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ONTOLOGY REPORT - ANNOTATIONS

Term:indoleamine 2,3-dioxygenase activity
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Accession:GO:0033754 term browser browse the term
Definition:Catalysis of the reaction: tryptophan + O2 = N-formylkynurenine. The product of the reaction depends on the substrate; D-tryptophan produces N-formyl-D-kynurenine, and L-tryptophan produces N-formyl-L-kynurenine.
Synonyms:narrow_synonym: D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) activity
 broad_synonym: tryptophan pyrrolase activity
 related_synonym: IDO
 xref: EC:1.13.11.52;   MetaCyc:RXN-8664;   MetaCyc:RXN-8665;   RHEA:14189


show annotations for term's descendants           Sort by:
indoleamine 2,3-dioxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ido1 indoleamine 2,3-dioxygenase 1 enables IDA
ISO
IEA
IBA		 (PMID:25310899)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000118		 RGD
Ensembl
GO_Central
TreeGrafter		 PMID:25310899 PMID:10719243 PMID:3400092 PMID:11513477 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118, RGD:2290190, RGD:2290313, RGD:2290543 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 enables IEA
ISO
IBA		 GO_REF:0000107
(PMID:17671174)
GO_REF:0000033
(PMID:17499941), (PMID:17671174)		 Ensembl
RGD
GO_Central		 PMID:17499941 PMID:17671174 GO_REF:0000033 GO_REF:0000107 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    catalytic activity 6145
      oxidoreductase activity 871
        dioxygenase activity 99
          oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 28
            indoleamine 2,3-dioxygenase activity 2
paths to the root