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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:ribonucleoside bisphosphate biosynthetic process
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Accession:GO:0034030 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
Synonyms:exact_synonym: ribonucleoside bisphosphate anabolism;   ribonucleoside bisphosphate biosynthesis;   ribonucleoside bisphosphate formation;   ribonucleoside bisphosphate synthesis



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ribonucleoside bisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COASY Coenzyme A synthase involved_in IEA UniProt GO_REF:0000117 NCBI chr17:14,750,246...14,754,417
Ensembl chr17:14,973,662...14,977,797
JBrowse link
G PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr 4:100,119,540...100,225,575
Ensembl chr 4:110,692,601...110,798,619
JBrowse link
G PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 involved_in IEA UniProt GO_REF:0000117 NCBI chr10:84,383,936...84,471,745
Ensembl chr10:87,890,631...87,977,839
JBrowse link
3'-phosphoadenosine 5'-phosphosulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2448448|PMID:12414806) MGI
Ensembl
PMID:12414806 GO_REF:0000107 MGI:2448448 NCBI chr 4:100,119,540...100,225,575
Ensembl chr 4:110,692,601...110,798,619
JBrowse link
G PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:84,383,936...84,471,745
Ensembl chr10:87,890,631...87,977,839
JBrowse link
acetyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:103,008,564...103,034,697
Ensembl chr11:106,483,563...106,509,787
JBrowse link
G ACLY ATP citrate lyase involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chr17:15,385,335...15,447,269
Ensembl chr17:15,615,994...15,664,800
JBrowse link
G ACSS1 acyl-CoA synthetase short chain family member 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2151932|PMID:11150295) MGI
Ensembl
PMID:11150295 GO_REF:0000107 MGI:2151932 NCBI chr20:24,946,629...25,001,311
Ensembl chr20:25,293,511...25,349,017
JBrowse link
G ACSS2 acyl-CoA synthetase short chain family member 2 acts_upstream_of_or_within ISO (MGI:2151932|PMID:11150295) MGI PMID:11150295 MGI:2151932 NCBI chr20:31,205,104...31,256,263
Ensembl chr20:32,329,721...32,380,526
JBrowse link
G DIP2A disco interacting protein 2 homolog A involved_in ISO (MGI:6478983|PMID:30672040) UniProt PMID:30672040 MGI:6478983 NCBI chr21:32,921,019...33,034,988
Ensembl chr21:46,060,713...46,168,885
JBrowse link
G MLYCD malonyl-CoA decarboxylase involved_in ISO
IEA
RGD
Ensembl
PMID:17316539 GO_REF:0000107 RGD:1600790 NCBI chr16:64,520,860...64,537,955
Ensembl chr16:83,912,793...83,929,162
JBrowse link
G PPCS phosphopantothenoylcysteine synthetase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:41,756,403...41,773,430
Ensembl chr 1:43,136,720...43,140,620
JBrowse link
acetyl-CoA biosynthetic process from acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSS1 acyl-CoA synthetase short chain family member 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr20:24,946,629...25,001,311
Ensembl chr20:25,293,511...25,349,017
JBrowse link
acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLAT dihydrolipoamide S-acetyltransferase involved_in ISO
IEA
RGD
Ensembl
InterPro
PMID:7487891 GO_REF:0000002 GO_REF:0000107 RGD:1599112 NCBI chr11:106,910,857...106,950,851
Ensembl chr11:110,756,001...110,792,795
JBrowse link
G DLD dihydrolipoamide dehydrogenase involved_in ISO
IEA
RGD
Ensembl
PMID:7487891 GO_REF:0000107 RGD:1599112 NCBI chr 7:99,872,020...99,901,884
Ensembl chr 7:112,593,934...112,623,629
JBrowse link
G MPC1 mitochondrial pyruvate carrier 1 involved_in
acts_upstream_of_or_within
ISO (MGI:5428352|PMID:22628558) MGI PMID:22628558 MGI:5428352 NCBI chr 6:164,331,604...164,349,747 JBrowse link
G MPC2 mitochondrial pyruvate carrier 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5576400|PMID:24910426)
(MGI:5428352|PMID:22628558)
MGI
Ensembl
PMID:22628558 PMID:24910426 GO_REF:0000107 MGI:5428352 MGI:5576400 NCBI chr 1:143,406,611...143,424,508
Ensembl chr 1:147,132,213...147,151,648
JBrowse link
G PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 involved_in
acts_upstream_of_or_within
ISO
IEA
(MGI:3817854|PMID:18586888) RGD
Ensembl
MGI
InterPro
PMID:7487891 PMID:18586888 GO_REF:0000002 GO_REF:0000107 MGI:3817854 RGD:1599112 NCBI chr  X:11,967,944...11,985,837
Ensembl chr  X:19,330,508...19,348,443
JBrowse link
G PDHA2 pyruvate dehydrogenase E1 subunit alpha 2 ISO RGD PMID:7487891 RGD:1599112 NCBI chr 4:88,213,492...88,216,451
Ensembl chr 4:98,883,109...98,884,853
JBrowse link
G PDHB pyruvate dehydrogenase E1 subunit beta involved_in ISO
IEA
RGD
Ensembl
InterPro
PMID:7487891 GO_REF:0000002 GO_REF:0000107 RGD:1599112 NCBI chr 3:58,359,753...58,366,094
Ensembl chr 3:59,776,618...59,782,411
JBrowse link
G PDHX pyruvate dehydrogenase complex component X involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chr11:34,889,242...34,968,886
Ensembl chr11:34,764,450...34,844,166
JBrowse link
coenzyme A biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:103,008,564...103,034,697
Ensembl chr11:106,483,563...106,509,787
JBrowse link
G ACOT7 acyl-CoA thioesterase 7 involved_in ISO (PMID:10578051) BHF-UCL PMID:10578051 NCBI chr 1:5,030,488...5,154,800 JBrowse link
G COASY Coenzyme A synthase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2181228|PMID:11980892) MGI
InterPro
Ensembl
PMID:11980892 GO_REF:0000002 GO_REF:0000107 MGI:2181228 NCBI chr17:14,750,246...14,754,417
Ensembl chr17:14,973,662...14,977,797
JBrowse link
G DCAKD dephospho-CoA kinase domain containing involved_in IEA InterPro GO_REF:0000002 NCBI chr17:12,266,199...12,299,502
Ensembl chr17:12,440,194...12,473,099
JBrowse link
G PANK1 pantothenate kinase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3607004|PMID:16040613)
(MGI:4461354|PMID:20559429), (MGI:5446555|PMID:22815849)
MGI
InterPro
PMID:16040613 PMID:20559429 PMID:22815849 GO_REF:0000002 MGI:3607004 MGI:4461354 MGI:5446555 NCBI chr10:86,302,702...86,428,635
Ensembl chr10:89,847,888...89,912,765
JBrowse link
G PANK2 pantothenate kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5446555|PMID:22815849) InterPro
MGI
Ensembl
PMID:22815849 GO_REF:0000002 GO_REF:0000107 MGI:5446555 NCBI chr20:3,924,054...3,959,393
Ensembl chr20:3,723,211...3,757,748
JBrowse link
G PANK3 pantothenate kinase 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3607004|PMID:16040613) MGI
Ensembl
InterPro
PMID:16040613 GO_REF:0000002 GO_REF:0000107 MGI:3607004 NCBI chr 5:163,913,842...163,944,939
Ensembl chr 5:170,685,413...170,709,211
JBrowse link
G PANK4 pantothenate kinase 4 (inactive) involved_in IEA UniProt
InterPro
GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 NCBI chr 1:1,238,821...1,259,139
Ensembl chr 1:2,378,116...2,395,738
JBrowse link
G PPCDC phosphopantothenoylcysteine decarboxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:53,963,001...54,001,550
Ensembl chr15:73,579,583...73,606,834
JBrowse link
G PPCS phosphopantothenoylcysteine synthetase involved_in IEA Ensembl
UniProt
GO_REF:0000107 GO_REF:0000117 NCBI chr 1:41,756,403...41,773,430
Ensembl chr 1:43,136,720...43,140,620
JBrowse link
fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCDH glutaryl-CoA dehydrogenase ISO RGD PMID:6895440 RGD:1598697 NCBI chr19:12,452,779...12,461,757
Ensembl chr19:13,195,241...13,204,223
JBrowse link
long-chain fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL1 acyl-CoA synthetase long chain family member 1 ISO RGD PMID:16466685 RGD:2312800 NCBI chr 4:176,920,811...176,991,495
Ensembl chr 4:189,145,403...189,198,646
JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 ISO RGD PMID:16466685 RGD:2312800 NCBI chr  X:98,731,109...98,841,067
Ensembl chr  X:109,206,964...109,310,914
JBrowse link
G ACSL5 acyl-CoA synthetase long chain family member 5 ISO RGD PMID:16466685 RGD:2312800 NCBI chr10:108,965,559...109,019,240
Ensembl chr10:112,407,161...112,457,892
JBrowse link
G ACSL6 acyl-CoA synthetase long chain family member 6 ISO RGD PMID:16466685 RGD:2312800 NCBI chr 5:127,373,306...127,434,954
Ensembl chr 5:133,537,292...133,586,711
JBrowse link
