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ONTOLOGY REPORT - ANNOTATIONS


Term:nuclear DNA replication
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Accession:GO:0033260 term browser browse the term
Definition:The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.
Synonyms:exact_synonym: DNA replication involved in S phase;   nuclear cell cycle DNA replication
 related_synonym: DNA replication during S phase



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nuclear DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 involved_in ISO MGI:4127920 (MGI:5763555|PMID:25404367) RGD PMID:25404367 MGI:5763555 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845
JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:30,911,616...30,933,150
Ensembl chr11:30,923,239...30,932,889
JBrowse link
G Zfp830 zinc finger protein 830 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:4950703 (MGI:4950701|PMID:21191184)
RGD PMID:21191184 PMID:21873635 MGI:4950701, RGD:13792537 NCBI chr10:67,701,340...67,702,804
Ensembl chr10:67,701,073...67,704,523
JBrowse link
DNA replication preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in IBA
ISO
PMID:21873635
(PMID:11125146)
RGD PMID:11125146 PMID:21873635 RGD:13792537 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Gmnn geminin, DNA replication inhibitor involved_in ISO (PMID:11125146) RGD PMID:11125146 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054
JBrowse link
DNA strand elongation involved in mitotic DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gins1 GINS complex subunit 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936
JBrowse link
mitotic DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mcm6 minichromosome maintenance complex component 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
JBrowse link
mitotic DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gins3 GINS complex subunit 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:9,420,085...9,428,621
Ensembl chr19:9,420,086...9,428,687
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536
JBrowse link
mitotic DNA replication preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc45 cell division cycle 45 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
JBrowse link
mitotic DNA replication termination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtfdc1 replication termination factor 2 domain containing 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:161,208,005...161,237,687
Ensembl chr 3:161,208,049...161,237,687
JBrowse link
mitotic recombination-dependent replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated involved_in IEA
ISO
GO_REF:0000107
(PMID:21076401)
Ensembl
RGD
PMID:21076401 GO_REF:0000107 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Rad51 RAD51 recombinase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
JBrowse link
mitotic telomere maintenance via semi-conservative replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dna2 DNA replication helicase/nuclease 2 involved_in ISO (MGI:5499273|PMID:23604072) RGD PMID:23604072 MGI:5499273 NCBI chr20:25,661,652...25,690,598 JBrowse link
G Pcna proliferating cell nuclear antigen involved_in ISO UniProtKB:Q0VGM9 (MGI:5522574|PMID:24115439) RGD PMID:24115439 MGI:5522574 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5522574|PMID:24115439) RGD PMID:24115439 MGI:5522574 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348
JBrowse link
Okazaki fragment processing involved in mitotic DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lig1 DNA ligase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413
JBrowse link
positive regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (MGI:79015|PMID:2161540) RGD PMID:2161540 MGI:79015 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
positive regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5568153|PMID:24651726)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:24651726 GO_REF:0000024 GO_REF:0000107 MGI:5568153 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330
JBrowse link
G Cdc7 cell division cycle 7 involved_in ISO (PMID:15668232) RGD PMID:15668232 NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778
JBrowse link
G Dbf4 DBF4 zinc finger involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066
JBrowse link
G Dbf4b DBF4 zinc finger B involved_in ISO (PMID:15668232) RGD PMID:15668232 NCBI chr10:87,713,805...87,719,197 JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO (PMID:20237820) RGD PMID:20237820 NCBI chr 3:106,368,455...106,465,716
Ensembl chr 3:106,368,455...106,467,911
JBrowse link
G Wiz WIZ zinc finger involved_in ISO (PMID:23545495) RGD PMID:23545495 NCBI chr 7:11,366,837...11,395,279
Ensembl chr 7:11,367,035...11,395,490
JBrowse link
pre-replicative complex assembly involved in nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mcm2 minichromosome maintenance complex component 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
JBrowse link
G Orc3 origin recognition complex, subunit 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:49,123,758...49,181,552
Ensembl chr 5:49,126,955...49,181,633
JBrowse link
regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033 (MGI:3583382|PMID:15980864) RGD PMID:15980864 MGI:3583382 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110
JBrowse link
regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase involved_in ISO (PMID:19734146) RGD PMID:19734146 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 acts_upstream_of_or_within ISO (MGI:2159541|PMID:11850834) RGD PMID:11850834 MGI:2159541 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Dach1 dachshund family transcription factor 1 involved_in ISO (MGI:5619482|PMID:16980615) RGD PMID:16980615 MGI:5619482 NCBI chr15:74,528,122...74,909,811
Ensembl chr15:74,529,208...74,909,922
JBrowse link
G Ilkap ILK associated serine/threonine phosphatase IDA RGD PMID:9857069 RGD:632254 NCBI chr 9:91,966,440...91,988,791
Ensembl chr 9:91,966,441...91,988,892
JBrowse link
G Nuggc nuclear GTPase, germinal center associated involved_in ISO (PMID:19734146) RGD PMID:19734146 NCBI chr15:39,821,851...39,866,122
Ensembl chr15:39,821,855...39,866,122
JBrowse link
telomere maintenance via semi-conservative replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Upf1 UPF1, RNA helicase and ATPase involved_in ISO (PMID:21829167) RGD PMID:21829167 NCBI chr16:19,076,594...19,097,365
Ensembl chr16:19,076,322...19,096,568
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    cellular process 18252
      cell cycle process 1175
        cell cycle DNA replication 41
          nuclear DNA replication 36
            DNA replication preinitiation complex assembly + 3
            DNA strand elongation involved in nuclear cell cycle DNA replication + 1
            mitotic DNA replication + 14
            negative regulation of nuclear cell cycle DNA replication + 0
            nuclear DNA replication DNA duplex unwinding + 0
            nuclear DNA replication DNA ligation + 0
            nuclear DNA replication termination + 1
            nuclear cell cycle DNA replication initiation + 5
            positive regulation of nuclear cell cycle DNA replication + 7
            pre-replicative complex assembly involved in nuclear cell cycle DNA replication + 7
            premeiotic DNA replication + 0
            regulation of nuclear cell cycle DNA replication + 13
            synthesis of RNA primer involved in nuclear cell cycle DNA replication + 0
            telomere maintenance via semi-conservative replication + 4
Path 2
Term Annotations click to browse term
  biological_process 19390
    metabolic process 11736
      organic substance metabolic process 11278
        macromolecule metabolic process 9736
          cellular macromolecule metabolic process 8148
            cellular macromolecule biosynthetic process 4937
              DNA replication 253
                DNA-dependent DNA replication 150
                  cell cycle DNA replication 41
                    nuclear DNA replication 36
                      DNA replication preinitiation complex assembly + 3
                      DNA strand elongation involved in nuclear cell cycle DNA replication + 1
                      mitotic DNA replication + 14
                      negative regulation of nuclear cell cycle DNA replication + 0
                      nuclear DNA replication DNA duplex unwinding + 0
                      nuclear DNA replication DNA ligation + 0
                      nuclear DNA replication termination + 1
                      nuclear cell cycle DNA replication initiation + 5
                      positive regulation of nuclear cell cycle DNA replication + 7
                      pre-replicative complex assembly involved in nuclear cell cycle DNA replication + 7
                      premeiotic DNA replication + 0
                      regulation of nuclear cell cycle DNA replication + 13
                      synthesis of RNA primer involved in nuclear cell cycle DNA replication + 0
                      telomere maintenance via semi-conservative replication + 4
paths to the root