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ONTOLOGY REPORT - ANNOTATIONS

Term:3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity
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Accession:GO:0033791 term browser browse the term
Definition:Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor.
Synonyms:related_synonym: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA:acceptor 24-oxidoreductase (24R-hydroxylating) activity;   3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate 24-hydroxylase activity;   3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA oxidase activity;   THC-CoA oxidase activity;   THCA-CoA oxidase activity;   trihydroxycoprostanoyl-CoA oxidase activity
 xref: EC:1.17.99.3;   MetaCyc:1.17.99.3-RXN;   RHEA:15733


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3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox2 acyl-Coenzyme A oxidase 2, branched chain enables ISO
IBA		 MGI
RGD
GO_Central		 PMID:1400324 PMID:8654595 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:2299949 RGD:2299971 NCBI chr14:14,210,406...14,244,262
Ensembl chr14:14,210,420...14,244,262 		JBrowse link
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  molecular_function 28827
    catalytic activity 5720
      oxidoreductase activity 792
        oxidoreductase activity, acting on CH or CH2 groups 16
          3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity 1
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