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ONTOLOGY REPORT - ANNOTATIONS


Term:Leydig cell differentiation
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Accession:GO:0033327 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.



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Leydig cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3717246 (MGI:4430676|PMID:19574395)
Ensembl
RGD
PMID:19574395 GO_REF:0000107 MGI:4430676 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Ccnd1 cyclin D1 IMP RGD PMID:17303663 RGD:2289137 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP RGD PMID:18502897 RGD:4781870 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 IEP RGD PMID:18502897 RGD:4781870 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Dhh desert hedgehog signaling molecule acts_upstream_of_or_within ISO MGI:1095403|MGI:1934259 (MGI:2450504|PMID:12050120), (MGI:3769860|PMID:17495005) RGD PMID:12050120 PMID:17495005 MGI:2450504 MGI:3769860 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 IEP RGD PMID:12810569 RGD:2302236 NCBI chr  X:21,089,152...21,091,597
Ensembl chr  X:21,089,122...21,109,488
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 IEP RGD PMID:18502897 RGD:4781870 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP RGD PMID:18502897 RGD:4781870 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 IEP RGD PMID:18502897 RGD:4781870 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852
JBrowse link
G Map7 microtubule-associated protein 7 acts_upstream_of_or_within ISO MGI:2148221 (MGI:1859100|PMID:10837026) RGD PMID:10837026 MGI:1859100 NCBI chr 1:14,910,433...15,037,574
Ensembl chr 1:14,910,551...15,037,574
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 IEP RGD PMID:15149725 RGD:2302287 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857494 (MGI:2445907|PMID:12399445)
Ensembl
RGD
PMID:12399445 GO_REF:0000107 MGI:2445907 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2159321 (MGI:2150593|PMID:11564714)
Ensembl
RGD
PMID:11564714 GO_REF:0000107 MGI:2150593 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2449440|MGI:3689423 (MGI:3820330|PMID:19056881)
Ensembl
RGD
PMID:19056881 GO_REF:0000107 MGI:3820330 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Plekha1 pleckstrin homology domain containing A1 acts_upstream_of_or_within ISO MGI:3526857 (MGI:3820330|PMID:19056881) RGD PMID:19056881 MGI:3820330 NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156
JBrowse link
G Sf1 splicing factor 1 acts_upstream_of_or_within ISO MGI:94891 (MGI:3769860|PMID:17495005) RGD PMID:17495005 MGI:3769860 NCBI chr 1:203,670,016...203,683,432
Ensembl chr 1:203,670,018...203,684,330
JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 acts_upstream_of_or_within ISO MGI:3526851 (MGI:3820330|PMID:19056881) RGD PMID:19056881 MGI:3820330 NCBI chr20:29,047,793...29,094,209
Ensembl chr20:29,047,796...29,094,084
JBrowse link
G Tmf1 TATA element modulatory factor 1 acts_upstream_of_or_within ISO MGI:4867392 (MGI:5469555|PMID:23000399) RGD PMID:23000399 MGI:5469555 NCBI chr 4:129,759,952...129,785,705
Ensembl chr 4:129,763,114...129,785,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19391
    developmental process 6775
      developmental process involved in reproduction 1199
        Leydig cell differentiation 18
Path 2
Term Annotations click to browse term
  biological_process 19391
    developmental process 6775
      anatomical structure development 6201
        multicellular organism development 5638
          system development 5307
            reproductive system development 590
              reproductive structure development 585
                gonad development 327
                  male gonad development 202
                    Leydig cell differentiation 18
paths to the root