvation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 involved_in ISO (MGI:3722921|PMID:14729979) RGD PMID:14729979 MGI:3722921 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf4 activating transcription factor 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3582244|PMID:11106749), (MGI:3722921|PMID:14729979), (MGI:3798818|PMID:12667446)		 UniProt
RGD		 PMID:11106749 PMID:12667446 PMID:14729979 GO_REF:0000024 MGI:3582244 MGI:3722921 MGI:3798818 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Becn1 beclin 1 IEP RGD PMID:22835012 RGD:11561942 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bmt2 base methyltransferase of 25S rRNA 2 homolog involved_in ISO (PMID:29123071) RGD PMID:29123071 NCBI chr 4:41,881,630...41,945,472
Ensembl chr 4:41,879,993...41,945,539 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:26102367)
(MGI:5700278|PMID:26102367)		 RGD PMID:26102367 MGI:5700278 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Dap death-associated protein involved_in ISO
IBA		 (PMID:20537536)
PMID:21873635		 RGD PMID:20537536 PMID:21873635 RGD:13792537 NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752 		JBrowse link
G Dapl1 death associated protein-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:43,960,993...43,980,940
Ensembl chr 3:43,960,810...43,980,940 		JBrowse link
G Depdc5 DEP domain containing 5, GATOR1 subcomplex subunit involved_in ISO
IBA		 (PMID:23723238)
PMID:21873635		 RGD PMID:23723238 PMID:21873635 RGD:13792537 NCBI chr14:77,732,297...77,862,924
Ensembl chr14:77,732,297...77,862,794 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 involved_in ISO (PMID:25329545) RGD PMID:25329545 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:25329545)		 UniProt
RGD		 PMID:25329545 GO_REF:0000024 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISO (PMID:25329545)
(MGI:3722921|PMID:14729979), (MGI:5576818|PMID:24333428)		 RGD PMID:14729979 PMID:24333428 PMID:25329545 MGI:3722921 MGI:5576818 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha involved_in ISS
ISO		 GO_REF:0000024
(MGI:3582244|PMID:11106749)		 UniProt
RGD		 PMID:11106749 GO_REF:0000024 MGI:3582244 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Fas Fas cell surface death receptor involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Flcn folliculin involved_in ISO
ISS		 (PMID:24095279), (PMID:27113757), (PMID:31672913)
GO_REF:0000024		 RGD
UniProt		 PMID:24095279 PMID:27113757 PMID:31672913 GO_REF:0000024 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G Gcn1 GCN1 activator of EIF2AK4 involved_in ISO
IBA		 (MGI:5576818|PMID:24333428)
PMID:21873635		 RGD PMID:24333428 PMID:21873635 MGI:5576818, RGD:13792537 NCBI chr12:40,991,512...41,052,661
Ensembl chr12:40,991,512...41,052,555 		JBrowse link
G Hnrnpl heterogeneous nuclear ribonucleoprotein L IDA RGD PMID:19273590 RGD:9999430 NCBI chr 1:84,098,558...84,111,568
Ensembl chr 1:84,100,879...84,111,553 		JBrowse link
G Impact impact RWD domain protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:5576818|PMID:24333428)		 UniProt
RGD		 PMID:24333428 GO_REF:0000024 MGI:5576818 NCBI chr18:4,108,872...4,147,571
Ensembl chr18:4,108,853...4,147,569 		JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 involved_in ISO (PMID:28199306) RGD PMID:28199306 NCBI chr 4:161,684,249...161,698,315
Ensembl chr 4:161,684,249...161,698,422 		JBrowse link
G Kics2 KICSTOR subunit 2 involved_in IBA
ISO		 PMID:21873635
(PMID:28199306)		 RGD PMID:28199306 PMID:21873635 RGD:13792537 NCBI chr 7:57,284,213...57,299,070
Ensembl chr 7:57,284,192...57,297,486 		JBrowse link
G Kptn kaptin (actin binding protein) involved_in ISO (PMID:28199306) RGD PMID:28199306 NCBI chr 1:76,808,737...76,809,531 JBrowse link
G Lars1 leucyl-tRNA synthetase 1 involved_in ISO (PMID:22424946) RGD PMID:22424946 NCBI chr18:34,201,555...34,256,003
Ensembl chr18:34,201,549...34,255,931 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha IEP RGD PMID:22835012 RGD:11561942 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mios meiosis regulator for oocyte development involved_in ISO
