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ONTOLOGY REPORT - ANNOTATIONS


Term:response to vitamin D
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Accession:GO:0033280 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.
Synonyms:exact_synonym: response to calciferol
 narrow_synonym: response to cholecalciferol;   response to ergocalciferol


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response to vitamin D term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A IEP RGD PMID:20013813 RGD:2315563 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated ISO (PMID:17023519) RGD PMID:17023519 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Bglap bone gamma-carboxyglutamate protein ISO (PMID:17023519) RGD PMID:17023519 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bmp7 bone morphogenetic protein 7 IEP RGD PMID:17554252 RGD:2289035 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Cd4 Cd4 molecule IEP RGD PMID:8759780 RGD:10058969 NCBI chr 4:157,381,862...157,408,357
Ensembl chr 4:157,383,052...157,408,176
JBrowse link
G Crym crystallin, mu IEP RGD PMID:2809492 RGD:2303730 NCBI chr 1:189,944,895...189,960,069
Ensembl chr 1:189,944,895...189,960,073
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 IEP RGD PMID:15637289 RGD:2311387 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 ISO
IBA
(PMID:16720713)
PMID:21873635
RGD PMID:16720713, PMID:21873635 RGD:13792537 NCBI chr 3:168,097,484...168,111,920
Ensembl chr 3:168,097,485...168,111,920
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 IDA
IBA
ISO
PMID:21873635
(MGI:MGI:1097206|PMID:9295274)
(PMID:16549446)
RGD PMID:9295274, PMID:16549446, PMID:3000565, PMID:21873635 MGI:MGI:1097206, RGD:2307325, RGD:13792537 NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005
JBrowse link
G Ggcx gamma-glutamyl carboxylase IEP RGD PMID:3840747 RGD:11040515 NCBI chr 4:100,277,345...100,293,097
Ensembl chr 4:100,277,391...100,293,250
JBrowse link
G Il1b interleukin 1 beta IEP RGD PMID:17621647 RGD:1626651 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Insr insulin receptor IEP 1,25-dihydroxyvitamin D3, in diabetic rats RGD PMID:18638371 RGD:2307025 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Kl Klotho IEP RGD PMID:20631679 RGD:10403078 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
G LOC100909462 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Lrp2 LDL receptor related protein 2 IEP RGD PMID:9541123 RGD:1641848 NCBI chr 3:55,665,153...55,822,484
Ensembl chr 3:55,665,145...55,822,551
JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked IEP RGD PMID:14693675 RGD:11556273 NCBI chr  X:40,460,047...40,717,982
Ensembl chr  X:40,460,047...40,717,982
JBrowse link
G Pla2g4a phospholipase A2 group IVA IEP RGD PMID:15225789 RGD:1642467 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Prkcb protein kinase C, beta IEP RGD PMID:10206343 RGD:1625620 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IEP RGD PMID:18348265 RGD:2300284 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pth parathyroid hormone IEP RGD PMID:22926202 RGD:7242796 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link
G Rxra retinoid X receptor alpha IEP RGD PMID:12048211 RGD:625496 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Slc8a2 solute carrier family 8 member A2 IEP RGD PMID:20113508 RGD:2316972 NCBI chr 1:78,029,555...78,054,042
Ensembl chr 1:78,025,995...78,060,111
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO (PMID:16720713) RGD PMID:16720713 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Stc1 stanniocalcin 1 IEP RGD PMID:11702003 RGD:2324701 NCBI chr15:50,891,137...50,901,791
Ensembl chr15:50,891,127...50,903,162
JBrowse link
G Stc2 stanniocalcin 2 IEP RGD PMID:10508929 RGD:634221 NCBI chr10:16,542,909...16,552,675
Ensembl chr10:16,542,882...16,553,295
JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEP RGD PMID:11956143, PMID:24613393 RGD:2302111, RGD:11073674 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb2 transforming growth factor, beta 2 IEP RGD PMID:11956143 RGD:2302111 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tpcn2 two pore segment channel 2 IEP RGD PMID:20197420 RGD:9585651 NCBI chr 1:218,419,182...218,448,902
Ensembl chr 1:218,419,184...218,448,877
JBrowse link
G Trim25 tripartite motif-containing 25 IEP RGD PMID:10425199 RGD:1300518 NCBI chr10:76,343,847...76,362,159
Ensembl chr10:76,343,847...76,362,145
JBrowse link
G Tyr tyrosinase IEP RGD PMID:6175546 RGD:8694330 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
JBrowse link
G Vim vimentin IEP RGD PMID:18687349 RGD:6480443 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
cellular response to vitamin D term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 IEP RGD PMID:11108265 RGD:9681746 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 IEP RGD PMID:11277270 RGD:2317730 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579
JBrowse link
G Bglap bone gamma-carboxyglutamate protein IEP RGD PMID:6607920, PMID:3257212 RGD:2316174, RGD:6483560 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Casr calcium-sensing receptor IEP 1,25-dihydroxycholecalciferol (calcitriol) RGD PMID:21940515 RGD:7205697 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771
