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ONTOLOGY REPORT - ANNOTATIONS

Term:purine nucleoside bisphosphate biosynthetic process
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Accession:GO:0034033 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
Synonyms:exact_synonym: purine nucleoside bisphosphate anabolism;   purine nucleoside bisphosphate biosynthesis;   purine nucleoside bisphosphate formation;   purine nucleoside bisphosphate synthesis


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3'-phosphoadenosine 5'-phosphosulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Papss1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:14747722), (PMID:23207770)
(MGI:1202528|PMID:9545271), (MGI:77543|PMID:7493984)
PMID:21873635
(MGI:2448448|PMID:12414806)		 RGD PMID:7493984 PMID:9545271 PMID:12414806 PMID:14747722 PMID:23207770 More... MGI:1202528 MGI:2448448 MGI:77543, RGD:13792537 NCBI chr 2:220,040,338...220,114,399
Ensembl chr 2:220,040,312...220,114,395 		JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 involved_in ISO
IBA		 (PMID:23824674)
MGI:1856688 (MGI:1277343|PMID:9671738), (MGI:1347713|PMID:10559207)
PMID:21873635		 RGD PMID:9671738 PMID:10559207 PMID:23824674 PMID:21873635 MGI:1277343 MGI:1347713, RGD:13792537 NCBI chr 1:230,454,314...230,539,332
Ensembl chr 1:230,454,426...230,539,331 		JBrowse link
acetyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:17371050) RGD PMID:17371050 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Acly ATP citrate lyase involved_in NAS
IEA
ISO
IBA		 GO_REF:0000107
(PMID:1371749)
PMID:21873635
GO_REF:0000002		 Ensembl
RGD
InterPro		 PMID:1371749 PMID:2295639 PMID:21873635 GO_REF:0000002 GO_REF:0000107, RGD:631761, RGD:13792537 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:16788062)
PMID:21873635
(MGI:2151932|PMID:11150295)		 RGD PMID:11150295 PMID:16788062 PMID:21873635 MGI:2151932, RGD:13792537 NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:2151932|PMID:11150295)
PMID:21873635		 RGD PMID:11150295 PMID:21873635 MGI:2151932, RGD:13792537 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675 		JBrowse link
G Dip2a disco-interacting protein 2 homolog A involved_in ISO (MGI:6478983|PMID:30672040) RGD PMID:30672040 MGI:6478983 NCBI chr20:12,284,566...12,371,068
Ensembl chr20:12,284,654...12,370,217 		JBrowse link
G Mlycd malonyl-CoA decarboxylase involved_in IDA
IEA
ISO
IBA		 GO_REF:0000041
(PMID:10417274), (PMID:10455107), (PMID:9869665)
PMID:21873635		 UniProt
RGD		 PMID:9869665 PMID:10417274 PMID:10455107 PMID:17316539 PMID:21873635 GO_REF:0000041, RGD:1600790, RGD:13792537 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793 		JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase involved_in ISO (PMID:29754768) RGD PMID:29754768 NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933 		JBrowse link
acetyl-CoA biosynthetic process from acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acss1 acyl-CoA synthetase short-chain family member 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325 		JBrowse link
acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlat dihydrolipoamide S-acetyltransferase involved_in IDA
ISO		 MGI:2386703 (MGI:3719938|PMID:17314311), (MGI:5819147|PMID:27621431)
(PMID:24534072)		 RGD PMID:17314311 PMID:24534072 PMID:27621431 PMID:7487891 MGI:3719938 MGI:5819147, RGD:1599112 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479 		JBrowse link
G Dlat-ps1 dihydrolipoamide S-acetyltransferase, pseudogene 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:33,231,211...33,233,823
Ensembl chr 1:33,231,226...33,233,129 		JBrowse link
G Dld dihydrolipoamide dehydrogenase involved_in IDA
ISO		 MGI:2386703 (MGI:3719938|PMID:17314311), (MGI:5819147|PMID:27621431)
(PMID:24534072)		 RGD PMID:17314311 PMID:24534072 PMID:27621431 PMID:7487891 MGI:3719938 MGI:5819147, RGD:1599112 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795 		JBrowse link
G Mpc1 mitochondrial pyruvate carrier 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:5428352|PMID:22628558) RGD PMID:22628558 MGI:5428352 NCBI chr 1:52,437,745...52,449,369
Ensembl chr 1:52,437,741...52,449,400 		JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 acts_upstream_of_or_within
involved_in		 ISO MGI:5635078 (MGI:5428352|PMID:22628558), (MGI:5576400|PMID:24910426) RGD PMID:22628558 PMID:24910426 MGI:5428352 MGI:5576400 NCBI chr13:77,728,176...77,747,664
