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ONTOLOGY REPORT - ANNOTATIONS


Term:Rpd3L complex
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Accession:GO:0033698 term browser browse the term
Definition:A histone deacetylase complex which deacetylates histones preferentially in promoter regions. Composed of a two copies of catalytic histone deacetylase subunit (S. pombe Clr6/ S. cerevisiae Rpd3p), an Sds-3 family protein (S. pombe /S. cerevisiae Sds3(p) ), two copies of SIN3 family co-repressor (S. pombe Pst1/ S. cerevisiae Sin3p, a WD repeat protein/ histone chaperone (S. pombe Prw1/ S. cerevisiae Ume1p), and a zf- PHD finger ( S. pombe Png2/ S. cerevisiae Pho23p), plus 4 additional subunits, and associated factors.
Synonyms:exact_synonym: Clr6 histone deacetylase complex I/I';   Clr6L complex;   Rpd3C(L);   Sin3L complex
 alt_id: GO:0000508



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  cellular_component 20824
    cellular anatomical structure 20625
      chromatin 818
        Sin3-type complex 12
          Rpd3L complex 0
Path 2
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  cellular_component 20824
    cellular anatomical structure 20625
      organelle 13967
        intracellular organelle 13561
          intracellular membrane-bounded organelle 12003
            nucleus 7451
              nuclear lumen 4053
                nucleoplasm 3547
                  histone deacetylase complex 76
                    Sin3-type complex 12
                      Rpd3L complex 0
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