JBrowse link
G Fes FES proto-oncogene, tyrosine kinase ISO (PMID:28389358) RGD PMID:28389358 NCBI chr 1:142,174,648...142,183,884
Ensembl chr 1:142,174,648...142,183,884
JBrowse link
G Fgf23 fibroblast growth factor 23 IEP RGD PMID:23263654 RGD:10044209 NCBI chr 4:159,622,404...159,630,082
Ensembl chr 4:159,622,404...159,630,082
JBrowse link
G Fzd1 frizzled class receptor 1 IEP RGD PMID:1334084 RGD:61590 NCBI chr 4:26,470,864...26,475,262
Ensembl chr 4:26,470,864...26,475,262
JBrowse link
G Fzd2 frizzled class receptor 2 IEP RGD PMID:1334084 RGD:61590 NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
JBrowse link
G Gdap1 ganglioside-induced differentiation-associated-protein 1 IEP RGD PMID:25449168 RGD:12738378 NCBI chr 5:1,328,963...1,347,946
Ensembl chr 5:1,328,913...1,347,921
JBrowse link
G Il15 interleukin 15 IEP RGD PMID:15637289 RGD:2311387 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
JBrowse link
G Itgb1 integrin subunit beta 1 IEP calcitriol RGD PMID:20304064 RGD:2325261 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 IEP RGD PMID:10025676 RGD:10412059 NCBI chr 6:21,203,502...21,600,441
Ensembl chr 6:21,203,502...21,600,451
JBrowse link
G Mmp1 matrix metallopeptidase 1 IEP RGD PMID:22064970 RGD:7207281 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Nos2 nitric oxide synthase 2 IEP RGD PMID:18534083 RGD:4891908 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 IDA RGD PMID:15862831 RGD:9999173 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Penk proenkephalin IEP RGD PMID:8584038 RGD:10003035 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked IEP RGD PMID:15337762 RGD:11556251 NCBI chr  X:40,460,047...40,717,982
Ensembl chr  X:40,460,047...40,717,982
JBrowse link
G Ptn pleiotrophin IEP RGD PMID:21153232 RGD:9831436 NCBI chr 4:64,239,156...64,330,996
Ensembl chr 4:64,239,158...64,330,996
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 IEA
ISO
GO_REF:0000107
(PMID:16149051)
Ensembl
RGD
PMID:16149051 GO_REF:0000107 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 IDA RGD PMID:14978251 RGD:2317006 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Tnc tenascin C IEP RGD PMID:10502285 RGD:4889620 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671
JBrowse link
G Vdr vitamin D receptor IEP RGD PMID:9753201 RGD:8158092 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
negative regulation of vitamin D receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kank2 KN motif and ankyrin repeat domains 2 ISO
IBA
(PMID:24671081)
PMID:21873635
RGD PMID:24671081, PMID:21873635 RGD:13792537 NCBI chr 8:22,792,000...22,821,459
Ensembl chr 8:22,791,995...22,821,397
JBrowse link
G Snai2 snail family transcriptional repressor 2 ISO (PMID:19502595) RGD PMID:19502595 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
positive regulation of vitamin D receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 ISO (PMID:16549446) RGD PMID:16549446 NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005
JBrowse link
G Mn1 MN1 proto-oncogene, transcriptional regulator ISO (PMID:15890672) RGD PMID:15890672 NCBI chr12:51,214,192...51,250,230
Ensembl chr12:51,214,192...51,250,230
JBrowse link
G Snw1 SNW domain containing 1 ISO (PMID:11514567), (PMID:9632709) RGD PMID:9632709, PMID:11514567 NCBI chr 6:111,483,698...111,507,782
Ensembl chr 6:111,483,703...111,507,782
JBrowse link
regulation of vitamin D receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Med1 mediator complex subunit 1 ISO MGI:MGI:1861125 (MGI:MGI:3655015|PMID:16324150) RGD PMID:16324150 MGI:MGI:3655015 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Snw1 SNW domain containing 1 ISO (PMID:14985122) RGD PMID:14985122 NCBI chr 6:111,483,698...111,507,782
Ensembl chr 6:111,483,703...111,507,782
JBrowse link
G Trim24 tripartite motif-containing 24 ISO MGI:MGI:3772051 (MGI:MGI:3776949|PMID:18287084) RGD PMID:18287084 MGI:MGI:3776949 NCBI chr 4:65,632,278...65,684,746
Ensembl chr 4:65,637,407...65,684,743
JBrowse link
vitamin D receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase ISO (PMID:22720752) RGD PMID:22720752 NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555
JBrowse link
G Vdr vitamin D receptor IEA
ISO
GO_REF:0000107
(PMID:16549446), (PMID:28698609)
Ensembl
RGD
PMID:16549446, PMID:28698609 GO_REF:0000107 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    response to stimulus 10583
      response to chemical 6342
        response to oxygen-containing compound 2344
          response to vitamin D 58
            cellular response to vitamin D + 30
Path 2
Term Annotations click to browse term
  biological_process 20028
    response to stimulus 10583
      response to external stimulus 3204
        response to extracellular stimulus 763
          response to nutrient levels 732
            response to nutrient 311
              response to vitamin 179
                response to vitamin D 58
                  cellular response to vitamin D + 30
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.