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ONTOLOGY REPORT - ANNOTATIONS

Term:ribonuclease T2 activity
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Accession:GO:0033897 term browser browse the term
Definition:Catalysis of the reaction: a ribonucleotidyl-ribonucleotide-RNA + H2O = a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + H+. This reaction is a two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.
Synonyms:exact_synonym: Escherichia coli ribonuclease I' ribonuclease PP2 activity;   RNAase CL activity;   RNase (non-base specific) activity;   RNase Ms activity;   acid RNase activity;   acid ribonuclease activity;   nonbase-specific RNase activity;   nonspecific RNase activity;   ribonnuclease (non-base specific) activity;   ribonuclease M activity;   ribonuclease N2 activity;   ribonuclease U4 activity;   ribonucleate 3'-oligonucleotide hydrolase activity
 broad_synonym: RNase II activity;   ribonuclease II activity;   ribonucleate nucleotido-2'-transferase (cyclizing) activity
 related_synonym: Escherichia coli ribonuclease II activity;   RNase M activity;   RNase T2 activity;   ribonuclease (non-base specific) activity;   ribonuclease PP3 activity
 xref: EC:4.6.1.19;   MetaCyc:3.1.27.5-RXN;   RHEA:68052


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ribonuclease T2 activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnaset2 ribonuclease T2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:52,576,344...52,603,151
Ensembl chr 1:52,585,929...52,603,147 		JBrowse link
G Rnaset2-ps1 ribonuclease T2, pseudogene 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:138,600,084...138,600,943
Ensembl chr 3:138,600,187...138,600,965
Ensembl chr 3:138,600,187...138,600,965 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20732
    catalytic activity 6109
      lyase activity 210
        phosphorus-oxygen lyase activity 27
          ribonuclease T2 activity 2
Path 2
Term Annotations click to browse term
  molecular_function 20732
    catalytic activity 6109
      hydrolase activity 2595
        hydrolase activity, acting on ester bonds 811
          nuclease activity 229
            endonuclease activity 134
              RNA endonuclease activity 73
                ribonuclease T2 activity 2
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