G ELOVL1 ELOVL fatty acid elongase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr 1:42,664,818...42,686,475
Ensembl chr 1:44,044,693...44,048,769
JBrowse link
G ELOVL3 ELOVL fatty acid elongase 3 involved_in IEA UniProt GO_REF:0000104 NCBI chr10:98,788,505...98,833,146
Ensembl chr10:102,297,291...102,300,594
JBrowse link
G ELOVL4 ELOVL fatty acid elongase 4 involved_in IEA UniProt GO_REF:0000104 NCBI chr 6:77,798,058...77,830,840
Ensembl chr 6:81,068,882...81,102,050
JBrowse link
G ELOVL5 ELOVL fatty acid elongase 5 involved_in IEA UniProt GO_REF:0000104 NCBI chr 6:52,822,038...52,902,122
Ensembl chr 6:54,451,887...54,485,878
JBrowse link
G ELOVL6 ELOVL fatty acid elongase 6 involved_in IEA UniProt GO_REF:0000104 NCBI chr 4:102,545,815...102,695,536
Ensembl chr 4:113,110,466...113,260,444
JBrowse link
G ELOVL7 ELOVL fatty acid elongase 7 involved_in IEA UniProt GO_REF:0000104 NCBI chr 5:53,156,518...53,248,839
Ensembl chr 5:54,853,330...54,888,930
JBrowse link
malonyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACA acetyl-CoA carboxylase alpha involved_in IEA UniProt GO_REF:0000041 NCBI chr17:19,670,114...19,998,903
Ensembl chr17:19,969,205...20,297,651
JBrowse link
G ACACB acetyl-CoA carboxylase beta involved_in IEA Ensembl
UniProt
GO_REF:0000041 GO_REF:0000107 NCBI chr12:106,692,668...106,845,490
Ensembl chr12:110,086,374...110,239,847
JBrowse link
propionyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:103,008,564...103,034,697
Ensembl chr11:106,483,563...106,509,787
JBrowse link
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDK1 pyruvate dehydrogenase kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:59,841,840...59,958,504
Ensembl chr2B:177,297,840...177,341,113
JBrowse link
G PDK2 pyruvate dehydrogenase kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:44,185,463...44,202,221
Ensembl chr17:49,060,030...49,076,115
JBrowse link
G PDK3 pyruvate dehydrogenase kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:17,062,278...17,147,489
Ensembl chr  X:24,430,028...24,504,730
JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:87,540,600...87,553,673
Ensembl chr 7:101,128,060...101,141,157
JBrowse link
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNCA synuclein alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3629421|PMID:16734431)
(MGI:3628986|PMID:16636270)
MGI
Ensembl
PMID:16636270 PMID:16734431 GO_REF:0000107 MGI:3628986 MGI:3629421 NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600
JBrowse link
succinyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MMUT methylmalonyl-CoA mutase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:49,007,500...49,040,470
Ensembl chr 6:50,269,644...50,302,593
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15441
    metabolic process 10054
      organic substance metabolic process 9678
        organophosphate metabolic process 813
          nucleoside phosphate metabolic process 425
            nucleoside bisphosphate metabolic process 100
              nucleoside bisphosphate biosynthetic process 44
                ribonucleoside bisphosphate biosynthetic process 44
                  acyl-CoA biosynthetic process + 34
                  coenzyme A biosynthetic process + 10
                  purine ribonucleoside bisphosphate biosynthetic process + 2
Path 2
Term Annotations click to browse term
  biological_process 15441
    metabolic process 10054
      cellular metabolic process 6052
        cellular aromatic compound metabolic process 2552
          nucleobase-containing compound metabolic process 2325
            nucleobase-containing small molecule metabolic process 482
              nucleoside phosphate metabolic process 425
                nucleoside bisphosphate metabolic process 100
                  nucleoside bisphosphate biosynthetic process 44
                    ribonucleoside bisphosphate biosynthetic process 44
                      acyl-CoA biosynthetic process + 34
                      coenzyme A biosynthetic process + 10
                      purine ribonucleoside bisphosphate biosynthetic process + 2
paths to the root