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ONTOLOGY REPORT - ANNOTATIONS

Term:iron import into cell
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Accession:GO:0033212 term browser browse the term
Definition:The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
Synonyms:narrow_synonym: ferrous ion import;   ferrous iron import;   ferrous iron uptake
 related_synonym: iron assimilation
 alt_id: GO:0070627

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iron import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc39a14 solute carrier family 39 member 14 involved_in ISO (PMID:20682781)
(MGI:6392986|PMID:20682781)		 UniProt PMID:20682781 MGI:6392986 NCBI chrNW_004955403:45,828,247...45,867,309
Ensembl chrNW_004955403:45,827,942...45,867,309 		JBrowse link
G Steap3 STEAP3 metalloreductase acts_upstream_of_or_within ISO (PMID:16609065) MGI PMID:16609065 NCBI chrNW_004955459:10,441,906...10,485,235
Ensembl chrNW_004955459:10,441,752...10,485,269 		JBrowse link
G Steap4 STEAP4 metalloreductase acts_upstream_of_or_within ISO (PMID:16609065) MGI PMID:16609065 NCBI chrNW_004955432:5,618,086...5,641,372
Ensembl chrNW_004955432:5,618,086...5,641,565 		JBrowse link
endocytic iron import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tfr2 transferrin receptor 2 involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chrNW_004955573:272,315...289,227
Ensembl chrNW_004955573:272,289...291,668 		JBrowse link
iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc39a8 solute carrier family 39 member 8 involved_in ISO (PMID:22898811)
(MGI:7339319|PMID:22898811)
(MGI:6383325|PMID:30015240)		 UniProt PMID:22898811 PMID:30015240 MGI:6383325 MGI:7339319 RGD:15090842 NCBI chrNW_004955496:6,016,727...6,106,965
Ensembl chrNW_004955496:6,040,029...6,109,907 		JBrowse link
G Steap2 STEAP2 metalloreductase acts_upstream_of_or_within ISO (PMID:16609065) MGI PMID:16609065 NCBI chrNW_004955432:7,455,731...7,499,863
Ensembl chrNW_004955432:7,456,514...7,490,381 		JBrowse link
negative regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iscu iron-sulfur cluster assembly enzyme involved_in ISO (PMID:20436681) ARUK-UCL PMID:20436681 NCBI chrNW_004955455:9,833,924...9,840,547
Ensembl chrNW_004955455:9,833,924...9,841,619 		JBrowse link
positive regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (MGI:6304699|PMID:29061364) ARUK-UCL PMID:29061364 MGI:6304699 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    localization 4270
      establishment of localization 3607
        establishment of localization in cell 1686
          iron import into cell 8
            endocytic iron import into cell + 1
            heme import into cell + 0
            iron ion import across plasma membrane + 4
            reductive iron assimilation 0
            siderophore-dependent iron import into cell + 0
Path 2
Term Annotations click to browse term
  biological_process 12346
    localization 4270
      establishment of localization 3607
        transport 3331
          monoatomic ion transport 848
            monoatomic cation transport 735
              metal ion transport 678
                transition metal ion transport 83
                  iron ion transport 45
                    iron import into cell 8
                      endocytic iron import into cell + 1
                      heme import into cell + 0
                      iron ion import across plasma membrane + 4
                      reductive iron assimilation 0
                      siderophore-dependent iron import into cell + 0
paths to the root