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ONTOLOGY REPORT - ANNOTATIONS


Term:elongator holoenzyme complex
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Accession:GO:0033588 term browser browse the term
Definition:A heterohexameric protein complex that is involved in modification of wobble nucleosides in tRNA. The complex can associate physically with hyperphosphorylated RNA polymerase II; it contains two discrete heterotrimeric subcomplexes.
Comment:Despite its name, this complex is no longer thought to be directly involved in transcriptional elongation (PMID:23165209).
Synonyms:related_synonym: Elongator core complex
 alt_id: GO:0033589


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elongator holoenzyme complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07053185.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 3:95,838,262...95,954,983 JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 part_of IBA
IEA
ISS
ISO
PMID:21873635
GO_REF:0000107
GO_REF:0000024
(PMID:22854966)
Ensembl
UniProt
RGD
PMID:22854966, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 5:73,503,406...73,552,798
Ensembl chr 5:73,503,407...73,552,798
JBrowse link
G Elp2 elongator acetyltransferase complex subunit 2 part_of ISS
ISO
IBA
GO_REF:0000024
(PMID:22854966)
PMID:21873635
UniProt
RGD
PMID:22854966, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr18:16,544,515...16,581,086
Ensembl chr18:16,544,508...16,581,116
JBrowse link
G Elp3 elongator acetyltransferase complex subunit 3 part_of ISO
IBA
(PMID:22854966)
PMID:21873635
RGD PMID:22854966, PMID:21873635 RGD:13792537 NCBI chr15:48,942,866...49,005,074
Ensembl chr15:48,942,871...49,005,058
JBrowse link
G Elp4 elongator acetyltransferase complex subunit 4 part_of ISO (PMID:22854966) RGD PMID:22854966 NCBI chr 3:95,733,810...95,954,987 JBrowse link
G Elp5 elongator acetyltransferase complex subunit 5 part_of ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:22854966)
UniProt
Ensembl
RGD
PMID:22854966, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr10:56,578,980...56,590,706
Ensembl chr10:56,578,985...56,591,364
JBrowse link
G Elp6 elongator acetyltransferase complex subunit 6 part_of ISS
ISO
IBA
GO_REF:0000024
(PMID:22854966)
PMID:21873635
UniProt
RGD
PMID:22854966, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:118,525,770...118,541,074
Ensembl chr 8:118,525,682...118,541,073
JBrowse link
G LOC365839 similar to elongation protein 4 homolog part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:186,630,203...186,631,703
Ensembl chr 2:186,630,278...186,631,633
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  cellular_component 20011
    protein-containing complex 6011
      intracellular protein-containing complex 769
        elongator holoenzyme complex 8
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