Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:mammary gland epithelial cell proliferation
go back to main search page
Accession:GO:0033598 term browser browse the term
Definition:The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.


show annotations for term's descendants           Sort by:
mammary gland epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:20075866) Ensembl
MGI		 PMID:20075866 GO_REF:0000107 NCBI chr 5:23,015,777...23,035,943
Ensembl chr 5:23,017,176...23,033,517 		JBrowse link
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15340078) Ensembl
MGI		 PMID:15340078 GO_REF:0000107 NCBI chr14:112,398,764...112,588,041
Ensembl chr14:112,398,868...112,588,037 		JBrowse link
G CCND1 cyclin D1 involved_in
acts_upstream_of
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20075866)
(PMID:11747812)		 Ensembl
MGI		 PMID:11747812 PMID:20075866 GO_REF:0000107 NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A acts_upstream_of ISO (PMID:15105443) MGI PMID:15105443 NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,792,469...200,798,854 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10683373) Ensembl
MGI		 PMID:10683373 GO_REF:0000107 NCBI chr17:51,722,633...51,723,673
Ensembl chr17:51,722,426...51,724,305 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex acts_upstream_of_or_within ISO (PMID:11747812) MGI PMID:11747812 NCBI chr14:111,316,178...111,351,669
Ensembl chr14:111,315,141...111,351,868 		JBrowse link
G EPHA2 EPH receptor A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:75,251,465...75,279,364
Ensembl chr 6:75,251,467...75,279,314 		JBrowse link
G ID2 inhibitor of DNA binding 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:127,500,759...127,503,207
Ensembl chr 3:127,500,763...127,503,257 		JBrowse link
G IQGAP3 IQ motif containing GTPase activating protein 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18604197) Ensembl
MGI		 PMID:18604197 GO_REF:0000107 NCBI chr 4:93,495,999...93,556,915
Ensembl chr 4:93,513,187...93,559,001 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 acts_upstream_of_or_within ISO (PMID:18604197) MGI PMID:18604197 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MED1 mediator complex subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20351249)
(PMID:15843544)		 Ensembl
MGI		 PMID:15843544 PMID:20351249 GO_REF:0000107 NCBI chr12:22,830,405...22,872,420
Ensembl chr12:22,841,205...22,872,409 		JBrowse link
G PHB2 prohibitin 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17065319) Ensembl
MGI		 PMID:17065319 GO_REF:0000107 NCBI chr 5:63,751,566...63,756,480
Ensembl chr 5:63,751,558...63,756,478 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22588720) Ensembl
MGI		 PMID:22588720 GO_REF:0000107 NCBI chr 5:22,406,356...22,422,412
Ensembl chr 5:22,406,368...22,421,989 		JBrowse link
G TNFSF11 TNF superfamily member 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11051546) Ensembl
MGI		 PMID:11051546 GO_REF:0000107 NCBI chr11:24,468,011...24,505,421
Ensembl chr11:24,468,110...24,505,477 		JBrowse link
epithelial cell proliferation involved in mammary gland duct elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AREG amphiregulin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17369357) Ensembl
MGI		 PMID:17369357 GO_REF:0000107 NCBI chr 8:70,417,935...70,428,106
Ensembl chr 8:70,417,923...70,428,102 		JBrowse link
G ESR1 estrogen receptor 1 acts_upstream_of_or_within ISO (PMID:12021201) MGI PMID:12021201 NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363 		JBrowse link
G MED1 mediator complex subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15647257) Ensembl
MGI		 PMID:15647257 GO_REF:0000107 NCBI chr12:22,830,405...22,872,420
Ensembl chr12:22,841,205...22,872,409 		JBrowse link
G TFAP2C transcription factor AP-2 gamma acts_upstream_of_or_within ISO (PMID:20131354) MGI PMID:20131354 NCBI chr17:57,164,400...57,174,923
Ensembl chr17:57,164,404...57,174,107 		JBrowse link
G WNT5A Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17898001) Ensembl
MGI		 PMID:17898001 GO_REF:0000107 NCBI chr13:37,344,684...37,367,215
Ensembl chr13:37,344,699...37,367,207 		JBrowse link
negative regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA2 BRCA2 DNA repair associated involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:8,805,950...8,858,128
