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ONTOLOGY REPORT - ANNOTATIONS

Term:osteoblast proliferation
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Accession:GO:0033687 term browser browse the term
Definition:The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.


show annotations for term's descendants           Sort by:
osteoblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin2 axin 2 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:3579503 (PMID:15790973)		 Ensembl
RGD		 PMID:15790973 GO_REF:0000107 NCBI chr10:94,393,379...94,426,579
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:1857430 (PMID:10193316)		 Ensembl
RGD		 PMID:10193316 GO_REF:0000107 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Cthrc1 collagen triple helix repeat containing 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:3830252 (PMID:18779865)		 Ensembl
RGD		 PMID:18779865 GO_REF:0000107 NCBI chr 7:72,007,372...72,017,654
Ensembl chr 7:70,122,474...70,132,756 		JBrowse link
G Fignl1 fidgetin-like 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17352653)		 UniProt
RGD		 PMID:17352653 GO_REF:0000024 NCBI chr14:90,573,090...90,595,342
Ensembl chr14:86,368,675...86,377,455 		JBrowse link
G Gata1 GATA binding protein 1 acts_upstream_of ISO MGI:2177586 (PMID:15005853) RGD PMID:15005853 NCBI chr  X:17,193,291...17,209,462
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Ift80 intraflagellar transport 80 acts_upstream_of_or_within ISO MGI:3689350|MGI:5818514 (PMID:26996322) RGD PMID:26996322 NCBI chr 2:155,455,773...155,550,082
Ensembl chr 2:153,145,795...153,240,024 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO MGI:2176174|MGI:3036209 (PMID:14769860) RGD PMID:14769860 NCBI chr19:40,081,126...40,082,910
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Lrp5 LDL receptor related protein 5 acts_upstream_of ISO MGI:2183279 (PMID:11956231) RGD PMID:11956231 NCBI chr 1:210,243,499...210,346,886
Ensembl chr 1:200,814,250...200,917,581 		JBrowse link
G Lrrc17 leucine rich repeat containing 17 NOT|involved_in ISO (PMID:19336404) RGD PMID:19336404 NCBI chr 4:14,393,632...14,424,048
Ensembl chr 4:13,501,436...13,531,845 		JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit involved_in ISO
IEA		 (PMID:26415217)
GO_REF:0000107		 RGD
Ensembl		 PMID:26415217 GO_REF:0000107 NCBI chr 1:212,219,793...212,225,214
Ensembl chr 1:202,790,466...202,795,843 		JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:1926957 (PMID:10887156)		 Ensembl
RGD		 PMID:10887156 GO_REF:0000107 NCBI chr14:83,850,894...83,934,263
Ensembl chr14:79,627,399...79,710,667 		JBrowse link
G Osr2 odd-skipped related transcription factor 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17547533)		 UniProt
RGD		 PMID:17547533 GO_REF:0000024 NCBI chr 7:66,487,841...66,495,003
Ensembl chr 7:66,487,839...66,495,224 		JBrowse link
negative regulation of osteoblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor IEP RGD PMID:23529231 RGD:7244256 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Ahr aryl hydrocarbon receptor IDA RGD PMID:12193573 RGD:625678 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Atraid all-trans retinoic acid-induced differentiation factor involved_in ISO (PMID:21723284) RGD PMID:21723284 NCBI chr 6:25,315,236...25,319,821 JBrowse link
G Axin2 axin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3579503 (PMID:15790973)		 Ensembl
RGD		 PMID:15790973 GO_REF:0000107 NCBI chr10:94,393,379...94,426,579
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857430 (PMID:10193316)		 Ensembl
RGD		 PMID:10193316 GO_REF:0000107 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 involved_in ISO
IEA
ISS		 (PMID:16216244)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:16216244 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:21,941,147...21,977,115
Ensembl chr 6:16,188,979...16,224,971 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) RGD PMID:15539560 NCBI chr 3:120,966,639...120,978,319
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Mn1 MN1 proto-oncogene, transcriptional regulator involved_in ISO (PMID:15890672) RGD PMID:15890672 NCBI chr12:45,181,794...45,220,959
Ensembl chr12:45,183,085...45,221,651 		JBrowse link
G Nell1 neural EGFL like 1 involved_in ISO
ISS		 (PMID:21723284)
GO_REF:0000024		 RGD
UniProt		 PMID:21723284 GO_REF:0000024 NCBI chr 1:108,845,462...109,709,858
Ensembl chr 1:99,709,793...100,573,860 		JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1926957 (PMID:10887156)		 Ensembl