IBA		 (PMID:23723238)
PMID:21873635		 RGD PMID:23723238 PMID:21873635 RGD:13792537 NCBI chr 4:36,263,419...36,289,546
Ensembl chr 4:36,263,968...36,289,544 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO
ISS		 (PMID:22343943), (PMID:22424946), (PMID:22576015), (PMID:22692423)
GO_REF:0000024		 RGD
UniProt		 PMID:22343943 PMID:22424946 PMID:22576015 PMID:22692423 GO_REF:0000024 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nprl2 NPR2-like, GATOR1 complex subunit involved_in ISO
IBA		 (PMID:23723238)
PMID:21873635		 RGD PMID:23723238 PMID:21873635 RGD:13792537 NCBI chr 8:108,215,823...108,218,996
Ensembl chr 8:108,215,814...108,218,996 		JBrowse link
G Nprl3 NPR3-like, GATOR1 complex subunit involved_in IBA
ISO		 PMID:21873635
(PMID:23723238)		 RGD PMID:23723238 PMID:21873635 RGD:13792537 NCBI chr10:15,355,361...15,395,812
Ensembl chr10:15,355,355...15,395,810 		JBrowse link
G Prkch protein kinase C, eta involved_in ISO (PMID:19797084) RGD PMID:19797084 NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654 		JBrowse link
G Prkd1 protein kinase D1 involved_in ISO (PMID:22095288) RGD PMID:22095288 NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042 		JBrowse link
G Rnf152 ring finger protein 152 involved_in IBA
ISO
ISS		 PMID:21873635
(MGI:5644195|PMID:25936802)
GO_REF:0000024
(PMID:25936802)		 RGD
UniProt		 PMID:25936802 PMID:21873635 GO_REF:0000024 MGI:5644195, RGD:13792537 NCBI chr13:21,324,039...21,403,405
Ensembl chr13:21,323,824...21,403,113 		JBrowse link
G Rpl17 ribosomal protein L17 IEP RGD PMID:8144559 RGD:1304507 NCBI chr18:68,581,147...68,584,253
Ensembl chr18:68,581,098...68,584,253 		JBrowse link
G Rps25 ribosomal protein s25 IEP RGD PMID:8144559 RGD:1304507 NCBI chr 8:44,733,623...44,735,999
Ensembl chr 8:44,733,029...44,737,271 		JBrowse link
G Rraga Ras-related GTP binding A involved_in ISS
ISO		 GO_REF:0000024
(PMID:25936802)		 UniProt
RGD		 PMID:25936802 GO_REF:0000024 NCBI chr 5:101,113,341...101,114,936
Ensembl chr 5:101,112,859...101,114,510 		JBrowse link
G RragB Ras-related GTP binding B involved_in ISO UniProtKB:Q9HB90 (PMID:23723238) RGD PMID:23723238 NCBI chr  X:18,184,619...18,234,639
Ensembl chr  X:18,184,992...18,234,639 		JBrowse link
G Rragc Ras-related GTP binding C involved_in ISO UniProtKB:Q5VZM2 (PMID:23723238) RGD PMID:23723238 NCBI chr 5:136,148,239...136,167,773
Ensembl chr 5:136,148,276...136,167,767 		JBrowse link
G Seh1l SEH1-like nucleoporin involved_in ISO (PMID:23723238) RGD PMID:23723238
G Sesn1 sestrin 1 involved_in ISO (PMID:25263562) RGD PMID:25263562 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697 		JBrowse link
G Sesn2 sestrin 2 involved_in ISO (PMID:25263562) RGD PMID:25263562 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Sesn3 sestrin 3 involved_in ISO (PMID:25263562) RGD PMID:25263562 NCBI chr 8:11,133,822...11,189,436
Ensembl chr 8:11,133,678...11,185,842 		JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 involved_in ISO (PMID:21068542) RGD PMID:21068542 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784 		JBrowse link
G Slc38a2 solute carrier family 38, member 2 IEP RGD PMID:11311116 RGD:68721 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436 		JBrowse link
G Szt2 SZT2 subunit of KICSTOR complex involved_in ISO (PMID:28199306), (PMID:28199315) RGD PMID:28199306 PMID:28199315 NCBI chr 5:131,897,250...131,943,953
Ensembl chr 5:131,897,275...131,943,904 		JBrowse link
G Tfeb transcription factor EB involved_in ISO (PMID:22343943), (PMID:22576015), (PMID:22692423) RGD PMID:22343943 PMID:22576015 PMID:22692423 NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714 		JBrowse link
G Ucp2 uncoupling protein 2 IEP glutamine RGD PMID:18692019 RGD:7240714 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 involved_in ISO UniProtKB:O70405 (MGI:5607224|PMID:21855797) RGD PMID:21855797 MGI:5607224 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966 		JBrowse link
