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ONTOLOGY REPORT - ANNOTATIONS


Term:3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity
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Accession:GO:0033791 term browser browse the term
Definition:Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor.
Synonyms:related_synonym: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA:acceptor 24-oxidoreductase (24R-hydroxylating) activity;   3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate 24-hydroxylase activity;   3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA oxidase activity;   THC-CoA oxidase activity;   THCA-CoA oxidase activity;   trihydroxycoprostanoyl-CoA oxidase activity
 xref: EC:1.17.99.3;   MetaCyc:1.17.99.3-RXN;   RHEA:15733



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3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox2 acyl-CoA oxidase 2 enables IDA
IBA
ISO
PMID:21873635
(PMID:27884763)
RGD PMID:27884763 PMID:1400324 PMID:8654595 PMID:21873635 RGD:2299949, RGD:2299971, RGD:13792537 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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  molecular_function 20773
    catalytic activity 6045
      oxidoreductase activity 870
        oxidoreductase activity, acting on CH or CH2 groups 12
          3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity 1
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