RGD		 PMID:10887156 GO_REF:0000107 NCBI chr14:83,850,894...83,934,263
Ensembl chr14:79,627,399...79,710,667 		JBrowse link
G Plxnb1 plexin B1 involved_in ISO (PMID:22019888) RGD PMID:22019888 NCBI chr 8:118,621,961...118,647,491
Ensembl chr 8:109,744,697...109,769,027 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3045799 (PMID:14976225)
(PMID:19072540)		 Ensembl
RGD		 PMID:14976225 PMID:19072540 GO_REF:0000107 NCBI chr16:75,278,325...75,316,736
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Smad3 SMAD family member 3 involved_in ISO (PMID:21035443) RGD PMID:21035443 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Tnn tenascin N involved_in ISO (PMID:17395156) RGD PMID:17395156 NCBI chr13:74,852,586...74,919,789
Ensembl chr13:72,319,155...72,408,156 		JBrowse link
positive regulation of osteoblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:2153718 (PMID:22729085) RGD PMID:22729085 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20675382)		 Ensembl
RGD		 PMID:20675382 GO_REF:0000107 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Ccn1 cellular communication network factor 1 involved_in ISO
IEA		 (PMID:20675382)
GO_REF:0000107		 RGD
Ensembl		 PMID:20675382 GO_REF:0000107 NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Cthrc1 collagen triple helix repeat containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3830252 (PMID:18779865)		 Ensembl
RGD		 PMID:18779865 GO_REF:0000107 NCBI chr 7:72,007,372...72,017,654
Ensembl chr 7:70,122,474...70,132,756 		JBrowse link
G Fbln5 fibulin 5 involved_in ISO (PMID:26399686) RGD PMID:26399686 NCBI chr 6:126,664,100...126,742,847
Ensembl chr 6:120,899,224...120,977,755 		JBrowse link
G Gata1 GATA binding protein 1 acts_upstream_of_or_within ISO MGI:2177586 (PMID:15005853) RGD PMID:15005853 NCBI chr  X:17,193,291...17,209,462
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:26722385 RGD:11555176 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hpse heparanase involved_in IEA
ISO		 GO_REF:0000107
(PMID:20309870)
(PMID:18589009)		 Ensembl
RGD		 PMID:18589009 PMID:20309870 GO_REF:0000107 NCBI chr14:9,200,971...9,241,377
Ensembl chr14:8,896,593...8,937,010 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor IMP RGD PMID:15110779 RGD:10045881 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Itgav integrin subunit alpha V involved_in ISO (PMID:20675382) RGD PMID:20675382 NCBI chr 3:89,245,382...89,333,512
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Itgb3 integrin subunit beta 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20675382)		 Ensembl
RGD		 PMID:20675382 GO_REF:0000107 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Lrp5 LDL receptor related protein 5 acts_upstream_of_or_within ISO MGI:2183279 (PMID:11956231) RGD PMID:11956231 NCBI chr 1:210,243,499...210,346,886
Ensembl chr 1:200,814,250...200,917,581 		JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:15166119) RGD PMID:15166119 NCBI chr 8:119,878,344...119,901,189
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Sox8 SRY-box transcription factor 8 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:2154329 (PMID:15753123)		 UniProt
RGD		 PMID:15753123 GO_REF:0000024 NCBI chr10:15,089,357...15,094,345
Ensembl chr10:14,584,829...14,589,818 		JBrowse link
G Tmem119 transmembrane protein 119 involved_in ISO
IBA		 (PMID:20025746)
GO_REF:0000033		 RGD
GO_Central		 PMID:20025746 GO_REF:0000033 NCBI chr12:48,489,157...48,496,214
Ensembl chr12:42,828,418...42,835,689 		JBrowse link
regulation of osteoblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:3044427 (PMID:12756187) RGD PMID:12756187 NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Npr3 natriuretic peptide receptor 3 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:10377427)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:10377427 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:62,592,557...62,660,497
Ensembl chr 2:60,870,594...60,932,955 		JBrowse link
G Rhoa ras homolog family member A involved_in ISO (PMID:22019888) RGD PMID:22019888 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    cellular process 19543
      cell population proliferation 2273
        osteoblast proliferation 38
          negative regulation of osteoblast proliferation 14
          positive regulation of osteoblast proliferation 15
          regulation of osteoblast proliferation + 32
paths to the root