G Wdr24 WD repeat domain 24 involved_in ISO
IBA		 (PMID:23723238)
PMID:21873635		 RGD PMID:23723238 PMID:21873635 RGD:13792537 NCBI chr10:14,844,089...14,848,871
Ensembl chr10:14,843,728...14,848,864 		JBrowse link
G Wdr59 WD repeat domain 59 involved_in ISO
IBA		 (PMID:23723238)
PMID:21873635		 RGD PMID:23723238 PMID:21873635 RGD:13792537 NCBI chr19:39,416,432...39,483,773
Ensembl chr19:39,416,429...39,483,698 		JBrowse link
cellular response to leucine starvation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 involved_in
acts_upstream_of_or_within_positive_effect		 ISO (PMID:17267404)
MGI:3720850 (MGI:5007596|PMID:21533046)		 RGD PMID:17267404 PMID:21533046 MGI:5007596 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Atf4 activating transcription factor 4 involved_in ISO (MGI:3710913|PMID:17267404)
(PMID:17267404)		 RGD PMID:17267404 MGI:3710913 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISO (MGI:5494763|PMID:23447528) RGD PMID:23447528 MGI:5494763 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G Gcn1 GCN1 activator of EIF2AK4 involved_in ISO (MGI:5494763|PMID:23447528) RGD PMID:23447528 MGI:5494763 NCBI chr12:40,991,512...41,052,661
Ensembl chr12:40,991,512...41,052,555 		JBrowse link
G Impact impact RWD domain protein involved_in ISO
ISS		 (MGI:5494763|PMID:23447528)
GO_REF:0000024		 RGD
UniProt		 PMID:23447528 GO_REF:0000024 MGI:5494763 NCBI chr18:4,108,872...4,147,571
Ensembl chr18:4,108,853...4,147,569 		JBrowse link
G Lars1 leucyl-tRNA synthetase 1 involved_in ISO (PMID:22424946) RGD PMID:22424946 NCBI chr18:34,201,555...34,256,003
Ensembl chr18:34,201,549...34,255,931 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO (PMID:22424946) RGD PMID:22424946 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Rnf167 ring finger protein 167 involved_in ISS
ISO		 GO_REF:0000024
(PMID:35114100)		 UniProt
RGD		 PMID:35114100 GO_REF:0000024 NCBI chr10:55,360,603...55,364,927
Ensembl chr10:55,360,543...55,364,927 		JBrowse link
G RragB Ras-related GTP binding B involved_in ISO (PMID:22424946) RGD PMID:22424946 NCBI chr  X:18,184,619...18,234,639
Ensembl chr  X:18,184,992...18,234,639 		JBrowse link
G Rragd Ras-related GTP binding D involved_in ISO (PMID:22424946) RGD PMID:22424946 NCBI chr 5:47,373,902...47,409,369
Ensembl chr 5:47,373,463...47,409,356 		JBrowse link
G Sesn1 sestrin 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697 		JBrowse link
G Sesn2 sestrin 2 involved_in IBA
ISO		 PMID:21873635
(PMID:26449471), (PMID:35114100)		 RGD PMID:26449471 PMID:35114100 PMID:21873635 RGD:13792537 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Sesn3 sestrin 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:11,133,822...11,189,436
Ensembl chr 8:11,133,678...11,185,842 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19740
    response to stimulus 10464
      response to stress 4239
        cellular response to stress 2122
          cellular response to starvation 211
            cellular response to amino acid starvation 53
              cellular response to leucine starvation 13
              negative regulation of cellular response to amino acid starvation 0
              positive regulation of cellular response to amino acid starvation 0
              regulation of cellular response to amino acid starvation + 0
Path 2
Term Annotations click to browse term
  biological_process 19740
    response to stimulus 10464
      response to external stimulus 3254
        response to extracellular stimulus 838
          response to nutrient levels 807
            response to starvation 276
              cellular response to starvation 211
                cellular response to amino acid starvation 53
                  cellular response to leucine starvation 13
                  negative regulation of cellular response to amino acid starvation 0
                  positive regulation of cellular response to amino acid starvation 0
                  regulation of cellular response to amino acid starvation + 0
paths to the root