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ONTOLOGY REPORT - ANNOTATIONS

Term:nuclear DNA replication
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Accession:GO:0033260 term browser browse the term
Definition:The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.
Synonyms:exact_synonym: DNA replication involved in S phase;   nuclear cell cycle DNA replication
 related_synonym: DNA replication during S phase
 only_in_taxon: NCBITaxon:2759 ! Eukaryota


show annotations for term's descendants           Sort by:
nuclear DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 involved_in ISO MGI:4127920 (PMID:25404367) RGD PMID:25404367 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:30,919,834...30,933,150
Ensembl chr11:30,923,239...30,932,889 		JBrowse link
G Zfp830 zinc finger protein 830 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:4950703 (PMID:21191184)		 GO_Central
RGD		 PMID:21191184 GO_REF:0000033 NCBI chr10:67,701,340...67,702,804
Ensembl chr10:67,701,073...67,704,523 		JBrowse link
DNA replication preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO
IBA		 (PMID:11125146)
GO_REF:0000033		 RGD
GO_Central		 PMID:11125146 GO_REF:0000033 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659 		JBrowse link
G Gmnn geminin, DNA replication inhibitor involved_in ISO (PMID:11125146) RGD PMID:11125146 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054 		JBrowse link
DNA strand elongation involved in mitotic DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gins1 GINS complex subunit 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936 		JBrowse link
DNA synthesis involved in mitotic DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tk1 thymidine kinase 1 involved_in ISO (PMID:14697231) RGD PMID:14697231 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920 		JBrowse link
mitotic DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gins3 GINS complex subunit 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:9,420,085...9,428,621
Ensembl chr19:9,420,086...9,428,687 		JBrowse link
G Mcm2 minichromosome maintenance complex component 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847 		JBrowse link
G Mcm3 minichromosome maintenance complex component 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314 		JBrowse link
G Mcm4 minichromosome maintenance complex component 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144 		JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536 		JBrowse link
mitotic DNA replication preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc45 cell division cycle 45 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619 		JBrowse link
mitotic DNA replication termination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtfdc1 replication termination factor 2 domain containing 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:161,208,005...161,237,687
Ensembl chr 3:161,208,049...161,237,687 		JBrowse link
mitotic DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Recql5 RecQ like helicase 5 involved_in ISO (PMID:28575661) RGD PMID:28575661 NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652 		JBrowse link
mitotic recombination-dependent replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated involved_in IEA
ISO		 GO_REF:0000107
(PMID:21076401)		 Ensembl
RGD		 PMID:21076401 GO_REF:0000107 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567 		JBrowse link
G Rad51 RAD51 recombinase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
mitotic telomere maintenance via semi-conservative replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcna proliferating cell nuclear antigen involved_in ISO UniProtKB:Q0VGM9 (MGI:5522574|PMID:24115439) RGD PMID:24115439 MGI:5522574 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5522574|PMID:24115439) RGD PMID:24115439 MGI:5522574 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
Okazaki fragment processing involved in mitotic DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lig1 DNA ligase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413 		JBrowse link
positive regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (PMID:2161540) RGD PMID:2161540 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
positive regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5568153|PMID:24651726)		 UniProt
Ensembl
RGD		 PMID:24651726 GO_REF:0000024 GO_REF:0000107 MGI:5568153 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Cdc7 cell division cycle 7 involved_in ISO (PMID:15668232) RGD PMID:15668232 NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778 		JBrowse link
G Dbf4 DBF4-CDC7 kinase regulatory subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066 		JBrowse link
G Dbf4b DBF4B-CDC7 kinase regulatory subunit involved_in ISO (PMID:15668232) RGD PMID:15668232 NCBI chr10:87,713,805...87,719,197 JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO (PMID:20237820) RGD PMID:20237820 NCBI chr 3:106,368,455...106,465,716
Ensembl chr 3:106,368,455...106,467,911 		JBrowse link
G Wiz WIZ zinc finger involved_in ISO (PMID:23545495) RGD PMID:23545495 NCBI chr 7:11,366,837...11,395,279
Ensembl chr 7:11,367,035...11,395,490 		JBrowse link
regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033 (PMID:15980864) RGD PMID:15980864 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110 		JBrowse link
regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase involved_in ISO (PMID:19734146) RGD PMID:19734146 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972 		JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 acts_upstream_of_or_within ISO (PMID:11850834) RGD PMID:11850834 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659 		JBrowse link
G Dach1 dachshund family transcription factor 1 involved_in ISO (MGI:5619482|PMID:16980615) RGD PMID:16980615 MGI:5619482 NCBI chr15:74,528,122...74,909,811
Ensembl chr15:74,529,208...74,909,922 		JBrowse link
G Ilkap ILK associated serine/threonine phosphatase IDA RGD PMID:9857069 RGD:632254 NCBI chr 9:91,966,440...91,988,791
Ensembl chr 9:91,966,441...91,988,892 		JBrowse link
G Nuggc nuclear GTPase, germinal center associated involved_in ISO (PMID:19734146) RGD PMID:19734146 NCBI chr15:39,821,851...39,866,122
Ensembl chr15:39,821,855...39,866,122 		JBrowse link
telomere maintenance via semi-conservative replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Upf1 UPF1, RNA helicase and ATPase involved_in ISO (PMID:21829167) RGD PMID:21829167 NCBI chr16:19,076,594...19,097,365
Ensembl chr16:19,076,322...19,096,568 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    cellular process 18524
      cell cycle process 1298
        cell cycle DNA replication 38
          nuclear DNA replication 33
            DNA replication preinitiation complex assembly + 3
            DNA strand elongation involved in nuclear cell cycle DNA replication + 1
            mitotic DNA replication + 15
            negative regulation of nuclear cell cycle DNA replication + 0
            nuclear DNA replication DNA duplex unwinding + 0
            nuclear DNA replication DNA ligation + 0
            nuclear DNA replication termination + 1
            nuclear cell cycle DNA replication initiation + 5
            positive regulation of nuclear cell cycle DNA replication + 7
            pre-replicative complex assembly involved in nuclear cell cycle DNA replication + 0
            premeiotic DNA replication + 0
            regulation of nuclear cell cycle DNA replication + 13
            telomere maintenance via semi-conservative replication + 3
Path 2
Term Annotations click to browse term
  biological_process 20115
    metabolic process 12289
      primary metabolic process 10923
        nucleobase-containing compound metabolic process 5736
          nucleic acid metabolic process 5148
            DNA metabolic process 960
              DNA replication 272
                DNA-templated DNA replication 161
                  cell cycle DNA replication 38
                    nuclear DNA replication 33
                      DNA replication preinitiation complex assembly + 3
                      DNA strand elongation involved in nuclear cell cycle DNA replication + 1
                      mitotic DNA replication + 15
                      negative regulation of nuclear cell cycle DNA replication + 0
                      nuclear DNA replication DNA duplex unwinding + 0
                      nuclear DNA replication DNA ligation + 0
                      nuclear DNA replication termination + 1
                      nuclear cell cycle DNA replication initiation + 5
                      positive regulation of nuclear cell cycle DNA replication + 7
                      pre-replicative complex assembly involved in nuclear cell cycle DNA replication + 0
                      premeiotic DNA replication + 0
                      regulation of nuclear cell cycle DNA replication + 13
                      telomere maintenance via semi-conservative replication + 3
paths to the root