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ONTOLOGY REPORT - ANNOTATIONS

Term:iron import into cell
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Accession:GO:0033212 term browser browse the term
Definition:The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
Synonyms:narrow_synonym: ferrous ion import;   ferrous iron import;   ferrous iron uptake
 related_synonym: iron assimilation
 alt_id: GO:0070627

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iron import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc11a2 solute carrier family 11 member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11739192) Ensembl
MGI
TreeGrafter		 PMID:11739192 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936512:8,590,302...8,622,121
Ensembl chrNW_004936512:8,586,262...8,623,597 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 involved_in ISO (MGI:6392986|PMID:20682781)
(PMID:20682781)		 UniProt PMID:20682781 MGI:6392986 NCBI chrNW_004939045:1...7,491 JBrowse link
G Steap3 STEAP3 metalloreductase acts_upstream_of_or_within ISO (PMID:16609065) MGI PMID:16609065 NCBI chrNW_004936469:51,084,250...51,121,738
Ensembl chrNW_004936469:51,054,517...51,126,664 		JBrowse link
G Steap4 STEAP4 metalloreductase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16609065) Ensembl
MGI		 PMID:16609065 GO_REF:0000107 NCBI chrNW_004936763:645,910...671,674
Ensembl chrNW_004936763:645,858...670,863 		JBrowse link
endocytic iron import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tfr2 transferrin receptor 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936543:667,570...681,872
Ensembl chrNW_004936543:668,157...682,174 		JBrowse link
iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc39a8 solute carrier family 39 member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936520:961,376...1,036,801
Ensembl chrNW_004936520:962,756...1,037,274 		JBrowse link
G Steap2 STEAP2 metalloreductase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16609065) Ensembl
MGI		 PMID:16609065 GO_REF:0000107 NCBI chrNW_004936621:3,784,628...3,806,787
Ensembl chrNW_004936621:3,779,745...3,806,851 		JBrowse link
negative regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iscu iron-sulfur cluster assembly enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936769:492,024...498,587
Ensembl chrNW_004936769:491,530...498,692 		JBrowse link
positive regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (MGI:6304699|PMID:29061364) ARUK-UCL PMID:29061364 MGI:6304699 NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452 		JBrowse link
G Lcn2 lipocalin 2 ISO RGD PMID:25557118 RGD:126790477 NCBI chrNW_004936487:15,721,752...15,725,396
Ensembl chrNW_004936487:15,721,684...15,728,221 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15871
    localization 5129
      establishment of localization 4439
        establishment of localization in cell 2017
          iron import into cell 10
            endocytic iron import into cell + 1
            heme import into cell + 0
            iron ion import across plasma membrane + 5
            reductive iron assimilation 0
            siderophore-dependent iron import into cell + 0
Path 2
Term Annotations click to browse term
  biological_process 15871
    localization 5129
      establishment of localization 4439
        transport 4141
          monoatomic ion transport 1131
            monoatomic cation transport 950
              metal ion transport 825
                transition metal ion transport 105
                  iron ion transport 61
                    iron import into cell 10
                      endocytic iron import into cell + 1
                      heme import into cell + 0
                      iron ion import across plasma membrane + 5
                      reductive iron assimilation 0
                      siderophore-dependent iron import into cell + 0
paths to the root