Ensembl chr13:77,728,250...77,747,664 		JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 involved_in
acts_upstream_of_or_within		 IDA
IBA
ISO
IEA		 PMID:21873635
GO_REF:0000114
MGI:2182095|MGI:2386703 (MGI:3817854|PMID:18586888)
(PMID:19081061), (PMID:24534072)
GO_REF:0000002		 ComplexPortal
RGD
InterPro		 PMID:18586888 PMID:19081061 PMID:24534072 PMID:7487891 PMID:21873635 GO_REF:0000002 GO_REF:0000114 MGI:3817854, RGD:1599112, RGD:13792537 NCBI chr  X:34,700,481...34,714,309
Ensembl chr  X:34,700,409...34,714,311 		JBrowse link
G Pdha1l1 pyruvate dehydrogenase (lipoamide) alpha 1-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:82,511,483...82,514,378
Ensembl chr16:82,511,511...82,514,372 		JBrowse link
G Pdha2 pyruvate dehydrogenase E1 subunit alpha 2 involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:7487891 PMID:21873635 RGD:1599112, RGD:13792537 NCBI chr 2:229,872,300...229,873,848 JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta involved_in IDA
ISO
IEA
IBA		 GO_REF:0000114
GO_REF:0000002
(PMID:19081061), (PMID:24534072)
GO_REF:0000107
PMID:21873635		 ComplexPortal
InterPro
RGD
Ensembl		 PMID:19081061 PMID:24534072 PMID:7487891 PMID:21873635 GO_REF:0000002 GO_REF:0000107 GO_REF:0000114, RGD:1599112, RGD:13792537 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500 		JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X involved_in ISO (PMID:24534072) RGD PMID:24534072 NCBI chr 3:89,372,472...89,396,759
Ensembl chr 3:89,371,497...89,431,773 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 TAS RGD PMID:12435272 RGD:729541 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
coenzyme A biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:17371050) RGD PMID:17371050 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Acot7 acyl-CoA thioesterase 7 involved_in ISO (PMID:10578051) RGD PMID:10578051 NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309 		JBrowse link
G Coasy Coenzyme A synthase involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:11923312)
PMID:21873635
(MGI:2181228|PMID:11980892)		 RGD PMID:11923312 PMID:11980892 PMID:21873635 MGI:2181228, RGD:13792537 NCBI chr10:86,014,566...86,018,849
Ensembl chr10:86,014,597...86,018,841 		JBrowse link
G Dcakd dephospho-CoA kinase domain containing involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:87,957,738...87,989,002
Ensembl chr10:87,957,740...87,980,054 		JBrowse link
G Pank1 pantothenate kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2176050|MGI:4462018 (MGI:4461354|PMID:20559429), (MGI:5446555|PMID:22815849)
PMID:21873635
(MGI:3607004|PMID:16040613)		 RGD PMID:16040613 PMID:20559429 PMID:22815849 PMID:21873635 MGI:3607004 MGI:4461354 MGI:5446555, RGD:13792537 NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829 		JBrowse link
G Pank2 pantothenate kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2176050|MGI:5446719 (MGI:5446555|PMID:22815849)
PMID:21873635		 RGD PMID:22815849 PMID:21873635 MGI:5446555, RGD:13792537 NCBI chr 3:118,483,382...118,519,551
Ensembl chr 3:118,483,444...118,518,320 		JBrowse link
G Pank3 pantothenate kinase 3 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:20797618), (PMID:30927326)
PMID:21873635
(MGI:3607004|PMID:16040613)		 RGD PMID:16040613 PMID:20797618 PMID:30927326 PMID:21873635 MGI:3607004, RGD:13792537 NCBI chr10:20,229,129...20,252,955
Ensembl chr10:20,229,129...20,252,955 		JBrowse link
G Pank4 pantothenate kinase 4 involved_in IEA
IBA		 GO_REF:0000104
PMID:21873635		 UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 5:165,525,340...165,542,139
Ensembl chr 5:165,525,402...165,542,135 		JBrowse link
G Ppcdc phosphopantothenoylcysteine decarboxylase involved_in IBA
ISO		 PMID:21873635
(PMID:11923312)		 RGD PMID:11923312 PMID:21873635 RGD:13792537 NCBI chr 8:57,815,195...57,842,863
Ensembl chr 8:57,815,195...58,000,570 		JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase involved_in ISO
IBA		 (PMID:11923312), (PMID:29754768)
PMID:21873635		 RGD PMID:11923312 PMID:29754768 PMID:21873635 RGD:13792537 NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933 		JBrowse link
G Taf9 TATA-box binding protein associated factor 9 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769 		JBrowse link
fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gcdh glutaryl-CoA dehydrogenase involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:6895440 PMID:21873635 RGD:1598697, RGD:13792537 NCBI chr19:23,263,215...23,269,689