Ensembl chr11:8,805,953...8,858,418 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A acts_upstream_of_or_within ISO (PMID:15105443) MGI PMID:15105443 NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,792,469...200,798,854 		JBrowse link
G ETV4 ETS variant transcription factor 4 acts_upstream_of_or_within ISO (PMID:18977342) MGI PMID:18977342 NCBI chr12:19,531,507...19,548,303
Ensembl chr12:19,531,603...19,548,301 		JBrowse link
G GATA3 GATA binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:63,367,684...63,397,977
Ensembl chr10:63,367,663...63,388,859 		JBrowse link
G PHB2 prohibitin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17065319) Ensembl
MGI		 PMID:17065319 GO_REF:0000107 NCBI chr 5:63,751,566...63,756,480
Ensembl chr 5:63,751,558...63,756,478 		JBrowse link
G ROBO1 roundabout guidance receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:175,348,223...176,479,482
Ensembl chr13:175,348,410...176,479,481 		JBrowse link
positive regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20075866) Ensembl
MGI		 PMID:20075866 GO_REF:0000107 NCBI chr 5:23,015,777...23,035,943
Ensembl chr 5:23,017,176...23,033,517 		JBrowse link
G CCND1 cyclin D1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20075866) Ensembl
MGI		 PMID:20075866 GO_REF:0000107 NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296 		JBrowse link
G IQGAP3 IQ motif containing GTPase activating protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18604197) Ensembl
MGI		 PMID:18604197 GO_REF:0000107 NCBI chr 4:93,495,999...93,556,915
Ensembl chr 4:93,513,187...93,559,001 		JBrowse link
G KDM5B lysine demethylase 5B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24802759) Ensembl
MGI		 PMID:24802759 GO_REF:0000107 NCBI chr10:24,739,115...24,831,537
Ensembl chr10:24,736,838...24,831,447 		JBrowse link
G MST1 macrophage stimulating 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25049204) Ensembl
MGI		 PMID:25049204 GO_REF:0000107 NCBI chr13:32,214,934...32,220,045
Ensembl chr13:32,214,937...32,219,902 		JBrowse link
G RREB1 ras responsive element binding protein 1 involved_in ISO (PMID:18394891) UniProt PMID:18394891 NCBI chr 7:4,512,286...4,639,961 JBrowse link
G RTN4 reticulon 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:86,180,022...86,252,126
Ensembl chr 3:86,180,022...86,252,126 		JBrowse link
G ZNF703 zinc finger protein 703 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:48,692,316...48,696,639
Ensembl chr15:48,692,320...48,696,644 		JBrowse link
regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10363969) Ensembl
MGI		 PMID:10363969 GO_REF:0000107 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140 		JBrowse link
G DEAF1 DEAF1 transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:404,514...427,584
Ensembl chr 2:404,533...427,542 		JBrowse link
G GPX1 glutathione peroxidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433 		JBrowse link
G HOXA5 homeobox A5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16607641) Ensembl
MGI		 PMID:16607641 GO_REF:0000107 NCBI chr18:45,429,691...45,432,723
Ensembl chr18:45,421,663...45,432,885 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17799
    cellular process 16838
      cell population proliferation 2219
        epithelial cell proliferation 552
          mammary gland epithelial cell proliferation 31
            epithelial cell proliferation involved in mammary gland bud elongation + 0
            epithelial cell proliferation involved in mammary gland duct elongation 5
            negative regulation of mammary gland epithelial cell proliferation 6
            positive regulation of mammary gland epithelial cell proliferation 8
            regulation of mammary gland epithelial cell proliferation + 18
Path 2
Term Annotations click to browse term
  biological_process 17799
    developmental process 6719
      anatomical structure development 6314
        animal organ development 3525
          gland development 633
            mammary gland development 177
              mammary gland epithelium development 81
                mammary gland epithelial cell proliferation 31
                  epithelial cell proliferation involved in mammary gland bud elongation + 0
                  epithelial cell proliferation involved in mammary gland duct elongation 5
                  negative regulation of mammary gland epithelial cell proliferation 6
                  positive regulation of mammary gland epithelial cell proliferation 8
                  regulation of mammary gland epithelial cell proliferation + 18
paths to the root