Ensembl chr19:23,263,264...23,269,681 		JBrowse link
long-chain fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long-chain family member 1 involved_in IGI
IBA		 PMID:21873635 RGD
GO_Central		 PMID:16466685 PMID:21873635 RGD:2312800, RGD:13792537 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 IGI RGD PMID:16466685 RGD:2312800 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 involved_in IGI
IBA		 PMID:21873635 RGD
GO_Central		 PMID:16466685 PMID:21873635 RGD:2312800, RGD:13792537 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607 		JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 involved_in IGI
IBA		 PMID:21873635 RGD
GO_Central		 PMID:16466685 PMID:21873635 RGD:2312800, RGD:13792537 NCBI chr10:38,439,914...38,501,182
Ensembl chr10:38,440,080...38,498,757 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958 		JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115 		JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 8:84,702,916...84,729,466
Ensembl chr 8:84,702,362...84,729,697 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 8:78,790,799...78,857,307
Ensembl chr 8:78,790,846...78,857,284 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186 		JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:39,789,250...39,856,845 		JBrowse link
malonyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acacb acetyl-CoA carboxylase beta involved_in IEA
ISO		 GO_REF:0000041
(MGI:3804564|PMID:18487439)		 UniProt
RGD		 PMID:18487439 GO_REF:0000041 MGI:3804564 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655 		JBrowse link
propionyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:17371050) RGD PMID:17371050 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdk1 pyruvate dehydrogenase kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5487511|PMID:22195962)		 Ensembl
RGD		 PMID:22195962 GO_REF:0000107 MGI:5487511 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 involved_in ISO
ISS		 (MGI:5428826|PMID:22360721)
GO_REF:0000024		 RGD
UniProt		 PMID:22360721 GO_REF:0000024 MGI:5428826 NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085 		JBrowse link
G Pdk3 pyruvate dehydrogenase kinase 3 involved_in ISO (PMID:22865452) RGD PMID:22865452 NCBI chr  X:58,477,471...58,553,932
Ensembl chr  X:58,486,554...58,553,557 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 involved_in ISO
ISS		 (PMID:21852536)
(MGI:3692363|PMID:16606348)
GO_REF:0000024		 RGD
UniProt		 PMID:16606348 PMID:21852536 GO_REF:0000024 MGI:3692363 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snca synuclein alpha acts_upstream_of_or_within ISO MGI:2389489 (MGI:3628986|PMID:16636270), (MGI:3629421|PMID:16734431) RGD PMID:16636270 PMID:16734431 MGI:3628986 MGI:3629421 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
succinyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmut methylmalonyl-CoA mutase involved_in ISO (MGI:64406|PMID:7904153) RGD PMID:7904153 MGI:64406 NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    metabolic process 12010
      cellular metabolic process 7444
        cellular aromatic compound metabolic process 3032
          purine-containing compound metabolic process 466
            purine nucleoside bisphosphate metabolic process 113
              purine nucleoside bisphosphate biosynthetic process 47
                acyl-CoA biosynthetic process + 36
                coenzyme A biosynthetic process + 11
                purine ribonucleoside bisphosphate biosynthetic process + 2
Path 2
Term Annotations click to browse term
  biological_process 19738
    metabolic process 12010
      cellular metabolic process 7444
        cellular aromatic compound metabolic process 3032
          nucleobase-containing compound metabolic process 2783
            nucleobase-containing small molecule metabolic process 570
              nucleoside phosphate metabolic process 498
                nucleoside bisphosphate metabolic process 113
                  nucleoside bisphosphate biosynthetic process 47
                    purine nucleoside bisphosphate biosynthetic process 47
                      acyl-CoA biosynthetic process + 36
                      coenzyme A biosynthetic process + 11
                      purine ribonucleoside bisphosphate biosynthetic process + 2
paths to the root